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Poster Sessions

Poster Session I

Wednesday, September 16, 2015 — 3:30 p.m. – 5:00 p.m. — FAES Terrace

NLM
COMPBIO-1

Validating a 16S rRNA multi-region approach using mock samples
Author(s): JJ Barb, AJ Oler, HS Kim, N Chalmers, G Wallen, A Cashion, PJ Munson, NJ Ames

CIT
COMPBIO-2
NIA
COMPBIO-3
NHGRI
COMPBIO-4

Classification of telomeropathies from clinical data: A machine learning approach
Author(s): J Candia, H Leuva, P Scheinberg, D Townsley, NS Young

NHLBI
COMPBIO-5
CIT
COMPBIO-6

mRNA structure impacts on protein structure
Author(s): G Faure, AY Ogurtsov, SA Shabalina, EV Koonin

NLM
COMPBIO-7

Alview: Portable Software for Viewing Sequence Reads in BAM Formatted Files
Author(s): R Finney, Q Chen, C Nguyen, CH Hsu, C Yan, Y Hu, M Abawi, X Bian, D Meerzaman

NCI
COMPBIO-8

The Use of Latent Dirichlet Allocation to Measure Disease Similarity
Author(s): JM Frick, R Guha, NT Southall, DT Nguyen

NCATS
COMPBIO-9
NLM
COMPBIO-10
NCI
COMPBIO-11
FDA/CBER
COMPBIO-12

Overlaid arrow detection for labeling biomedical image regions
Author(s): S Kc, L Wendling, S Antani, GR Thoma

NLM
COMPBIO-13
NLM
COMPBIO-14

Genome data at NCBI–easier access, more formats, improved presentation
Author(s): P Kitts, M DiCuccio, A Kimchi, T Murphy, K Pruitt, T Tatusova

NLM
COMPBIO-15
NIAMS
COMPBIO-16
NCI
COMPBIO-17
NLM
COMPBIO-18
NLM
COMPBIO-19

Analyzing the oral microbiome: Does utilization of multiple 16S rRNA regions allow for additional bacterial identification?
Author(s): A Ranucci, H Kim, J Barb, A Oler, N Chalmers, A Cashion, G Wallen, N Ames

CC
COMPBIO-20
NCI
COMPBIO-21

Differentially Expressed MicroRNAs in Type 1 Diabetes and Their Targeted Pathways
Author(s): A Wali, S Dusmatova, R Varghese, H Ressom, D Kumar, SG Rane

NIDDK
COMPBIO-22
NIAID
COMPBIO-23

Nephele: A cloud-based scientific computing platform for improved efficiency, standardization, and collaboration in microbiome data analysis
Author(s): N Weber, M Coakley, J Dommer, A Gabrielian, R Kaur, L Kim, A Levitsky, D Liou, P Macmenamin, J Ning, K Noble, A Oler, M Quiñones, R Squires, D Hurt

NIAID
COMPBIO-24
CC
COMPBIO-25
NIDDK
HEALTH-1

Relationships between smoking and sleep problems in Black and White adolescents
Author(s): K Choi, A Bellatorre, D Lewin, D Haynie, B Simons-Morton

NIMHD
HEALTH-2
NIDDK
HEALTH-3
NCI
HEALTH-4

Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome and metabolic cross talk in adipose tissue
Author(s): F Ahmad, YW Chung, Y Tang, SC Hockman, S Liu, Y Khan, K Huo, MJ Amar, AT Remaley, VC Manganiello

NHLBI
MOLBIO-1
NICHD
MOLBIO-2

BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin
Author(s): DN Ballachanda, C Case-Borden, A Gegonne, CH Hsu, Q Chen, D Meerzaman, DS Singer

NCI
MOLBIO-3
NCI
MOLBIO-4
NEI
MOLBIO-5
NIDDK
MOLBIO-6
NIAMS
MOLBIO-7
NCI
MOLBIO-8
NIAAA
MOLBIO-9

Absence of IQGAP1 impairs insulin signaling and leads to insulin resistance
Author(s): AC Hedman, B Chawla, HH Erdemir, Z Li, DB Sacks

CC
MOLBIO-10

Discovery of small PEDF peptides that promote photoreceptor survival
Author(s): A Hernandez-Pinto, P Subramanian, SP Becerra

NEI
MOLBIO-11

Disruption of endometrial NELF transcriptional pausing complex impairs early pregnancy
Author(s): SC Hewitt, W Winuthayanon, KJ Hamilton, L Donoghue, JF Foley, GW Muse, JP Lydon, FJ DeMayo, K Adelman, KS Korach

NIEHS
MOLBIO-12

A new potential therapy for Age-Related Macular Degeneration (AMD): Anti-Angiogenic Activity of Fibulin-7 and its Fragments In Vivo
Author(s): T Ikeuchi, P Forcinito, S de Vega, J Amaral, I Rodrigez, E Arikawa-Hirasawa, Y Yamada

NIDCR
MOLBIO-13

Oral administration of a β-hydroxybutyrate ester regulates blood cholesterol in rats and humans
Author(s): MF Kemper, S Srivastava, MT King, K Clarke, RL Veech, RJ Pawlosky

NIAAA
MOLBIO-14
NCI
MOLBIO-15
NHLBI
MOLBIO-16
NIA
MOLBIO-17
NCI
MOLBIO-18

Isolation and Characterization of a TDP1 Inhibitory Peptide from the Marine Sponge Axinella sp
Author(s): LR Krumpe, S Sunassee, A Bermingham, C Marchand, KR Gustafson, Y Pommier, BR O'Keefe

NCI
MOLBIO-19

Exploring treatment strategies for FXS: high-throughput drug screens and the identification of potential biomarkers
Author(s): D Kumari, M Swaroop, A Bhattacharya, J Nadel, K Moulton, NM Zeak, A Glicksman, C Dobkin, DJ Brick, N Southall, W Huang, PH Schwartz, CB Smith, E Klann, W Zheng, K Usdin

NIDDK
MOLBIO-20
NCI
MOLBIO-22

Therapeutic efficacy of a peripherally restricted CB1R antagonist/AMPK activator in obesity/metabolic syndrome
Author(s): ZY Liu, R Cinar, M Iyer, T Jourdan, G Godlewski, G Szanda, J Liu, G Kunos

NIAAA
MOLBIO-23
NIDDK
MOLBIO-24
NCI
MOLBIO-25

The RNA topoisomerase Top3b is required for normal synapse structure and function in mice
Author(s): W Peng, Y Wang, J Sima, W Shen, M Mattson, W Wang

NIA
MOLBIO-26
NCI
MOLBIO-27

CK2 acts as a potent negative regulator of receptor-mediated insulin release from pancreatic beta-cells
Author(s): M Rossi, LF Barella, I Ruiz de Azua, W Sakamoto, L Zhu, Y Cui, A Butcher, AB Tobin, J Wess

NIDDK
MOLBIO-28
NICHD
MOLBIO-29

Nuclear Magnetic Resonance (NMR) Lipoprotein Profiles Suggest Higher Cardiovascular Disease Risk in Stressed Caregivers
Author(s): E Stoops, S Klagholz, L Yang, L Wehrlen, A Ross, R Shamburek, M Bevans

CC
MOLBIO-30

Identification of a novel inhibitor of 5-Lipoxygenase
Author(s): P Subramanian, E Mendez, SP Becerra

NEI
MOLBIO-31

Steroid receptors can facilitate the binding of the pioneer factor FoxA1 in breast cancer cell lines through a dynamic assisted loading (DynALoad) mechanism
Author(s): EE Swinstead, TB Miranda, V Paakinaho, DM Presman, S Baek, M Hawkins, T Karpova, D Ball, L Grøntved, GL Hager

NCI
MOLBIO-32
NIAAA
MOLBIO-33
NICHD
MOLBIO-34
NCI
MOLBIO-35

NHLBI Animal MRI Core
Author(s): SA Anderson

NHLBI
RSCHSUPP-1

Dietary intake patterns are consistent across seasons in a metropolitan population
Author(s): C Arango, RC Kelley, SG Miszewski, S Tryon, S Bernstein, K Zambell, MJ Amar, A Courville

CC
RSCHSUPP-2
CC
RSCHSUPP-3

Model-based research protocol design tools for enhanced study planning, operations management, and research data annotation, integration and reuse
Author(s): SW Bartlinski, RJ Woodrow, HM Hall, CJ Barnett, DM Varghese, S Xu, T Ahmed, KJ Footer, DB Parrish

NIAID
RSCHSUPP-4

Facile fluorine-18 labeling of serum albumins via the coupling of [18F]fluoronicotinic acid tetrafluorophenyl ester with albumin amine groups
Author(s): F Basuli, B Xu, O Vasalatiy, GL Griffiths, E Jagoda, M Green, J Seidel, P Choyke, R Swenson

NHLBI
RSCHSUPP-5
OD
RSCHSUPP-6

The Imaging Probe Development Center Makes All Types of Diagnostic Imaging Agents
Author(s): B Blackman, F Bhattacharyya, C Hitco, AC Opina, C Mushti, D Sail, ZD Shi, H Wu, B Xu, V Coble, K Lane, X Zhang, R Swenson

NHLBI
RSCHSUPP-7
NHLBI
RSCHSUPP-8
CC
RSCHSUPP-9

Using Data Visualizations to Advance Clinical Trial Data Analytics
Author(s): M Duvenhage, P Gumne, G Marlow, J Sun, K Newell, M Tartakovsky

NIAID
RSCHSUPP-10

Risk-Based Monitoring and Quality Management Plans: An Interdependent Relationship and Factors Influencing Plan Development
Author(s): J Farrell, A Adams, J Beeler, L Giebeig, D Shelley, S Simpson, B Baseler, J Pierson, S Vogel

NIAID
RSCHSUPP-11
OD
RSCHSUPP-12

The NIH Library Bioinformatics Support Program
Author(s): P Hanrahan, K Kavanaugh, C Kelley, Y Lu, D McDowell, M Pham, T Sisay, M Tanwar, L Young

OD
RSCHSUPP-13

Validation in a Resource Limited Environment – A Strategic Approach
Author(s): M Holdsworth, M Duvenhage, C Lassnoff, J Sun, K Newell, C Whalen, M Tartakovsky

NIAID
RSCHSUPP-14

Pharmacokinetic Evaluation of Potent Mutant IDH1 Inhibitors in Discovery Research
Author(s): EA Hughes, J Rohde, MI Davis, MB Boxer, X Xu, AQ Wang

NCATS
RSCHSUPP-15

Developing a library-based data visualization service
Author(s): DJ Joubert, L Federer, CW Belter, MA Davis, A Deardorff

OD
RSCHSUPP-16

NCI/CCR/LRBGE Optical Microscopy Core
Author(s): TS Karpova, DA Ball

NCI
RSCHSUPP-17
CC
RSCHSUPP-18

NIH Mouse Imaging Facility - a multi-modal preclinical animal imaging facility open to the NIH intramural research community
Author(s): BA Klaunberg, MJ Lizak, HD Morris, JP Munasinghe, DJ DesPres, VM Diaz, DR Donahue

NINDS
RSCHSUPP-19
NCI
RSCHSUPP-20

Building Quality into the Data Migration Process
Author(s): C Lassnoff, M Duvenhage, J Sun, C Whalen, M Tartakovsky

NIAID
RSCHSUPP-21
NIAID
RSCHSUPP-22

Extracellular vesicle analyses by nanoFACS
Author(s): A Morales-Kastresana, LM Jenkins, K McKinnon, TA Musich, T Demberg, M Terabe, JA Berzofsky, JC Jones

NCI
RSCHSUPP-23

Clinical Temperature Data Monitoring and Alerting in Remote Regions
Author(s): B Moyer, K Pomeroy, M Duvenhage, C Whalen, M Tartakovsky

NIAID
RSCHSUPP-24

In-vitro ADME metabolic stability profiling
Author(s): KLT Nguyen, KR Yu, X Xu

NCATS
RSCHSUPP-25
NIAID
RSCHSUPP-26
NLM
RSCHSUPP-27

Synthesis of 13C– Labeled Imaging Probes for Metabolic MRI Studies Using Hyperpolarization
Author(s): DS Sail, ACL Opina, S Matsumoto, S Kishimoto, O Vasalatiy, JL Meier, AH Kesarwala, JB Mitchell, MC Krishna, RE Swenson

NHLBI
RSCHSUPP-28
NCATS
RSCHSUPP-29
OD
RSCHSUPP-30

A Resource for Collaborative Biologics Development in the NIH Intramural Program: NIH–Pfizer CTI Partnership
Author(s): Sitta Sittampalam, Lili Portilla, Anna Rossoshek, Balki Balakrishnan, Nicol Spears, Geoff Spencer, Cindy McConnell, Chris Austin, Anton Simeonov

NCATS
RSCHSUPP-31
NLM
RSCHSUPP-32
NEI
RSCHSUPP-33
OD
RSCHSUPP-34
NINDS
RSCHSUPP-35

We're serious about monkey business
Author(s): KL Vaughan, D Sedlak, M Szarowicz, A Evans, E Tilmont, JA Mattison

OD
RSCHSUPP-36
NIAID
RSCHSUPP-37

The Imaging Probe Development Center (IPDC)makes imaging probes for the NIH intramural community and their collaborators
Author(s): H Wu, F Bhattacharyya, B Blackman, V Coble, C Hitko, K Lane, C Mushti, A Opina, N Raju, D Sail, Z Shi, O Vasalatiy, B Xu, X Zhang, R Swenson

NHLBI
RSCHSUPP-38

Automated Production of [18F]Fluoroglutamine for Tumor Imaging
Author(s): X Zhang, F Bhattacharyya, Z Shi, O Vasalatiy, B Xu, G Griffiths, P Choyke, R Swenson

NHLBI
RSCHSUPP-39

Clinical Research recruitment and you!
Author(s): C Alvarez-Mells, J Bartholomew, D Dominguez

OD
RSCHSUPP-40

Poster Session II

Thursday, September 17, 2015 — 12:00 p.m. – 1:30 p.m. — FAES Terrace

NIMHD
CANCER-1
NCI
CANCER-2
NIBIB
CANCER-3
NCI
CANCER-4
NCI
CANCER-5

LTβ receptor and NIK signaling activates the alternative NF-kB pathway and indures cell migration in head and neck squamous cell carcinoma
Author(s): Rita Das, Tsu-F Cheng, Jamie Coupar, A Saleh, XP Yang, S Carlson, S Cornelius, J Zhang, Carte Van Waes, Zhong Chen

NIDCD
CANCER-6

Profiling molecular changes in N,N-Dimethyl-p-toluidine-induced nasal cavity toxicity
Author(s): JK Dunnick, BA Merrick, G Flake, J Foley, A Brix, K Gerrish, KR Shockley

NIEHS
CANCER-7
NCI
CANCER-8
NCI
CANCER-9
NCI
CANCER-10

Fusion guided combination of external beam radiation with thermal ablation for liver tumors
Author(s): L Jiang, VP Krishnasamy, H Amalou, S Xu, D Citrin, R Miller, H Ning, BJ Wood

CC
CANCER-11

Using Irys® System,NanoChannel Array technology,to directly visualizing genomic information
Author(s): Y Jiang, S Bilke, RL Walker, JJ Waterfall, SS Davis, JL Lueders, V Larionov, P Meltzer

NCI
CANCER-12

Identification of Extracellular Vesicle Subsets with nanoFACS
Author(s): JC Jones, A Morales-Kastresana, JA Berzofsky

NCI
CANCER-13

Overcoming resistance mechanisms in a study of cabozantinib (C) plus docetaxel (D) and prednisone (P) in metastatic castrate-resistant prostate cancer (mCRPC)
Author(s): FH Karzai, RA Madan, MR Theoret, PM Arlen, J Strauss, G Chun, A Couvillon, N Harold, C Chen, NA Dawson, SM Steinberg, JB Trepel, JJ Wright, DK Price, JL Gulley, WD Figg, WL Dahut

NCI
CANCER-14
NHLBI
CANCER-15

Targeting the C1 domain of the Vav3 oncogene as a novel therapeutic approach
Author(s): JS Kelsey, T Geczy, NE Lewin, PM Blumberg

NCI
CANCER-16

Selective small molecule stabilization of G-quadruplex drives transcriptional regulation of MYC
Author(s): EC Leon, KM Felsenstein, LB Saunders, JK Simmons, S Zhang, A Michalowski, P Gareiss, BA Mock, JS Schneekloth

NCI
CANCER-17
NIEHS
CANCER-18

The novel p53 target Tumor Necrosis Factor-α-Induced Protein 8 variant 2 is increased in human cancers and can offset p53-dependent tumor suppression
Author(s): JM Lowe, T Nguyen, MA Resnick, SA Grimm, KA Gabor, SD Peddada, CW Anderson, D Menendez, MB Fessler

NIEHS
CANCER-19

Unveiling the role of C/EBPG as a Master Stress Response Regulator
Author(s): MK Mayekar, CJ Huggins, N Martin, KL Saylor, M Gonit, P Jailwala, M Kasoji, DC Haines, OA Quinones, PF Johnson

NCI
CANCER-20

ERalpha-induced C/EBPD inhibits SNAI2 expression and is a marker of good prognosis in breast cancer
Author(s): D Mendoza-Villanueva, K Balamurugan, R Ali, SR Kim, S Sharan, R Johnson, A Merchant, C Caldas, G Landberg, E Sterneck

NCI
CANCER-21

Initiation and progression of UV-induced melanocytic lesions in a mouse model of melanoma
Author(s): HT Michael, CP Day, A Michalowski, MR Zaidi, PS Meltzer, G Merlino

NCI
CANCER-22
FDA/CBER
CANCER-23

KLF4 dependent smooth muscle cell plasticity promotes metastasis
Author(s): M Murgai, AJ Giles, C Reid, M Kasai, RN Kaplan

NCI
CANCER-24

Frequent gain-of-function CCR4 mutations in Adult T-cell Leukemia/Lymphoma
Author(s): M Nakagawa, R Schmitz, W Xiao, CK Goldman, W Xu, Y Yang, X Yu, TA Waldmann, LM Staudt

NCI
CANCER-25
NCI
CANCER-26
NCI
CANCER-27
NCI
CANCER-28

High-throughput screening as a tool to identify novel therapies for treatment of bladder cancer: a proof of principle study
Author(s): R Railkar, K Lewi, A Nair, SJ Brancato, I Hsu, Q Li, X Zhang, R Guha, A Apolo, D Theodorescu, C Thomas, M Ferrer, PK Agarwal

NCI
CANCER-29

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma based on mRNA, microRNA and DNA Methylation Biomarkers
Author(s): AI Robles, E Arai, EA Mathe, H Okayama, AJ Schetter, D Petersen, ED Bowman, R Noro, JA Welsh, DC Edelman, HS Stevenson, Y Wang, A Haugen, PS Meltzer, J Yokota, Y Kanai, CC Harris

NCI
CANCER-30
NCI
CANCER-31

Aberrant uterine SIX1 expression may promote uterine adenocarcinoma following neonatal xenoestrogen exposure
Author(s): AA Suen, WN Jefferson, E Padilla-Banks, CE Woods, VL Bae-Jump, CJ Williams

NIEHS
CANCER-32

Thermal ablation of metastatic adrenocortical carcinoma: long-term results
Author(s): GM Varano, L Jiang, VP Krishnasamy, N Jain, H Amalou, M Edgerly, M Velarde, N Abi Jaoudeh, AM Venkatesan, EB Levy, A Fojo, BJ Wood

CC
CANCER-33

Nitric oxide enhances tumor progression and disease aggressiveness in pancreatic cancer
Author(s): J Wang, P He, MM Gaida, S Yang, A Schetter, J Gaedcke, BM Ghadimi, T Ried, HG Yfantis, DH Lee, JM Weiss, J Stauffer, N Hanna, HR Alexander, SP Hussain

NCI
CANCER-34

Small cell lung cancer growth is inhibited by miR-342 and its target gene IA-2
Author(s): H Xu, T Cai, G Carmona, L Abuhatzira, AL Notkins

NIDCR
CANCER-35

A Novel MIF-driven Signaling Drives Disease Aggressiveness by Targeting NR3C2 in Pancreatic Ductal Adenocarcinoma
Author(s): S Yang, P He, J Wang, A Schetter, W Tang, N Funamizu, K Yanaga, T Uwagawa, AR Satoskar, J Gaedcke, M Bernhardt, BM Ghadimi, MM Gaida, F Bergmann, J Werner, T Ried, N Hanna, HR Alexander, SP Hussain

NCI
CANCER-36

Altered inflammatory and death pathways in head and neck cell lines model genomic and expression signatures identified in The Cancer Genome Atlas
Author(s): X Yang, H Cheng, A Saleh, S Cornelius, E Guven-Maiorov, O Keskin, A Gursoy, R Nussinov, C Van Waes, Z Chen

NIDCD
CANCER-37
NCI
CANCER-38
NHLBI
CANCER-39

a Microarray-based approach for the development of RNA-binding small molecules with anti-HIV activity
Author(s): FA Abulwerdi, R van Duyne, J Sztuba-Solinska, EO Freed, SFJ Le Grice, JS Schneekloth Jr

NCI
CHEMBIO-1
NCI
CHEMBIO-2

Drug Combination Screening for Ewing’s Sarcoma
Author(s): MI Davis, R Guha, KM Wilson, M Gormally, P Shinn, X Zhang, S Michael, C McKnight, T Mierzwa, P Meltzer, F Arnaldez, L Helman, C Thomas

NCATS
CHEMBIO-3

Multivalent Display on Synthetic PNA Scaffolds
Author(s): KM George Rosenker, AV Dix, DH Appella

NIDDK
CHEMBIO-4
NCI
CHEMBIO-5

Dermal uptake of Tetrabromobisphenol A (TBBPA) by female Wistar Han rat or human skin
Author(s): GA Knudsen, KL McIntosh, JM Sanders, MF Hughes, LS Birnbaum

NCI
CHEMBIO-6

Profiling the role of non-enzymatic acetylation in cancer
Author(s): RA Kulkarni, TT Zengeya, AM Roberts, JL Meier

NCI
CHEMBIO-7
NCI
CHEMBIO-8
NCI
CHEMBIO-9
NCI
CHEMBIO-10
NCI
CHEMBIO-11

Loss of NLZ2 Expression Results in Coloboma and Abnormal RPE Development in Mouse
Author(s): E Boobalan, RP Alur, L Dong, G Shih, F Onojafe, O Memon, K Bharti, BP Brooks

NEI
DEVBIO-1
NHLBI
DEVBIO-2

Fascinating Femurs!! A 6-micron look into mouse bone structure
Author(s): DR Donahue, VM Diaz, BA Klaunberg

NINDS
DEVBIO-3
NHGRI
DEVBIO-4
NCI
DEVBIO-5

A Novel Role for Nonmuscle Myosin II-A in Sperm Development
Author(s): CB Lerma Cervantes, K Tokuhiro, N Billington, A Wang, Y Zhang, MA Conti, MJ Kelley, MP Daniels, JR Sellers, J Dean, RS Adelstein

NHLBI
DEVBIO-6
NHLBI
DEVBIO-7
NICHD
DEVBIO-8
NIDDK
DEVBIO-9

PI3K/Akt signaling regulates ciliogenesis initiation via Rab11-effector vesicular trafficking switch
Author(s): V Walia, C Insinna (Kettenhofen), Q Lu, S Specht, CJ Westlake

NCI
DEVBIO-10
NHLBI
DEVBIO-11

Tissue-localized macrophages is the origin of pericytes in mouse embryonic skin vasculature
Author(s): T Yamazaki, A Nalbandian, S Abdelazim, Y Uchida, W Li, TD Arnold, Y Kubota, M Ema, Y Mukouyama

NHLBI
DEVBIO-12

Seasonal dynamics of Plasmodium falciparum gametocyte carriage a highly seasonal transmission area
Author(s): Y Adomako-Ankomah, M Chenoweth, S Doumbia, D Konate, M Doumbouya, AS Keita, D Nikolaeva, JM Anderson, G Tullo, RM Fairhurst, K Miura, M Diakite, CA Long

NIAID
MICROBIO-1

Inactivated Shigella as Effective Vaccines and Vaccine Vectors
Author(s): I Albino-Flores, S Filippova, C Marsh, S Stibitz, M Osorio

FDA/CBER
MICROBIO-2

Anopheline vectors drive selection of Plasmodium falciparum Pfs47
Author(s): GE Canepa, A Molina-Cruz, C Barillas-Mury

NIAID
MICROBIO-3
NCI
MICROBIO-4
NICHD
MICROBIO-5

Biofilms cause recalcitrance of staphylococcal joint infection to antibiotic treatment
Author(s): SS Dastgheyb, AE Villaruz, KL Le, VY Tan, AC Duong, SS Chatterjee, GY Cheung, HS Joo, J Parvizi, IM Shapiro, NJ Hickok, M Otto

NIAID
MICROBIO-6

Experimentally induced visceral pain, variation in the microbiome, and host gene expression in irritable bowel syndrome
Author(s): NH Fourie, D Wang, PA Smyser, SK Abey, EG Ferguson, LB Sherwin, B Rahim-Williams, WA Henderson

NINR
MICROBIO-7
NINR
MICROBIO-8

Liver Regeneration and Fibrosis are Concurrently but Independently Driven by Type-2 Immunity
Author(s): RL Gieseck, T Ramalingam, K Hart, K Vannella, WY Lu, S Ferreira-Gonzalez, SJ Forbes, L Vallier, TA Wynn

NIAID
MICROBIO-9
FDA/CBER
MICROBIO-10

Engineering Bacteriophage To Target KPC+ K. pneumoniae
Author(s): J Jensen, D Court, A Parks

NCI
MICROBIO-11
CC
MICROBIO-12
NICHD
MICROBIO-13
NICHD
MICROBIO-14

Proteomic predictors of IgG responses to natural Plasmodium falciparum infection
Author(s): EW Liu, J Skinner, A Ongoiba, B Traore, A Jain, S Li, K Kumar, D Narum, S Paul, B Peters, P Felgner, P Crompton

NIAID
MICROBIO-15
NCI
MICROBIO-16

TBRAT: Tuberculosis Regulatory Network Analysis Tool
Author(s): V Nagarajan, J Ning, A Gabrielian, D Hurt

NIAID
MICROBIO-17

SIVagm from African green monkeys can use non-CCR5 entry pathways in vitro and ex vivo
Author(s): NE Riddick, RM Goeken, S Whitted, JM Brenchley, VM Hirsch

NIAID
MICROBIO-18
NCI
MICROBIO-19

Evaluation of interspecies plasmid transfer and comparison with hospital epidemiology data
Author(s): RA Weingarten, CA Hardiman, AJ Mathers, JP Dekker, S Conlan, TN Palmore, JA Segre, KM Frank

CC
MICROBIO-20
NCI
MICROBIO-21

The CEBPD transcription factor: a signaling hub for promotion of cancer cell stemness
Author(s): K Balamurugan, DY Mendoza, G Summers, S Sharan, E Sterneck

NCI
STEMCELL-1

Role for the Melanocortin 3 Receptor in determining mesenchymal stem cell fate
Author(s): JY Jun, B Lee, AS Seo, Y Lee, J Koo, S Jung, JA Yanovski

NICHD
STEMCELL-2
CC
STEMCELL-3
CC
STEMCELL-4

COMPARISON OF THE ABILITY OF IPSCs INTO GERM CELLS
Author(s): S Park, J Yu, AH DeCherney, EF Wolff

NICHD
STEMCELL-5
NEI
STEMCELL-6
CC
STEMCELL-7
NINDS
STEMCELL-8
NIBIB
STEMCELL-9

Cxcr4 haploinsufficiency enhances hematopoietic stem cell engraftment
Author(s): E Yim, M Siwicki, J-L Gao, PM Murphy

NIAID
STEMCELL-10

Proteomic profiling of the macrophage secretome upon Toll-like receptor stimulation
Author(s): M Koppenol-Raab, V Sjoelund, B Dutta, Z Benet, I Fraser, A Nita-Lazar

NIAID
SYSBIO-1

Assessing the utility of gadolinium-based contrast agents administered by the intravenous and the intraperitoneal route
Author(s): JS Kumar, VM Diaz, JP Munasinghe, MD Hall, MM Gottesman, BA Klaunberg

NINDS
SYSBIO-2

SBR-Blood: Systems Biology Repository for Hematopoietic Cells
Author(s): J Lichtenberg, EF Heuston, T Mishra, CA Keller, RC Hardison, DM Bodine

NHGRI
SYSBIO-3

Targeted proteomics-driven computational modeling of macrophage S1P chemosensing
Author(s): NP Manes, BR Angermann, M Koppenol-Raab, E An, VH Sjoelund, J Sun, M Ishii, RN Germain, M Meier-Schellersheim, A Nita-Lazar

NIAID
SYSBIO-4

Analysis of cellular heterogeneity in activated macrophages reveals hidden modes of state-specific gene regulation
Author(s): AJ Martins, M Narayanan, T Prustel, B Fixsen, Y Lu, RA Gottschalk, C Pfannkoch, W Lau, K Wendelsdorf, JS Tsang

NIAID
SYSBIO-5
NIDDK
SYSBIO-6

Genome-wide approaches elucidate the role of Ikaros in macrophage LPS responses
Author(s): KS Oh, RA Gottschalk, SJ Baek, GL Hager, MH Sung, ID Fraser

NIAID
SYSBIO-7

Discovering new pathways in the heart during hypoxia: Proteomic approaches to identify the cardiac prolyl hydroxalome and to analyze protein stability
Author(s): A Stoehr, AM Evangelista, Y Yang, S Patel, A Aponte, G Wang, J Boylston, Y Lin, M Gucek, J Zhou, E Murphy

NHLBI
SYSBIO-8

Poster Session III

Thursday, September 17, 2015 — 3:30 p.m. – 5:00 p.m. — FAES Terrace

Resin-embedded multicycle imaging of cells and isolated plasma membranes
Author(s): BL Busse, L Bezrukov, P Blank, J Zimmerberg

NICHD
CELLBIO-1
NICHD
CELLBIO-2
NINR
CELLBIO-3
NIAAA
CELLBIO-4
NIDDK
CELLBIO-5

Targeted reduction of let-7a miRNA increases fetal hemoglobin in human adult erythroblasts
Author(s): JF de Vasconcellos, C Byrnes, YT Lee, M Kaushal, JM Allwardt, A Rabel, JL Miller

NIDDK
CELLBIO-6
NHLBI
CELLBIO-7
CC
CELLBIO-8
NCATS
CELLBIO-9
NHGRI
CELLBIO-10

The isolation, proteomic analysis and function of Dictyoselium exosomes
Author(s): PW Kriebel, L Jenkins, K Narayan, L Liu, CA Parent

NCI
CELLBIO-11
NHLBI
CELLBIO-12
NICHD
CELLBIO-13

Importance of methodological standardization for the ektacytometric measures of red blood cell deformability in sickle cell anemia
Author(s): N Parrow, C Renoux, C Faes, P Joly, M Hardeman, J Tisdale, M Levine, N Garnier, Y Bertrand, K Kebaili, D Cuzzubbo, G Cannas, C Martin, V Pialoux, P Connes

NIDDK
CELLBIO-14

BORC, a Multisubunit Complex that Regulates Lysosome Positioning
Author(s): J Pu, C Schindler, R Jia, M Jarnik, P Backlund, JS Bonifacino

NICHD
CELLBIO-15

Plk1 is required for nuclear envelope breakdown and single nucleus formation in C. elegans embryonic cells
Author(s): MM Rahman, M Munzig, K Kaneshiro, B Lee, S Strome, T Muller-Reichert, O Cohen-Fix

NIDDK
CELLBIO-16

Overexpression of β6-tubulin disorganizes the microtubule network of skeletal muscle fibers
Author(s): D Randazzo, JJ Belanto, DM Talsness, A Kenea, JM Ervasti, E Ralston

NIAMS
CELLBIO-17

EphrinB2 controls vessel pruning through STAT1-JNK3 signalling
Author(s): O Salvucci, H Ohnuki, D Maric, X Hou, X Li, SO Yoon, M Segarra, CG Eberhart, A Acker-Palmer, G Tosato

NCI
CELLBIO-18
NIDDK
CELLBIO-19
NICHD
CELLBIO-20

Protein O-glycosylation in the adult kidney
Author(s): E Tian, S Spitznagel, MC Malicdan, M Huizing, LA Tabak, KG Ten Hagen

NIDCR
CELLBIO-21
NIDCR
CELLBIO-22
NHLBI
CELLBIO-23
NCI
CELLBIO-24

Endothelial expression of endothelin receptor A in the systemic capillary leak syndrome
Author(s): Z Xie, AC Sek, K Terai, LM Long, C Nelson, AZ Dudek, KM Druey

NIAID
CELLBIO-25
NIAAA
CELLBIO-26
NHGRI
CELLBIO-27
NIDDK
CELLBIO-28

FLJ11286 (IRAV) is a Novel Interferon Stimulated Gene with Antiviral Activity Against Dengue
Author(s): CA Balinsky, H Schmeisser, S Ganesan, T Jin, K Singh, KC Zoon

NIAID
DIR-1

Modelling Evolutionarily Conserved Human Insulin Receptor Mutations in the Worm
Author(s): D Bulger, T Fukushige, R Semple, J Hanover, M Krause

NIDDK
DIR-2
NCCIH
DIR-3

Pre-transplant predictors of one year weight gain after kidney transplantation
Author(s): AK Cashion, DK Hathaway, A Stanfill, F Thomas, JD Ziebarth, Y Cui, PA Cowan, J Eason

NINR
DIR-4
NIA
DIR-5

Structural changes in blood platelet activation visualized by scanning transmission electron tomography
Author(s): RD Leapman, JD Hoyne, GN Calco, BC Kuo, MA Aronova, Q He, G Zhang, ID Pokrovskaya, JA Kamykowski, AA Prince

NIBIB
DIR-6

Soluble Epoxide Hydrolase Regulates Macrophage Phagocytosis and Lung Bacterial Clearance of Streptococcus Pneumoniae
Author(s): H Li, JA Bradbury, ML Edin, JP Graves, A Gruzdev, J Cheng, SL Hoopes, LM DeGraff, MB Fessler, S Garantiziotis, SH Schurman, DC Zeldin

NIEHS
DIR-7

Developing Science to Underpin NIH Peer Review
Author(s): R Nakamura, D Luckett, MA Guadagno, A Rubinstein, A Vancea, A Manning, C Dumais, R Etcheberrigaray, MC Chen

OD
DIR-8

Generation of Chimeric P-glycoprotein for Functional and Structural Investigations
Author(s): KM Pluchino, JK Moen, MD Hall, L Esser, F Zhou, EE Chufan, SV Amubdkar, Di Xia, MM Gottesman

NCI
DIR-9
NINDS
DIR-10

A new molecular cause of gigantism
Author(s): CA Stratakis, F Faucz, GP Trivellin

NICHD
DIR-11

X-linked retionoschisis: Retinal biology, synaptic rescue and human gene transfer clinical trial
Author(s): PA Sieving, Y Zeng, C Vijayasarathy, C Cukras, H Wiley, A Turriff, P Colosi, S Hiriyanna, R Bush, Z Wu, D Marangoni, J Ou, W Li, B Jeffrey, P Sherry, L Wei

NEI
DIR-12

Osteogenesis imperfecta causes defects in tooth development and periodontal function in four mouse models
Author(s): H Xu, BL Foster, A Coulter, W Cabral, A Barnes, A Boskey, J Shapiro, R Morello, J Marini, MJ Somerman

NIDCR
DIR-13

Deletion of the IFN-gamma 3’ UTR AU-rich element results in autoimmune cholangitis in female C57/BL6 mice
Author(s): H Bae, JC Valencia, DL Hodge, T Back, M Karwan, D Feng, B Gao, O Park, K Tsuneyama, PS Leung, ME Gershwin, HA Young

NCI
IMMUNO-1
NIAID
IMMUNO-2

Spontaneous ocular autoimmunity in the absence of Th1 and Th17 effector cytokines
Author(s): SJ Bing, R Horai, WP Chong, P Silver, Y Jittayasothorn, CC Chan, R Caspi

NEI
IMMUNO-3

Long-lasting memory responses and rapid recall of immune responses induced by the HIV-1 Conserved Element DNA Vaccine in rhesus macaques
Author(s): Y Cai, V Kulkarni, A Valentin, E Ramirez, C Alicea, X Hu, M Rosati, GN Pavlakis, BK Felber

NCI
IMMUNO-4

Polycystic liver disease is suppressed by IL-4/IL-13 and TGF-beta signaling
Author(s): DA Cantu, K Kindrachuk, L Borthwick, D Donahue, D Morris, D Dorwood, B Klaunberg, T Ramalingam, S White, R Thompson, TA Wynn

NIAID
IMMUNO-5

T cell oxygen sensing is required for suppression of pulmonary effector responses
Author(s): D Clever, M Askenase, R Roychoudhuri, Y Belkaid, NP Restifo

NCI
IMMUNO-6
FDA/CBER
IMMUNO-7

Impaired Chemokine Production and Neutrophil Recruitment in CARD9-Deficient Mice and Humans with Brain Fungal Infection
Author(s): RA Drummond, AL Collar, M Swamydas, JK Lim, AP Hsu, CM Mikelis, SR Rose, EMN Ferre, L Yockey, K Lemberg, HS Kuehn, SD Rosenzweig, X Lin, P Chittiboina, TH Belhorn, ET Weiner, ML Hernandez, TM Hohl, DB Kuhns, MS Lionakis

NIAID
IMMUNO-8
NINR
IMMUNO-9

Smith-Lemli-Opitz Syndrome reveals requirement for sterol biosynthesis in the innate immune response
Author(s): KA Gabor, CA Wassif, PR Bushel, MW Henderson, FD Porter, MB Fessler

NIEHS
IMMUNO-10

Contextual Control of TLR-induced Responses by Divergent Signaling Thresholds
Author(s): RA Gottschalk, AJ Martins, BR Angermann, B Dutta, CE Ng, S Uderhardt, JS Tsang, IDC Fraser, M Meier-Schellersheim, RN Germain

NIAID
IMMUNO-11

Neutrophil recruitment during Leishmania infection: The role of sand fly salivary proteins
Author(s): AB Guimaraes-Costa, X Wen, A Carvalho, C Meneses, J Brzostowski, J Valenzuela, F Oliveira

NIAID
IMMUNO-12

Immune Modulation of NAFLD progression to NASH and Hepatic Fibrosis in Obesity
Author(s): KM Hart, RL Gieseck, LA Borthwick, KM Vannella, RW Thompson, S White, JC Sciurba, TR Ramalingam, TA Wynn

NIAID
IMMUNO-13

Neutrophil-mediated mechanisms of drug-induced autoimmunity
Author(s): JA Irizarry-Caro, C Carmona-Rivera, E Novakovich, V Subramanian, P Thompson, MJ Kaplan, PC Grayson

NIAMS
IMMUNO-14
NIAID
IMMUNO-15
NHLBI
IMMUNO-16
USUHS
IMMUNO-17
NEI
IMMUNO-18

Heterozygous Mutations in IKAROS in Patients with Progressive Loss of B Cells and Hypogammaglobulinemia
Author(s): HS Kuehn, JE Niemela, J Stoddard, S Ganesan, K Lemberg, J Monsale, S Rampertaap, A Agharahimi, A Hussey, TA Fleisher, SD Rosenzweig

CC
IMMUNO-19
NIAID
IMMUNO-20
NIA
IMMUNO-21

Combining anti-CTLA4 with RG7787, an Immunotoxin targeting Mesothelin, Promotes Tumor Eradication
Author(s): J Leshem, L Xiu-fen, T Bera, M Terabe, JA Berzofsky, I Pastan

NCI
IMMUNO-22
NIAID
IMMUNO-23
NIBIB
IMMUNO-24
NIAID
IMMUNO-25

Innate Immunity, Arterial Inflammation, and Vascular Stiffness in Patients with Systemic Lupus Erythematosus
Author(s): MM Purmalek, S Sakhardande, Y Temesgen-Oyelakin, A Fike, T Salahuddin, B Natarajan, Z Manna, E Joyal, S Hasni, N Mehta, MJ Kaplan

NIAMS
IMMUNO-26

Quantitative imaging of long-lived plasma cells in the bone marrow
Author(s): AJ Radtke, N Riteau, M Garmendia-Cedillos, T Pohida, RN Germain

NIAID
IMMUNO-27

Generation of CD40 mutant mice by CRISPR-Cas9 Technology
Author(s): LE Rivera Hiraldo, J Chiang, R Hodes

NCI
IMMUNO-28
NIAID
IMMUNO-29

Lupus oxidized high density lipoprotein promotes macrophage inflammation by blocking ATF3 activity
Author(s): CK Smith, SM Gordon, A Vivekanandan-Giri, MP Playford, N Mehta, AT Remaley, S Pennathur, MJ Kaplan

NIAMS
IMMUNO-30
NEI
IMMUNO-31
NINDS
IMMUNO-32
NEI
IMMUNO-33
NIAID
IMMUNO-34

Dendritic and epithelial cell crosstalk in the lung: the impact of cell-specific Myd88 expression on consequent immune response to allergens
Author(s): SY Thomas, GS Whitehead, KM Gowdy, M Takaku, X Xu, JM Ward, K Nakano, H Nakano, P Wade, DN Cook

NIEHS
IMMUNO-35
NICHD
IMMUNO-36
NIAID
IMMUNO-37

Potent Immunotherapeutic Effects of Anti-PD-L1 in an Orthotopic Murine Bladder Tumor Model
Author(s): AJ Vandeveer, JK Fallon, KW Hance, Y Lan, H Sabzevari, J Schlom, JW Greiner

NCI
IMMUNO-38

IRAK1 as a shunt in multi-ligand signaling through Toll-like receptors
Author(s): SJ Vayttaden, M Smelkinson, Z Benet, RA Gottschalk, RN Germain, MK Meier-Schellersheim, RR Varma, IDC Fraser

NIAID
IMMUNO-39

TCF1 is required for the T follicular helper (TFH) cell response to viral infection
Author(s): T Wu, H Shin, E Moseman, Y Ji, B Huang, J Sen, L Berg, L Gattinoni, D McGavern, P Schwartzberg

NHGRI
IMMUNO-40
FDA/CBER
IMMUNO-41

Poster Session IV

Friday, September 18, 2015 — 12:00 p.m. – 1:30 p.m. — FAES Terrace

Characterization of a human model of chronic-heavy-intermittent-drinking
Author(s): LR Arcurio, ML Schwandt, X Zhu, RM Momenan, L Leggio

NIAAA
BEHAV-1

Nocturnal wakefulness is associated with next-day suicidal ideation in Major Depression and Bipolar Disorder
Author(s): ED Ballard, JL Vande Voort, RA Bernert, DA Luckenbaugh, EM Richards, MJ Niciu, ML Furey, WC Duncan, CA Zarate

NIMH
BEHAV-2

Promoting Innovation: NIH Diversity Catalysts develop testable strategies to enhance diversity at NIH
Author(s): E Billingslea, AF Davis, A Han, J Lun, I Avila, HA Valantine

OD
BEHAV-3
NIAAA
BEHAV-4

Sleep disturbance in individuals with alcohol dependence: findings from an exploratory mixed methods study
Author(s): AT Brooks, M Krumlauf, ML Schwandt, VA Ramchandani, GR Wallen

CC
BEHAV-5

Face-to-Face Interactions between Mothers and Infants: A Predictor of Social Skills in Later Life
Author(s): AM Dettmer, A Paukner, SK Kaburu, EA Simpson, SJ Suomi

NICHD
BEHAV-6
NIMHD
BEHAV-7

A Human Laboratory Study of Baclofen in Alcoholism: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial
Author(s): M Farokhnia, J Amodio, J Bollinger, T Lionetti, D Spero, LA Farinelli, MR Lee, ML Schwandt, L Leggio

NIAAA
BEHAV-8
NINR
BEHAV-9
NIMH
BEHAV-10

A pilot study of the monetary incentive delay task with an aversive event: effects on anxiety
Author(s): JL Gowin, R Momenan, K Mathur, M Ernst, VA Ramchandani

NIAAA
BEHAV-11

Anxiety: A correlate of persistent sleep disturbance in individuals recovering from alcohol dependence
Author(s): MC Krumlauf, AT Brooks, L Yang, VA Ramchandani, ML Schwandt, GR Wallen

CC
BEHAV-12
NHGRI
BEHAV-13
NIMH
BEHAV-14
NIAAA
BEHAV-15
NIAAA
BEHAV-16

Incorporating mobile health (mhealth) technology for monitoring physical activity and dietary intake into a community-based health and needs assessment: The Washington D.C. Cardiovascular Health and Needs Assessment
Author(s): LR Yinging, JN Saygbe, GR Wallen, AT Brooks, M Peters-Lawrence, JL Henry, VM Mitchell, DM Sampson, TD Johnson, KL Wiley Jr, AP Graham, LA Graham, AJ Johnson, TM Powell-Wiley

NHLBI
BEHAV-17

Following the life course of BRCA1/2-mutation positive women: A qualitative follow-up study
Author(s): JL Young, A Werner-Lin, R Mueller, MH Greene, NB Epstein, K Roy

NCI
BEHAV-18

Facial plethora: modern technology for quantifying an ancient clinical sign and its use in Cushing syndrome
Author(s): A Afshari, Y Ardeshirpour, MB Lodish, E Gourgari, N Sinaii, M Keil, E Belyavskaya, C Lyssikatos, FA Chowdhry, V Chernomordik, AA Anderson, TA Mazzuchi, A Gandjbakhche, CA Stratakis

NICHD
BIOENG-1

Biomarkers of brain development in Early Childhood: a pilot study using functional near infrared spectroscopy
Author(s): AA Anderson, E Smith, V Chernomordik, F Chowdhry, NS Karamzadeh, A Thurm, A Gandjbakhche

NICHD
BIOENG-2
NCI
BIOENG-3
CC
BIOENG-4
NIBIB
BIOENG-5
NINDS
BIOENG-6

Biomedical Engineering and Physical Science Shared Resource
Author(s): HS Eden, AJ Balbo, EK Dimitriadis, AM Gorbach, HR Kalish, NY Morgan, G Zhang

NIBIB
BIOENG-7
NHLBI
BIOENG-8
NIBIB
BIOENG-9
FDA/CBER
BIOENG-10
CC
BIOENG-11

Five Year Review of Size and Age Specific CT Radiation Exposures
Author(s): WC Kovacs, J Yao, LR Folio, RM Summers

CC
BIOENG-12
NIBIB
BIOENG-13
CC
BIOENG-14
CC
BIOENG-15
NIDDK
BIOENG-16
NIBIB
BIOENG-17

In Vivo Albumin Labeling for Positron Emission Tomography
Author(s): G Niu, L Lang, DO Kiesewetter, X Chen

NIBIB
BIOENG-18

AFM study of HIV-Tat aggregation
Author(s): AL Popescu Hategan, EK Dimitriadis, E Karnaukhova, A Nath

NINDS
BIOENG-19

DeepOrgan: Multi-level Deep Convolutional Networks for Automated Pancreas Segmentation
Author(s): HR Roth, L Lu, A Farag, H-C Shin, J Liu, E Turkbey, RM Summers

CC
BIOENG-20
NCI
BIOENG-21

Leveraging Mid-Level Semantic Boundary Cues for Automated Lymph Node Detection
Author(s): A Seff, L Lu, A Barbu, HR Roth, HC Shin, RM Summers

CC
BIOENG-22

Interleaved Text/Image Deep Mining on a Large-Scale Radiology Image Database
Author(s): H-C Shin, L Lu, L Kim, A Seff, J Yao, RM Summers

CC
BIOENG-23

Multi-Atlas Segmentation with Joint Label Fusion of Compression Fractured Vertebrae on CT
Author(s): Y Wang, J Yao, HR Roth, J Liu, JE Burns, RM Summers

CC
BIOENG-24
NIBIB
BIOENG-25
NIBIB
BIOENG-26
NHLBI
GEN-1
NIAMS
GEN-2

Multi-modal imaging analyses of A-kinase anchor protein 13 (Akap13) conditional knockout mice
Author(s): KM Baig-Ward, SA Anderson, SL Mumford, VM Diaz, CW Quaglieri, X Wu, T Chu, BA Klaunberg, AH DeCherney, JH Segars

NICHD
GEN-3

The evolutionary dynamics of meiotic recombination initiation in mice
Author(s): K Brick, F Smagulova, Y Pu, G Petukhova, RD Camerini-Otero

NIDDK
GEN-4
NLM
GEN-5

Characterization of genomic alterations in HPV-negative and HPV-positive HNSCC cell lines with high throughput whole exome DNA and transcriptome RNA sequencing
Author(s): H Cheng, X Yang, H Si, A Saleh, J Coupar, RL Ferris, WG Yarbrough, ME Prince, TE Carey, C Van Waes, Z Chen

NIDCD
GEN-6

An intronic indel confers melanoma risk through PARP1 expression regulation
Author(s): J Choi, M Makowski, T Zhang, M Law, C Sutherland, M Kovacs, W Kim, H Parikh, L Aoude, M Gartside, J Trent, L Hurley, M Vermeulen, S Macgregor, N Hayward, M Xu, K Brown

NCI
GEN-7
NIDDK
GEN-8

The melanocortin 3 receptor C17A + G241A haplotype is associated with lower serum triglycerides and reduced lean mass in obese African American adults
Author(s): N Dedhia, A Davis, A Demidowich, D Koutzoumis, R Roberson, O Galescu, JY Jun, D Taylor-Douglas, S Armaiz, S Brady, JA Yanovski

NICHD
GEN-9

Genetic and epigenetic signatures of gene regulation specific to type 2 diabetes-relevant tissues
Author(s): JP Didion, SCJ Parker, BN Wolford, JR Huyghe, R Welch, MR Erdos, PS Chines, N Narisu, LJ Scott, ML Stitzel, M Boehnke, FS Collins

NHGRI
GEN-10
NICHD
GEN-11

Experimentally induced visceral pain, variation in the microbiome, and host gene expression in irritable bowel syndrome
Author(s): NH Fourie, D Wang, SK Abey, EG Ferguson, LB Sherwin, B Rahim-Williams, WA Henderson

NINR
GEN-12
NEI
GEN-13
NEI
GEN-14

Analysis of a histiocytic sarcoma locus – canine’s utility for fetching candidates
Author(s): SF Gilbert, HG Parker, AL Shearin, EA Ostrander

NHGRI
GEN-15

A new mouse model of type 2 Gaucher disease
Author(s): A Gonzalez, B Berhe, E Sidransky, N Tayebi

NHGRI
GEN-16

Unraveling the genetics of scleroderma in African-Americans
Author(s): P Gourh, F Boin, E Remmers, J Mullikin, C Derk, R Domsic, H Gladue, H Gladue, J Gordon, M Mayes, L Saketkoo, E Schiopu, V Shanmugam, R Silver, V Steen, M Trojanowski, J Varga, C Rotimi, F Wigley, D Kastner

NIAMS
GEN-17

Genetic, Epigenetic and Molecular Sensitivity Landscape of Pediatric Rhabdomyosarcoma
Author(s): BE Gryder, HC Chou, ME Yohe, YK Song, R Patidar, S Li, S Sindiri, A Cleveland, H Liao, X Wen, L Mathews-Griner, X Zhang, R Guha, P Shinn, M Ferrer, C Thomas, J Shern, J Khan

NCI
GEN-18
NHGRI
GEN-19

Mutations in MGAT5B affect the complex N-linked glycans in a patient with a neuromuscular phenotye
Author(s): IJ Hardee, ME Hackbarth, M Davids, MS Kane, M Hee, WA Gahl

NHGRI
GEN-20
NHGRI
GEN-21

Precise Mnase-Sequencing of Mouse Cells Reveals Distinct Nucleosome Organization at Active Promoters
Author(s): TA Johnson, RV Chereji, DA Stavreva, MJ Guertin, GL Hager, DJ Clark

NCI
GEN-22
NEI
GEN-23

A protein glycosylation screen to diagnose rare genetic disorders and unravel disease mechanisms
Author(s): MS Kane, M Davids, X Li, M Raihin, M He, WA Gahl, CF Boerkoel

NHGRI
GEN-24

Premature menopause and hematologic neoplasms in xeroderma pigmentosum patients: An unidentified feature of premature aging
Author(s): SG Khan, JJ DiGiovanna, D Tamura, M Merideth, J Ferrell, D Angra, KH Kraemer

NCI
GEN-25
NCI
GEN-26

The Trans-NIH RNAi screening facility
Author(s): MA Lal-Nag, N Slepushkina, DJ Fernandez, K Mazan-Mamczarz, S Chakka, J Fu, C Klumpp-Thomas, E Buehler, A Simeonov, N Caplen

NCATS
GEN-27
NLM
GEN-28
NIDDK
GEN-29
NICHD
GEN-30

Linkage analyses reveals significant association for myopia
Author(s): AM Musolf, CL Simpson, F Murgia, L Portas, JE Bailey-Wilson, D Stambolian

NHGRI
GEN-31
NIAMS
GEN-32
NIAAA
GEN-33

Thyroid Hormone Receptor α1 Mutants Impair Erythropoiesis
Author(s): SM Park, JW Park, CR Han, Li Zhao, D Bodine, SH Cheng

NCI
GEN-34
NIDDK
GEN-35

Inter-species differences in male meiotic recombination initiation
Author(s): F Pratto, K Brick, J Cloutier, B Davies, P Donnelly, RD Camerini-Otero

NIDDK
GEN-36
NIDDK
GEN-37

The connectome in the human brain: defining its heritability and association with ADHD
Author(s): GP Sudre, T Bonner, S Choudhury, W Sharp, J Sarlls, P Shaw

NHGRI
GEN-38
NIA
GEN-39

Noncoding mutations of HGF cause human deafness DFNB39: Confirmation by mouse model
Author(s): EJ Thomason, JM Schultz, EA Wilson, T Fitzgerald, M Starost, TB Friedman, RJ Morell

NIDCD
GEN-40

X-linked acro-gigantism (X-LAG): a new form of infant-onset pituitary gigantism
Author(s): G Trivellin, AF Daly, FR Faucz, B Yuan, L Rostomyan, DO Larco, MH Schernthaner-Reiter, LF Leal, C Villa, A Dimopoulos, P Chittiboina, TJ Wu, CS Choong, M Quezado, I Bjelobaba, SS Stojilkovic, S Costanzi, JR Lupski, A Beckers, CA Stratakis

NICHD
GEN-41
NIAAA
GEN-42
NIDDK
GEN-43

Mammary genetic islands: permission denied to cross the border
Author(s): KH Yoo, CM Yang, S Oh, L Hennighausen

NIDDK
GEN-44

Cell-specific significance of a common cytokine responsive enhancer
Author(s): X Zeng, HY Shin, C Wang, L Hennighausen

NIDDK
GEN-45
NIDDK
GEN-46

CGG-repeat instability in Fragile X syndrome patient-derived stem cells
Author(s): Yifan Zhou, Daman Kumari, Bruce Hayward, Karen Usdin

NIDDK
GEN-47
NIDDK
STRUCTBIO-1
CIT
STRUCTBIO-2

Glutamate Dehydrogenase: Structure and Mechanism of Regulation
Author(s): MJ Borgnia, S Banerjee, A Bartesaghi, A Merk, D Matthies, P Rao, J Pierson, JLS Milne, S Subramaniam

NCI
STRUCTBIO-3
NIAID
STRUCTBIO-4
NIAAA
STRUCTBIO-5

Allosteric Activation of Bacterial Swi2/Snf2 Protein RapA by RNA Polymerase: Biochemical and Structural Studies
Author(s): S Kakar, X Fang, L Lubkowska, YN Zhou, G Shaw, YX Wang, D Jin, M Kashlev, X Ji

NCI
STRUCTBIO-6
NCI
STRUCTBIO-7
NCI
STRUCTBIO-8

High resolution single-particle cryo-EM of a 200 kDa membrane ion channel
Author(s): D Matthies, O Dalmas, MJ Borgnia, A Merk, P Dominik, P Rao, B Reddy, S Islam, A Bartesaghi, E Perozo, S Subramaniam

NCI
STRUCTBIO-9
CIT
STRUCTBIO-10
NCI
STRUCTBIO-11

Poster Session V

Friday, September 18, 2015 — 2:00 p.m. – 3:30 p.m. — FAES Terrace

Major Determinants of Nucleosome Organization
Author(s): RV Chereji, J Ocampo, T Burke, DJ Clark

NICHD
CHROM-1

Enhancer regulation by H3K4me1/2 methyltransferase MLL4
Author(s): JE Lee, C Wang, W Peng, K Ge

NIDDK
CHROM-2

Super enhancers in the human IgH locus: roles of NF-kB and CTCF
Author(s): FC Mills, H Xu, RB Bernstein, EE Max

FDA/CBER
CHROM-3

Centromeric association of polo kinase Cdc5 regulates kinetochore structure and chromosome stability
Author(s): PK Mishra, L Boeckmann, T Pachpor, WC Au, S Ciftci, LE Dittman, Z Jowhar, S Azeem, L Bursch, D D’Amours, RE Baker, E Yeh, K Bloom, MA Basrai

NCI
CHROM-4
NCI
CHROM-5

Cajal bodies shape genome conformation
Author(s): IA Sawyer, M-H Sung, D Sturgill, Q Wang, SP Shevtsov, G Pegoraro, S Baek, GH Hager, M Dundr

NCI
CHROM-6

Comorbidity of Alcohol Dependence with Anxiety or Mood Disorders: Relationship with Age of Onset
Author(s): JP Amodio, ML Schwandt, M Farokhnia, MR Lee, LA Farinelli, L Leggio

NIAAA
EPIG-1

The APOE e4 allele is associated with an earlier onset of amyloid accumulation
Author(s): Murat Bilgel, Yang An, Yun Zhou, Dean Wong, Jerry Prince, Susan Resnick

NIA
EPIG-2

SGLT2 inhibitors and the risk of ketoacidosis
Author(s): JE Blau, SE Lock, SI Taylor, KI Rother

NIDDK
EPIG-3
CC
EPIG-4

Sex-hormones and brain volumes in middle-age men
Author(s): M Elbejjani, P Schreiner, D Siscovick, S Sidney, CE Lewis, N Bryan, LJ Launer

NIA
EPIG-5

A mediation analysis to investigate the mechanism underlying smoking and HPV re-acquisition
Author(s): RC Eldridge, M Pawlita, L Wilson, PE Castle, T Waterboer, PE Gravitt, M Schiffman, N Wentzensen

NCI
EPIG-6
NLM
EPIG-7
NIMHD
EPIG-8

Impact of changes in television viewing on total mortality: A prospective cohort study
Author(s): SK Keadle, H Arem, SC Moore, JN Sampson, CE Matthews

NCI
EPIG-9
NLM
EPIG-10

Organophosphate insecticide use and cancer incidence among spouses of pesticide applicators in the Agricultural Health Study
Author(s): CC Lerro, S Koutros, G Andreotti, MC Friesen, MC Alavanja, A Blair, JA Hoppin, DP Sandler, JH Lubin, X Ma, Y Zhang, LE Beane Freeman

NCI
EPIG-11

Maternal gestational diabetes and offspring’s obesity risk during late childhood, adolescent and early adulthood - Does sex matter?
Author(s): S Li, M Gillman, Y Zhu, E Yeung, JE Chavarro, CZ Yuan, AE Field, SA Missmer, JL Mills, FB Hu, C Zhang

NICHD
EPIG-12

Effect of bivalent human papillomavirus (HPV) vaccination on pregnancy outcomes: long-term observational follow-up in the Costa Rica HPV Vaccine Trial
Author(s): OA Panagiotou, B Befano, P Gonzalez, AR Rodríguez, R Herrero, JT Schiller, AR Kreimer, M Schiffman, A Hildesheim, AJ Wilcox, S Wacholder, Costa Rica HPV Vaccine Trial

NCI
EPIG-13
NCI
EPIG-14

Rate of carotid disease progression in asymptomatic low to moderate risk individuals: the RIGHT study
Author(s): V Sandfort, M Ahlman, S Lai, M Mallek, C Sibley, D Bluemke

CC
EPIG-15
NIA
EPIG-16
NIA
EPIG-17
NCI
EPIG-18
NCI
EPIG-19

Attention deficit hyperactivity disorder symptoms and alcohol use disorder
Author(s): SA Aston, MO Bukhari, C Frable, ML Schwandt, MR Lee, LA Farinelli, L Leggio

NIAAA
NEURO-1

Physiological Monitoring of Mice Undergoing Prolonged fMRI Scanning
Author(s): LC Bauer, LA Low, B Klaunberg, D Despres, V Diaz, B Wang, J Munasinghe, MC Bushnell

NCCIH
NEURO-2

A1 and A3 Adenosine receptors mediate hypothermia via distinct mechanisms
Author(s): JL Carlin, DK Tosh, A Panyutin, R Pinol, KA Jacobson, O Gavrilova, ML Reitman

NIDDK
NEURO-3
NIAAA
NEURO-4
NINDS
NEURO-5

Bioavailability of alcohol following oral ingestion in humans
Author(s): AM Durrani, S O'Connor, MH Plawecki, VA Ramchandani

NIAAA
NEURO-6
NINDS
NEURO-7

Threat appraisal during extinction recall in pediatric and adult anxiety disorders: an fMRI replication study
Author(s): MJ Farber, AL Gold, JC Britton, E Ronkin, E Leibenluft, DS Pine

NIMH
NEURO-8

Modulation of task-related MEG activity by SCN2A sodium channel genotype
Author(s): AH Gerlich, FW Carver, T Holroyd, D Dickinson, KF Berman, R Coppola

NIMH
NEURO-9
NICHD
NEURO-10

The DRD1-by-Urbanicity and DRD2-by-Urbanicity effect on working memory investigated by BOLD fMRI
Author(s): M Grunnagle, JL Ihne, S Marenco, DR Weinberger, KF Berman, JH Callicott

NIMH
NEURO-11

Antibiotic Treatment Exacerbates Focal Retinal Degeneration in a Mouse Model of AMD
Author(s): L Guedez, N Popp, M Abu-Asab, H Qian, Y Li, CC Chan

NEI
NEURO-12

Amygdala endocannabinoids are essential for the extinction facilitating actions of chronic fluoxetine
Author(s): O Gunduz-Cinar, S Flynn, K Kaugars, R Cinar, TS Ramikie, S Patel, G Kunos, A Holmes

NIAAA
NEURO-13

CSF-directed AAV9 gene therapy plus subcutaneous copper provides superior rescue in a mouse model of Menkes disease
Author(s): MR Haddad, D Martinelli, EY Choi, PM Zerfas, P Sullivan, DS Goldstein, D Abebe, JA Centeno, SG Kaler

NICHD
NEURO-14
NINDS
NEURO-15
NIAAA
NEURO-16

Dopamine Synthesis and Receptor Profile Vary as a Function of Body Mass Index in Humans
Author(s): AM Ianni, DP Eisenberg, CE Hegarty, JC Masdeu, MD Gregory, PD Kohn, KF Berman

NIMH
NEURO-17

Brain activation correlates of negative attentional bias in depression
Author(s): JL Ihne, AC Nugent, ML Furey, J Szczepanik, CA Zarate Jr

NIMH
NEURO-18
NIMH
NEURO-19

Efficacy of Minocycline in Female Rats after Mild Diffuse Traumatic Brain Injury
Author(s): NR Jikaria, LC Turtzo, J Lescher, W Tu, JA Frank

CC
NEURO-20

Norm-based coding of faces in the anterior fundus face patch
Author(s): AP Jones, DB McMahon, BE Russ, DA Leopold

NIMH
NEURO-21
NINDS
NEURO-22
NIAAA
NEURO-23
NIAAA
NEURO-24
NIDDK
NEURO-25
NIMH
NEURO-26

Encoding 10,000 pictures
Author(s): DA Leopold

NEI
NEURO-27
NIMH
NEURO-28

Identification of TRPML1 agonists for the treatment of lysosomal-storage disorders
Author(s): NJ Martinez, RR Calvo, NT Southall, H Xu, X Zhang, Q Gao, L Yu, J Marugan, M Ferrer

NCATS
NEURO-29
NICHD
NEURO-30
NIDDK
NEURO-31
NIAAA
NEURO-32
NINDS
NEURO-33
NIMH
NEURO-34

The role of calf strength on balance in Kennedy’s Disease
Author(s): J Rekant, J Shrader, J Woolstenhulme, G Joe, A Kokkinis, D Bakar, C Grunseich, C Zampieri

CC
NEURO-35

A System for automated video-based assessment of activity and behavior for mice housed in a home-hage environment
Author(s): G Salem, J Krynitsky, B Kirkland, E Lin, A Chan, S Anfinrud, T Pohida, J Dennis, G Wu, A Sowers, J Mitchell, V Amaral, M Bustin, S Gelman, D Serven, M Bowen, AV Kravitz, K Brason

CIT
NEURO-36

Systems analyses of RNA-Seq transcriptomic responses in dorsal horn during carrageenan-induced inflammation
Author(s): MR Sapio, SC Goswami, JR Gross, GL Gonnella, JM Keller, HD Kominsky, AJ Mannes, MJ Iadarola

CC
NEURO-37
NINDS
NEURO-38

Neural correlates of the dot-probe task in anxious and non-anxious youth
Author(s): SL Sequeira, LK White, JC Britton, DS Pine

NIMH
NEURO-39

Slowly eroding lesions in multiple sclerosis
Author(s): VV Sethi, G Nair, A Venkataraman, BE Dewey, C Shea, T Wu, K Yang, JE Ohayon, ICM Cortese, DS Reich

NINDS
NEURO-40
NICHD
NEURO-41

Comparison of EEG and fNIRS for measurement of cortical activity during motor tasks
Author(s): AK Sharma, TC Bulea, M Karker, T Sukal-Moulton, AC de Campos, DL Damiano

CC
NEURO-42
NIA
NEURO-43

Structural differences in pediatric anxiety disorders
Author(s): ER Steuber, AL Gold, J Pacheco, E Leibenluft, DS Pine

NIMH
NEURO-44
NEI
NEURO-45
NINDS
NEURO-46

The face inversion effect in rhesus macaques
Author(s): O Tomeo, N Liu, SW Li, LG Ungerleider

NIMH
NEURO-47

Neural correlates of Irritability: A novel cross-diagnosis dimensional approach
Author(s): W-L Tseng, CM Deveney, E Moroney, L Machlin, KE Towbin, DS Pine, MA Brotman, E Leibenluft

NIMH
NEURO-48

Childhood Urbanicity and BDNF Val/Met Interaction alters activation in bilateral parahippocampal gyrus
Author(s): TG Vargas Lopez, J Ihne, K Berman, D Weinberger, A Mattay, S Marenco, JH Callicott

NIMH
NEURO-49
NINDS
NEURO-50
NINDS
NEURO-51
NIDDK
NEURO-52

Schizophrenia Susceptibility Gene Dysbindin Maintains Prefrontal Function
Author(s): W Zhang, K Daly, B Liang, L Zhang, Y Li, D Lin

NIDA
NEURO-53
NIAAA
NEURO-54

Orphan GPR110 targeted by N-docosahexaenoylethanolamine: an omega-3 fatty acid-dependent mechanism for brain development
Author(s): JW Lee, G Kharebava, BX Huang, MA Rashid, S Patnaik, J Marugan, HY Kim

NIAAA
NEURO-55

A Biosensor Based, High-throughput Capable Cell Line for GPCR Ligand Analysis
Author(s): R Alvarez, C Westover, A Yazdin, J Russ, L Eiden, A Emery, W Xu, M Eiden

NIMH
PHARM-1

Peripherally restricted, Dual Target cannabinoid CB1R/ inducible NO synthase (iNOS) inhibitors with improved safety and anti-fibrotic Efficacy in liver fibrosis
Author(s): R Cinar, MR Iyer, Z Liu, T Jourdan, X Cao, K Erdelyi, G Godlewski, G Szanda, J Liu, JS Liow, P Pacher, R Innis, G Kunos

NIAAA
PHARM-2

Molecular Ber-EP4 imaging towards theranostics for basal cell carcinoma
Author(s): B Dasgeb, VM Diaz, TJ Rosales, DL Sackett, JR Knutson, AH Gandjbakhche, IF Brownell

NINDS
PHARM-3
NIDA
PHARM-4
NIMH
PHARM-5

Cannabidiol is a novel treatment for autoimmune myocarditis
Author(s): K Erdelyi, WS Lee, Cs Matyas, Z Varga, P Mukhopadhyay, P Pacher

NIAAA
PHARM-6
NIAAA
PHARM-7

Cannabinoid receptor 2 is a promising target in diabetic cardiomyopathy
Author(s): ZV Varga, M Rajesh, S Batkai, B Horvath, P Mukhopadhyay, P Pacher

NIAAA
PHARM-8

A novel cannabinoid 2 (CB2) receptor agonists, LEI-102 protects against alcohol-induced liver injury
Author(s): Y Wang, K Erdelyi, E Holovac, G Szanda, R Cinar, B Gao, G Kunos, MVD Stelt, P Pacher

NIAAA
PHARM-9

Examining the Structural Requirements for Beta Receptor Isoform Selectivity of cAMP-dependent Signaling Through NCS/Rapgef2
Author(s): CD Westover, KB Kluska, AC Emery, JC Santiago, W Xu, MV Eiden, LE Eiden

NIMH
PHARM-10

Discovery and characterization of a biologically active noncompetitive p38 MAP kinase inhibitor
Author(s): BAP Wilson, MS Alam, T Guszczynski, JD Ashwell, BR O'Keefe

NCI
PHARM-11

Constitutive mTOR inhibition in mouse thymic Pre-T LBL identifies Cdk6 as a target for combination treatment of T-ALL/LBL
Author(s): S Zhang, J Gary, J Simmons, J Xu, B Gamache, K Zhang, N Watson, A Kovalchuk, A Michalowski, J Chen, M Herrmann, T Thaiwong, M Kiupel, W Dubois, J Testa, B Mock

NCI
PHARM-12

Characterization of Envs on individual HIV particles by flow virometry
Author(s): A Arakelyan, W Fitzgerald, D King, J-C Grivel, RJ Shattock, L Margolis

NICHD
VIROL-1
NIAID
VIROL-2

Architecture of influenza hemagglutinin induced hemifusion revealed by cryo-electron tomography
Author(s): P Chlanda, E Mekhedov, H Waters, C Schwartz, RJ Ryham, FS Cohen, PS Blank, J Zimmerberg

NICHD
VIROL-3
NCI
VIROL-4
FDA/CBER
VIROL-5
NICHD
VIROL-6
VRC
VIROL-7

LEDGF promotes mRNA splicing and targets HIV-1 integration to highly spliced genes
Author(s): PK Singh, MR Plumb, AL Ferris, X Wu, HJ Fadel, JR Iben, EM Poeschla, SH Hughes, M Kvaratskhelia, HL Levin

NICHD
VIROL-8
NIAID
VIROL-9

Development of an ELISA based assay for the quantitation of haemagglutinin in influenza vaccines: An alternative to the traditional SRID
Author(s): S Verma, F Schmeisser, A Vasudevan, J Soto, W Wang, E Alvarado, C Weiss, C Meseda, J Weir

FDA/CBER
VIROL-10