Skip to main content
 

Physiological Monitoring of Mice Undergoing Prolonged fMRI Scanning

Friday, September 18, 2015 — Poster Session V

2:00 p.m. – 3:30 p.m.
FAES Terrace
NCCIH
NEURO-2

Authors

  • LC Bauer
  • LA Low
  • B Klaunberg
  • D Despres
  • V Diaz
  • B Wang
  • J Munasinghe
  • MC Bushnell

Abstract

Anesthetized mice can be used in neuroimaging studies to explore neural pathways. Anesthesia can affect cerebral blood flow and oxygenation, which are important variables for functional brain imaging. Hence, it is necessary to know about the baseline physiology of mice under anesthesia. This study explores how isoflurane anesthesia affects mouse physiological measures (arterial blood pH, respiration, heart rate) over long durations of time during which functional brain scans occur.

Category: Neuroscience