NIH Research Festival
–
Physiological Monitoring of Mice Undergoing Prolonged fMRI Scanning
– Poster Session V
2:00 – 3:30 p.m.
FAES Terrace
NCCIH
NEURO-2
Authors
- LC Bauer
- LA Low
- B Klaunberg
- D Despres
- V Diaz
- B Wang
- J Munasinghe
- MC Bushnell
Abstract
Anesthetized mice can be used in neuroimaging studies to explore neural pathways. Anesthesia can affect cerebral blood flow and oxygenation, which are important variables for functional brain imaging. Hence, it is necessary to know about the baseline physiology of mice under anesthesia. This study explores how isoflurane anesthesia affects mouse physiological measures (arterial blood pH, respiration, heart rate) over long durations of time during which functional brain scans occur.
Scientific Focus Area: Neuroscience
This page was last updated on Friday, March 26, 2021