Poster Sessions
Poster Session I
Wednesday, September 14, 2016 — 3:00 p.m. – 4:30 p.m. — FAES Terrace
Cysteamine inhibits tumor invasion in vitro and metastasis in vivo in mouse models of human ovarian cancer
Author(s): A Suzuki, P Leland, BH Joshi, RK Puri
Interleukin-13 initiates signal transduction through IL-13Rα2 in human glioma cell lines via AP-1 pathway
Author(s): R Bhardwaj, A Suzuki, P Leland, BH Joshi, RK Puri
A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2
Author(s): S Yang, P He, J Wang, A Schetter, W Tang, N Funamizu, K Yanaga, T Uwagawa, A Satoskar, J Gaedcke, M Bernhardt, BM Ghadimi, MM Matthias, F Bergmann, J Werner, T Ried, N Hanna, HR Alexxander, SP Hussain
CEBPD facilitates adaptation of human breast cancer cells to endoplasmic reticulum stress
Author(s): N Sheshadri, E Sterneck
Development of thiazole-valine peptidomimetic as modulators of human multidrug transporter P-glycoprotein
Author(s): B Abel, B Patel, T Talele*, SV Ambudkar*
Diffusion-weighted MR imaging after Near Infrared Photoimmunotherapy in an animal model
Author(s): Y Nakamura, M Bernardo, T Nagaya, K Sato, T Harada, S Okuyama, PL Choyke, H Kobayashi
Discovery of Osteosarcoma Genomic Structural Variations with NanoChannel Array technology (Irys System)
Author(s): Y Jiang, S Bilke, S Oeser, A Canela, RW Walker, J Lueders, PS Meltzer
DNA methylation characterization of fusion-positive and fusion-negative rhabdomyosarcoma primary tumors
Author(s): W Sun, B Chatterjee, JF Shern, S Sindiri, Y Wang, HS Stevenson, DC Edelman, PS Meltzer, J Khan, FG Barr
Fungal Infection and Immune Dysfunction Contribute to Esophageal Carcinogenesis
Author(s): F Zhu, J Willette-Brown, NY Song, D Lomada, Y Song, L Xue, Z Gray, SR Davis, ZH Sun, PL Zhang, XL Wu, QM Zhan, ER Richie, YL Hu
Gene-engineered human T cells targeting intrinsic checkpoint inhibitor CISH enhances anti-tumor immune response
Author(s): JH Kim, DC Palmer, N Restifo
Identification of Serum Inflammatory Markers as Classifiers of Lung Cancer Mortality for Stage I Adenocarcinoma
Author(s): CL Meaney, A Zingone, D Brown, Y Yu, L Cao, BM Ryan
Metadherin, a novel oncogenic gene in malignant pleural mesothelioma
Author(s): L Zhang, CD Hoang
Modulation of tumor PD-L1 expression by epithelial-mesenchymal phenotypic plasticity
Author(s): JM David, C Dominguez, C Palena
Nano-Proteomic Analysis Technologies: Advancing Quantitative Proteomic Research, Biomarker Assessment, and Molecular Profiling
Author(s): JQ Chen, X Luo
PAX3-FOXO1 is essential for tumor initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma
Author(s): PR Pandey, B Chatterjee, J Khan, MM Miettinen, SM Hewitt, FG Barr
Regulation of chemoresistance by a novel p53-regulated long noncoding RNA
Author(s): XL Li, M Jones, M Subramanian, Y Zhu, S Sindiri, B Gryder, H Chou, M Min, M Dasso, Y Yang, LM Wakefield, P Perez-Pinera, B Moriarity, KV Prasanth, A Lal
Restoration of p53 Function in Malignant Pleural Mesothelioma by microRNA
Author(s): A Singh, N Bhattacharyya, A Srivastava, L Zhang, CD Hoang
Histone modifications affect differential regulation of TGF-beta/SMAD3-induced Nox4 by p53
Author(s): HE Boudreau, A Korzeniowska, TL Leto
Mapping sentinel lymph node metastasis by optical imaging
Author(s): G Niu, X Yang, Z Wang, G Zhu, X Chen
Quantification of Tumor Vascular Permeability and Blood Volume by Positron Emission Tomography
Author(s): G Niu, H Chen, X Tong, L Lang, O Jacobson, X Yang, R Bai, DO Kiesewetter, Y Ma, G Niu, X Chen
Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling
Author(s): AN Stratman, OM Farrelly, MF Miller, VN Pham, D Castranova, AE Davis, Z Wang, CM Mikelis, JS Gutkind, BM Weinstein
The alternative NF-kB2/RELB pathway is activated by LTβ/LTβR and NIK to promote cell migration and metastasis related gene expression in HNSCC
Author(s): Rita Das, Tsu-F Cheng, Jamie Coupar, Antho Anthony Saleh, Paul Clavijo, Xinpi Xinping Yang, Zhong Chen, Carte Carter VanWaes
Identification of novel parafibromin protein partners using a proteomic approach
Author(s): PR Adikaram, J Zhang, M Pandey, WF Simonds
Regulation of pancreatic islet β-cell proliferation
Author(s): SS Kharade, SK Agarwal
Quantitation of cisplatin, as well as other metals, at the level of a single cell
Author(s): L Amable
Disseminated breast cancer cells require autophagy to enter cellular dormancy and survive long periods of growth-arrested state
Author(s): L Vera-Ramirez, WK Hunter, JE Green
Deep Phenotyping of Patients with Trichothiodystrophy or Xeroderma Pigmentosum
Author(s): SG Khan, J Pugh, R Bembry, ER Heller, D Tamura, M Scheibye-Knudsen, G Nelson, JJ DiGiovanna, KH Kraemer
Multiregion analysis demonstrates multiple clinically significant subclonal alterations within index foci of localized prostate cancer
Author(s): DJ VanderWeele, R Finney, K Katayama, M Gillard, G Paner, S Imoto, R Yamaguchi, D Wheeler, M Cam, K Maejima, A Sasaki-Oku, K Nakano, H Tanaka, A Pontier, D Grigoryev, M Kubo, M Ratain, S Miyano, H Nakagawa
NCI Office of Cancer Genomics: Leveraging genomics for precision oncology
Author(s): NL Jaber, JM Guidry Auvil, M Ferguson, N Griner, S Jagu, JN Mazerik, DS Gerhard
A taxonomy of medical uncertainties in clinical genome sequencing
Author(s): KL Umstead, PK Han, LG Biesecker, BA Bernhardt, RC Green, S Joffe, B Koenig, I Krantz, BB Biesecker
False positive rate inflation and admixed populations in the quantitative transmission disequilibrium test
Author(s): AM Musolf, JE Bailey-Wilson
Phenotypic and Transcriptional Differences Resulting from Two Different SPTAN1 Mutations
Author(s): PR Lee, V Gartner, T Markello, A Thurm, L Joseph, M Maeda, G Golas, A Beggs, J Schmahmann, G Berry, CJ Tifft, WA Gahl
Single-molecule sequencing and assembly of human rDNA gene clusters
Author(s): A Dilthey, S Koren, J-H Kim, R Nagaraja, D Schlessinger, V Larinov, A Phillippy
Strategic interrogation of the exome for metabolic and glycomic variants in the setting of undiagnosed disease
Author(s): CJ Adams, DR Johnson, TS Frisby, KR Chao, M Davids, LA Wolfe, H Ho, CL Hoppel, WA Gahl, DR Adams
Sudden Infant Death “Syndrome”-Insights and Future Directions from a Utah Population Database Analysis
Author(s): DR Johnson, ED Christensen, J Berger, M Alashari, H Coon, C Robinson, H Ho, DR Adams, W Gahl, K Smith, JM Opitz
The contribution of epigenetics to the phenotypic variation in a set of monozygotic twins with Gaucher disease
Author(s): Shahz Hassan, Frank Donovan, Setta Chandrasekharappa, Marie Biegstraaten, Ellen Sidransky, Nahid Tayebi
The epigenetic regulatory architecture of type 2 diabetes: progressing from associations to mechanisms
Author(s): JP Didion, DL Taylor, MR Erdos, PS Chines, M Boehnke, FS Collins
Understanding the role of RUNX1-TLE1 interaction in the pathogenesis of familial platelet disorder with associated myeloid malignancy
Author(s): HI Alkadi, Y Gao, TS Karpova, L Garret, S Wincovitch, A Sorrell, DA Ball, JJ Greene, L Cheng, PP Liu
Unraveling the skin virome of DOCK8-deficient patients
Author(s): O Tirosh, S Conlan, C Deming, NISC Comparative Sequencing Program, C Ng, S Lee-Lin, JA Segre, HH Kong
Whole transcriptome analysis of a mouse model for type 2 Gaucher disease identifies potential genetic modifiers
Author(s): R Grey, NS Trivedi, A Gonzalez, B Berhe, AG Elkahloun, E Sidransky, N Tayebi
Using Whole-Exome Sequencing to Identify Genetic Variants in Patients Diagnosed with Pentalogy of Cantrell
Author(s): B MacTaggart, C Bowen, M Markowitz, J Chong, M Bamshad, X Ma, RS Adelstein
Dissecting genetics allowing dissemination of Coccidioides spp. infections
Author(s): AP Hsu, JN Galgiani, SM Holland
The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacing in vivo
Author(s): J Ocampo, RV Chereji, PR Eriksson, DJ Clark
ChIP-Seq analysis on FACS-enriched nuclei – an alternative approach for detecting genome-wide meiotic recombination hotspots
Author(s): KG Lam, F Pratto, K Brick, RD Camerini-Otero
Comprehensive recombination maps of dog genomes
Author(s): Q Yu, F Smagulova, G Margolin, KM Brick, P Khil, F Pratto, RD Camerini-Otero, GV Petukhova
Development of a Proxy Motor Outcome Measurement Scale in Young Children with Neuromuscular Disorders
Author(s): MO Shelton, IC Arveson, F Tounkara, R Tounkara, KG Meilleur
Urban/rural disparities in breast cancer screening and incidence rates: Socioeconomic and healthcare explanations
Author(s): JL Moss, B Liu
Physiologic Dysregulation Experienced by Immigrants is Mitigated by Immigrating at a Younger Age and Family Reunification: The Africans in America Study
Author(s): BA Bingham, MT Duong, PC Aldana, M Ricks, LS Mabundo, M Udahogora, D Berrigan, AE Sumner
Vitamin D is not Related to Insulin Resistance in African-American and African Immigrant Women
Author(s): BA Bingham, PC Aldana, MT Duong, LS Mabundo, M Ricks, JT Reynolds, AE Sumner, ST Chung
Weight Misperception is Not A Barrier to User Adoption of a Mobile Health (mHealth) Wrist-worn Physical Activity (PA) Monitor System: Observations from the Washington, D.C. Cardiovascular (CV) Health and Needs Assessment
Author(s): L Yingling, S Thomas, VM Mitchell, C Ayers, MH Peters-Lawrence, G Wallen, AT Brooks, J Adu-Brimpong, D Sampson, J Henry, A Johnson, A Graham, L Graham, KL Wiley, Jr, TM Powell-Wiley
Theranostic Application of Radiolabeled Evans Blue-RGD Peptide Conjugate
Author(s): O Jacobson, H Chen, J Zhang, G Niu, ID Weiss, DO Kiesewetter, Y Liu, Y Ma, F Li, H Wu, X Chen
Taltirelin, a thyrotropin-releasing hormone analog, alleviates fatigue in healthy mice and chemotherapy-induced fatigue mouse models
Author(s): JP Dougherty, MJ Cullen, DA Springer, MC Gershengorn
Poster Session II
Thursday, September 15, 2016 — 12:00 p.m. – 1:30 p.m. — FAES Terrace
Mechanism of SAMT analog inactivation of HIV-1 Gag polyprotein
Author(s): EL Paine, KM Rosenker, HD Tagad, MT Scerba, L Deshmukh, DE Ott, DH Appella, LM Miller Jenkins
Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals
Author(s): K Le, C Li, J Kato, J Moss, M Vaughan
Imaging adipose tissue across scales of resolution: from two-photon to super-resolution microscopy
Author(s): D Malide
Macrophage Deposition of Cholesterol into the Extracellular Matrix
Author(s): XT Jin, D Sviridov, Y Liu, B Vaisman, L Addadi, AT Remaley, HS Kruth
Role of TRIM72 ADP-ribosylation cycle in myocardial injury and membrane repair
Author(s): H Ishiwata-Endo, J Kato, A Tonouchi, YW Chung, J Sun, LA Stevens, J Zhu, AM Aponte, DA Springer, H San, K Takeda, ZX Yu, V Hoffmann, E Murphy, J Moss
Muscle microtubule defects implicated in the pathology of Duchenne muscular dystrophy can be induced or normalized in adult mouse muscles by changing the level of tubb6, a minor beta-tubulin isotype
Author(s): D Randazzo, DM Talsness, JJ Belanto, KJ Zaal, MD Tran, A Kenea, DL Sackett, JM Ervasti, E Ralston
Unraveling lysosomal acidification defect in a lysosomal storage disorder model
Author(s): MB Bagh, S Peng, G Chandra, Z Zhang, SP Singh, N Pattabiraman, A Liu, AB Mukherjee
Increased de novo sphingolipid biosynthesis causes a dramatic increase in CD11b+, CD11c+ population in a novel mouse model
Author(s): S Majumder, G Tuymetova, C Giannouli, TM Dunn, RL Proia
Epithelial Cell Junction Regulation by the Stress-Associated miR-150, miR-335, and miR-142-3p in the Absence or Presence of Chronic Dexamethasone
Author(s): SK Abey, J Robinson, NH Fourie, NK Kenea, D Wang, T Vishnyakova, W Henderson
Defining the epigenetic requirements for transcription at specific genomic elements using CRISPR-Cas9
Author(s): JH Shrimp, JL Meier, C Grose
Defining the epigenetic signaling pathways regulated by cancer metabolism
Author(s): DC Montgomery, JM Garlick, RA Kulkarni, H Wu, M Vedadi, JL Meier
Fluorogenic profilinging of the oncometabolite fumarate
Author(s): TT Zengeya, JM Garlick, M Miley, RA Kulkarni, AM Roberts, DR Crooks, WM Linehan, JL Meier
HIV-1 integrase strand transfer inhibitors that reduce susceptibility to drug resistant mutant integrases
Author(s): XZ Zhao, H Peters, SJ Smith, DP Maskell, M Metifiot, VE Pye, K Fesen, C Marchand, Y Pommier, P Cherepanov, SH Hughes, TB Burke, Jr
Using the parallelogram approach to estimate human percutaneous bioavailability for novel & legacy brominated flame retardants
Author(s): GA Knudsen, MF Hughes, JM Sanders, SM Hall, LS Birnbaum
Gold Nanoparticle Coated Carbon Nanotube Ring with Enhanced Photothermal Conversion Property for Raman and Photoacoustic Imaging
Author(s): F Wang, XY Yang, B Ning, MG Harp, SH Culp, S Hu, P Huang, L Nie, JY Chen, XY Chen
Development of 2-mercaptobenzamides as small molecule inhibitors of HIV maturation
Author(s): M Saha, MT Scerba, DH Appella
Multi-walled Carbon Nanotube Functionalization with High Molecular Weight Hyaluronan Significantly Reduces Pulmonary Injury
Author(s): S Hussain, Z Ji, AJ Taylor, LM Degraff, M George, CJ Tucker, CH Chang, R Li, JC Bonner, S Garantziotis
Interplay Between Architectural Proteins In Stem Cell Chromatin Epigenetically Regulates Neural Developmet
Author(s): T Deng, Y Postnikov, S Zhang, M Bustin
The application of integration profiles to identify novel genes that contribute to heterochromatin in fission yeast
Author(s): SY Lee, Steve Hung, Kory Johnson, Henry Levin
Brd4 controls cell identity gene induction during differentiation
Author(s): J Lee, W Peng, K Ge
MLL3/MLL4 and CBP/p300 sequentially shape dynamic enhancer landscapes in brown adipogenesis
Author(s): B Lai, JE Lee, L Wang, W Peng, K Ge
Characterization of lymphatic development in the Central Nervous System
Author(s): RM Izen, U Yutaka, Y Mukoyama
Tissue-localized myeloid progenitors differentiate into pericytes through TGF-β signaling in the developing vasculature
Author(s): T Yamazaki, A Nalbandian, Y Uchida, W Li, TD Arnold, Y Kubota, M Ema, Y Mukouyama
A component of the subcortical maternal complex is required for the block to polyspermy
Author(s): EJ Vogt, K Tokuhiro, J Dean
Fascinating Femurs!! A 6-micron look into mouse bone structure
Author(s): DR Donahue, HD Morris, VM Diaz, BA Klaunberg
A cohort study of adolescent and mid-life diet and pancreatic cancer risk in the NIH-AARP Diet and Health Study
Author(s): VL Gordon-Dseagu, FE Thompson, AF Subar, EH Ruder, AC Thiébaut, N Potischman, R Stolzenberg-Solomon
Association between Body Mass Index and Waist-Hip Ratio and Prostate Cancer among European American and African American Men: the NCI-MD case-control study
Author(s): MS Pichardo, CJ Smith, W Tang, T Dorsey, D Mann, S Ambs
Associations between obesity and biliary tract cancers vary by tumor site, sex, age, and race in the Biliary Tract Cancers Pooling Project
Author(s): AL Van Dyke, B Zhu, PT Campbell, KA McGlynn, J Koshiol
Dietary adequacy among tobacco user households in Bangladesh
Author(s): MK Virk-Baker, M Parascandola
Helicobacter pylori dominates the stomach microbiota of gastric cancer patients
Author(s): J Torres, N Hu, R Medrano-Guzman, R Herrera-Goepfert, M Humphrys, L Wang, C Wang, T Ding, J Ravel, PR Taylor, CC Abnet, AM Goldstein
Optimizing Methods for Neighborhood Built Environment Virtual Audits: Data from the Washington D.C. Cardiovascular Health and Needs Assessment
Author(s): J Adu-Brimpong, N Coffey, D Berrigan, C Ayers, L Yingling, S Thomas, V Mitchell, T Powell-Wiley
Peripheral vascular functional impairment as determined by Reactive hyperemia index associates with central functional impairment as determined by Aortic Distensibility beyond traditional cardiovascular risk factors
Author(s): AK Dey, SR Sakhardande, A Chaturvedi, JB Lerman, TM Aberra, AA Joshi, P Shukla, MT Kabbany, JI Silverman, HL Teague, Q Ng, TZ Aridi, MP Playford, NN Mehta
Small dense low-density lipoprotein particle number (sLDL-p) predicts vascular inflammation independent of traditional lipid cardiovascular risk factors in psoriasis
Author(s): A Chaturvedi, B Natarajan, AK Dey, JB Lerman, TM Aberra, MP Playford, MT Kabbany, Q Ng, HL Teague, JA Rodante, AA Joshi, NN Mehta
Amyloid burden, a hallmark of Alzheimer’s disease, links to mobility decline in normal aging
Author(s): Q Tian, SM Resnick, M Bilgel, DF Wong, L Ferrucci, SA Studenski
Factors influencing red cell distribution width in community dwelling adults
Author(s): SM Tajuddin, MA Nalls, AB Zonderman, MK Evans
Leveraging seasonality of 25-hydroxyvitamin D to control for unmeasured confounders in vitamin D epidemiology
Author(s): MD Shardell, L Ferrucci
Severity of alcohol dependence is associated with the fatty acid amide hydrolase C385A missense variant
Author(s): ME Sloan, JL Gowin, J Yan, ML Schwandt, H Sun, CA Hodgkinson, D Goldman, VA Ramchandani
A longitudinal study of body iron status during pregnancy and risk of gestational diabetes: findings from a prospective, multiracial cohort
Author(s): S Rawal, SN Hinkle, W Bao, Y Zhu, J Grewal, PS Albert, NL Weir, MY Tsai, C Zhang
The growth and evolution of clinical terminologies: Comparison of SNOMED, LOINC and RxNorm: Have they come of age?
Author(s): V Huser
Constrained minimum intensity projection for improved visualization of susceptibility weighted images
Author(s): MA Castro, DL Pham, JA Butman
Multimedia-Enhanced Radiology Reports Improve Target Lesion Selection and Measurement Concordance, and Are More Efficient in Genitourinary Cancer Trials
Author(s): LB Machado, SM Steinberg, AB Apolo, LR Folio
Comparison of effective and membrane permeability of drugs in development of in silico model
Author(s): KR Yu, P Shah, X Xu
In silico Model Development for Predicting Human CYP3A4 Metabolic Stability Using Different Descriptor Generating Software and Machine Learning Techniques
Author(s): P Shah, D-T Nguyen, A Zakharov, N Katori, A Jadhav, X Xu
NCI Policy and Compliance Program in Support of Research: Risk Management, PRA/OMB Clearance, and Records Management
Author(s): L Larson, K Bailey, L Boldon
How to Access Resources at the Center for Human Immunology
Author(s): CHI Consortium
NHLBI Proteomics Core – From proteins to systems biology
Author(s): A Aponte, Y Chen, S Patel, G Wang, Y Yang, M Gucek
A Picture is Worth a Thousand Words: Development of an Informed Consent Graphic Aid Glossary
Author(s): DG Chaitt, JF Pierson, SL Kopka, JP Meyer, TJ Miller
Abstract: Delegation of Responsibilities- Guidance in Response to FDA Audits
Author(s): JN Beeler, LB Hoopengardner, K Patterson, SM Simpson, S Vogel, J Pierson, B Baseler
Adopting a CDISC data model to build a clinical data warehouse
Author(s): J Singh, KO Newell, MJ Duvenhage, PT Gumne, HK Kandaswamy, GD Marlow, CJ Whalen, A Rosenthal, M Tartakovsky
Implementing a clinical data management randomization system aimed to satisfy research regulations
Author(s): MJ Duvenhage, Y Cai, L Goldfeder, L Dodd, J Xiao, K Newell, C Whalen, A Rosenthal, M Tartakovsky
Leptin hormone replacement therapy improves insulin resistance in patients with lipodystrophy independent of food intake
Author(s): A Valencia, R Brown
FaceMatch: a visual search system for family reunification during disasters
Author(s): E Borovikov, M Bonifant, G Lingappa, M Gill, G Thoma
PubMed ‘Early Alerts’: Towards Better Precision of Literature Searching for Pharmacovigilance Information based on an Assessment of Relevance Feedback
Author(s): AM Ripple, AF Sorbello, S Haider, O Bodenreider
Text Processing of Clinical Research Protocols and Informed Consents to Facilitate Tracking of Research Procedures
Author(s): Alok Panny, Huser Vojtech
Capacity building, collaboration, and measuring the impact of FIC’s Division of International Epidemiology & Population Studies: A bibliometric analysis
Author(s): AA Livinski, C Viboud
Careers for NIH scientists in technology transfer & business development
Author(s): SM Ferguson, JW Thomas
NIH scientists and the Federal Laboratory Consortium for Technology Transfer (FLC
Author(s): AZ Amar, SM Ferguson, GK Jones
The Bibliometric Services Program at the NIH Library
Author(s): YL Lu, CW Belter, L Charles, M Davis, A Livinski, N Terry, H Thompson
The NIH Library Bioinformatics Support Program
Author(s): M Bhagwat, B Brandys, D Joubert, K Kavanaugh, C Kelly, D McDowell, M Pham, H Phonthachack, T Sisay, H Thompson, M Walden, L Young
The NIH Working Group on Women in Biomedical Careers: Helping to Reduce Bias and Barriers for Women in Science
Author(s): WL Barfield, JL Plank-Bazinet, RO Bray, MA Bernard, JA Clayton
Stress-responsive gene expression changes in cultured human embryonic stem cells following low dose, clinical diagnostic X-ray imaging CT scan procedures
Author(s): MV Sokolov, R Maass-Moreno, RD Neumann
Translating induced pluripotent stem cells into drug discovery and regenerative medicine applications
Author(s): I Singec, Y Chen, P Ormanoglu, S Titus, C Austin, A Simeonov
Lipolysis Pathway Sustains Normal and Transformed Stem Cells in Adult Drosophila
Author(s): SR Singh, X Zeng, J Zhao, Y Liu, SX Hou
Lsh/HELLS regulates self-renewal/proliferation of neural stem/progenitor cells associated with control of Bmp4 and Cdkn1a expression
Author(s): Y Han, J Ren, E Lee, W Yu, K Muegge
Maturation of Induced Pluripotent Stem Cell Derived Cardiomyocytes via Co-Culture with Supporting Cells of the Developing Heart
Author(s): IH Garcia-Pak, W Li, E Tampakakis, Y Lin, J Zou, C Kwon, Y Mukoyama
Egg from ovarian stem cells develops into embryo
Author(s): S Park, K Marquis, EF Wolff, AH Decherney
Predictive modeling of coronary artery calcium: Integration of patient genotype, transcriptome and clinical data
Author(s): C Oguz, SK Sen, AR Davis, LG Biesecker, GH Gibbons
A major role for the transcription factor Ikaros in sustaining the inflammatory gene program in LPS-activated macrophages
Author(s): Kyu S Oh, RA Gottschalk, NW Lounsbury, Jing Sun, SJ Baek, B Dutta, GL Hager, MH Sung, GL Hager
Are pathogen-specific immune responses ‘coded’ in the language of single-cell NF-kappaB dynamics?
Author(s): EW Martin, HP Patel, FT Ardori, L Tessarollo, M-H Sung
Association of hepatic disease markers APRI and FIB-4 with ω-7 polyunsaturated fatty acids in alcohol dependent patients
Author(s): T Klepp, V Vatsalya, ML Schwandt, DT George, N Diazgranados, VA Ramchandani
ADP-ribosylation in the innate immune response
Author(s): CM Daniels, J Sun, R Gottschalk, A Nuccio, NP Manes, I Fraser, A Nita-Lazar
Proteomics and transcriptomics of the terminal ileum of conventional versus germ-free mice
Author(s): NP Manes, N Shulzhenko, A Morgun, A Nita-Lazar
Regulated hypothermia in mouse is caused by AMP, adenosine A1 and A3 receptor agonists via three distinct mechanisms
Author(s): JL Carlin, DK Tosh, S Jain, O Gavrilova, KA Jacobson, ML Reitman
Skin surface temperature gradients as a marker of cold-induced vasoconstriction
Author(s): CJ Duckworth, BP Leitner, RJ Brychta, KY Chen
Assessing the utility of gadolinium-based contrast agents administered by the intravenous and the intraperitoneal route in rodents in magnetic resonance imaging
Author(s): VM Diaz, JS Kumar, JP Munasinghe, MD Hall, MM Gottesman, BA Klaunberg
Poster Session III
Thursday, September 15, 2016 — 3:30 p.m. – 5:00 p.m. — FAES Terrace
Clinical and immunologic impact of short course enzalutamide without androgen deprivation therapy for biochemically recurrent prostate cancer
Author(s): R Amrit Madan, J Hodge, J Schlom, JL Gulley, WL Dahut
Structural Studies on the Multidrug Transporter P-glycoprotein Suggest a Mechanism for Polyspecificity
Author(s): MM Gottesman, L Esser, S Shukla, F Zhou, G Frank, S Ambudkar, S Subramaniam, D Xia
Repression of the antioxidant NRF2 pathway in premature aging
Author(s): N Kubben, T Voss, T Misteli
Can One Dose of an HPV Vaccine Confer Long-term Protection against HPV-induced Cancers?
Author(s): D.R. Lowy, B. Cortes, M. Gail, P. Gonzalez, A. Hildesheim, L. Pinto, C. Porras, J. Sampson, M. Schiffman, A.R. Kreimer
Modeling UV-induced Initiation and Progression of Human Melanoma in the Mouse
Author(s): HT Michael, C Day, A Michalowski, M Lee, G Merlino
In pursuit of authenticity: IPS cell-derived RPE for clinical applications
Author(s): K Miyagishima, Q Wan, B Corneo, R Sharma, M Lotfi, N Boles, F Hua, A Maminishkis, Congxiao, TM Blenkinsop, V Khristov, B Jha, O Memon, S D’Souza, S Temple, S Miller, K Bharti
Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality
Author(s): H-Y Shih, G Sciume, Y Mikami, L Guo, HW Sun, SR Brooks, JF Urban, Jr, FP Davis, Y Kanno, JJ O'Shea
3D ultrastructural analysis of pancreatic beta cells by serial block face scanning electron microscopy
Author(s): MA Aronova, EL McBride, A Rao, Q He, G Zhang, T Cai, H Xu, AL Notkins, RD Leapman
PRKACA defects and adrenal tumors: Animal studies and gene dosage effects
Author(s): P Salpea, A Angelousi, B Yuan, FR Faucz, I Levy, B Delemer, S Hieronimus, B Feve, F Kelestimur, G Raverot, J Bertherat, JR Lupski, M Serpe, CA Stratakis
Single-Cell RNA-Seq Analysis of the Endolymphatic Sac of the Mouse Inner Ear
Author(s): K Honda, J Burns, M Kelly, M Hoa, M Kelley, P Wangemann, R Morell, A Griffith
Determining the Factors Governing Increased Susceptibility to Periodontal Diseases
Author(s): M Somerman, Laboratory of Oral Tissues Biology, NIAMS, collaborators trans-NIH and our extramural (national and international) partners
Regulation of UNC-130/FOXD-Mediated Mesodermal Patterning in C. elegans
Author(s): RK Kersey, TM Brodigan, T Fukushige, MW Krause
Thromboxane (TXA2) Attenuates Th9 Cell Differentiation and Function During Allergic Lung Inflammation
Author(s): H Li, JA Bradbury, ML Edin, AF Gruzdev, MA Sparks, JP Graves, SL Hoopes, LM DeGraff, CD Bortner, TM Coffman, DC Zeldin
Older Age Results in Differential Gene Expression after Mild Traumatic Brain Injury and is Linked to Insufficient Neuronal Recovery Detected through MRI
Author(s): Y Cho, L Latour, H Kim, A Olivera, W Livingston, C Lai, J Gill, A Cashion
Computational Pipelines Connecting Data Wells and Fountains to Information Nuggets
Author(s): D Landsman, I Zhu, T Deng, S Zhang, M Bustin
Highly Sensitive Dual Amplicon-based NGS Approach for Bacterial Identification in Primary Clinical Specimens
Author(s): PP Khil, J-H Youn, J Ho, JP Dekker, KM Frank
Variable Effects of Severe Aplastic Anemia Treatment on the Oral Microbiome
Author(s): NJ Ames, J Barb, H Kim, A Oler, A Ranucci, R Childs, D Townsley, A Cashion, G Wallen
Molecular epidemiology, genomics and evolution of Mycobacterium tuberculosis antibiotic resistance in Belarus, 2010–2013
Author(s): K Wollenberg, C Desjardins, A Zalutskaya, V Slodovnikova, M Quiñones, A Oler, T Abeel, M Tartakovsky, A Gabrielian, S Hoffner, A Rosenthal, A Skrahin, B Birren, A Earl, A Skrahina
Novel compounds from sphagnum bog bacteria kills Mycobacterium tuberculosis
Author(s): M Espinoza-Moraga, HI Boshoff, CE Barry 3rd
Employing CRISPR/Cas for the identification of virulence-critical effectors in an intracellular pathogen
Author(s): NA Ellis, B Kim, MP Machner
Structural and Functional Alterations in the Colonic Microbiome in a Rat Model of Stress Induced Irritable Bowel Syndrome
Author(s): NH Fourie, D Wang, SK Abey, AL Creekmore, S Hong, C Martin, JW Wiley, WA Henderson
Absence of IQGAP1 impairs insulin signaling and leads to insulin resistance
Author(s): AC Hedman, B Chawla, S Sayedyahossein, HH Erdemir, Z Li, DB Sacks
IQGAP1 binds to YAP and modulates its transcriptional activity
Author(s): S Sayedyahossein, Z Li, AC Hedman, CJ Morgan, DB Sacks
Collaboration and direct interaction between Hsp90 and Hsp70 of E. coli
Author(s): AN Kravats, SM Doyle, JR Hoskins, O Genest, S Wickner
DNA-binding Triggers Tetramerization of the Glucocorticoid Receptor in Live Cells
Author(s): DM Presman, S Ganguly, RL Schiltz, TA Johnson, TS Karpova, GL Hager
Humanization of rabbit monoclonal antibodies for cancer therapy
Author(s): YF Zhang, M Ho
Mechanistic insights into anti-adaptor mediated regulation of proteolysis
Author(s): A Tripathi, A Battesti, A Kravats, J Hoskins, S Wickner, GX Shaw, J Gan, P Subburaman, YN Zhou, X Ji, S Gottesman
Untangling the role of the C-terminus of Hfq in sRNA regulation
Author(s): K Kavita, A Santiago-Frangos, DJ Schu, SA Woodson, S Gottesman
Discovering genes and pathways involved in maintenance of epithelial phenotype in retinal pigment epithelium cells
Author(s): JR Chang, BS Jha, M Lal, R Sharma, M Ferrer, K Bharti
Overexpression, purification, and characterization of a membrane-bound receptor for PEDF
Author(s): J Bullock, P Subramanian, SP Becerra
Evaluation of live-cell substrates for non-inhibitory small molecule chaperone therapy for Gaucher disease
Author(s): S Patnaik, W Westbroek, J Marugan, E Sidransky
Effects of Heterologous Expression of Human Cyclic Nucleotide Phosphodiesterase 3A (hPDE3A) on Redox Regulation in Yeast
Author(s): DK Rhee, JC Lim, SC Hockman, F Ahmad, DH Woo, YW Chung, S Liu, AL Hockman, VC Manganiello
Integrative Transcriptome Analyses of Metabolic Responses in Mice Define Pivotal LncRNA Metabolic Regulators
Author(s): L Yang, P Li, W Yang, X R, K Kiesewetter, J Zhu, H Cao
Reduced NLRP3 Inflammasome Activity in PDE3B-KO mice is associated with increased insulin sensitivity
Author(s): F Ahmad, Y Chung, Y Tang, S Hockman, S Liu, Y Khan, K Huo, E Billings, M Amar, A Remaley, V Manganiello
Regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter
Author(s): RJ Parks, S Menazza, AM Aponte, T Finkel, E Murphy
Decoding AGE-RAGE signal generated NF-kappaB RelA “barcode” that directs collagen I expression and impacts arterial aging
Author(s): Y Peng, JM Kim, HS Park, A Yang, C Islam, EG Lakatta, L Lin
Novel clinically relevant model of alcohol-induced cardiomyopathy associated with impaired cardiovascular function and cardiometabolic dysregulation
Author(s): J Paloczi, Cs Matyas, ZV Varga, K Erdelyi, P Mukhopadhyay, P Pacher
Functional analysis of H19 long non-coding RNA by CRISPR gene editing
Author(s): B Rahat, A Mitra, L Brandenberger, K Pfeiffer
Genetic deletion of a recently evolved 2.4 Mb tandem zinc finger gene cluster causes retrotransposon activation in mice
Author(s): G Wolf, M Tinkham, D Hoang, TS Macfarlan
Not merely a cofactor: eukaryotic Initiation Factor 4B (eIF4B) acts independently of eIF4A and preferentially stimulate translation of long mRNAs with structured 5’UTRs and low potential for closed-loop assembly
Author(s): ND Sen, F Zhou, M Harris, NT Ingolia, AG Hinnebusch
Significance of a Tripeptide Motif- Leu-Tyr-Arg (LYR) Fe-S Cluster Acquisition by Proteins
Author(s): A Jain, A Singh, N Maio, TA Rouault
Anti-amyloid activity of human DnaJB6 protein chaperone is selective
Author(s): DC Masison, M Reidy, C Lin, S Kumar, Dr Jyotsna
Critical role of β-arrestin-2 in regulating adipocyte function and whole body glucose and energy homeostasis
Author(s): SP Pydi, S Jain, J Liu, T Finkel, J Wess
Distinct roles of transcription factors GR, KLF4, Krox20 and PPARg in adipogenesis
Author(s): YK Park, L Wang, A Giampietro, B Lai, JE Lee, K Ge
LDB1-mediated enhancer looping independent of the RNA Pol II transcription initiation complex, Mediator and cohesin
Author(s): I Krivega, A Dean
The lncRNA MEG3 is an epigenetic determinant of oncogenic signaling in multiple endocrine neoplasia type 1
Author(s): S Iyer, SK Agarwal
Oxidized deoxynucleotides confound the ligation step in base excision repair and lead to cell death
Author(s): M caglayan, JK horton, NF stefanick, SH wilson
Role of counterions in acidification in mouse liver lysosomes
Author(s): JA Mindell, A Amin
LC-MS analysis of lactulose challenge and the microbiome
Author(s): PV Joseph, NH Fourie, EG Ferguson, SK Abey, PJ Walter, LB Sherwin, B Rahim-Williams, L Leggio, WA Henderson
PKCδ-expressing cells in the central amygdala modulate tactile hypersensitivity in a mouse model of neuropathic pain
Author(s): TD Wilson, G Soroosh, YG Carrasquillo
iPSC-derived dopaminergic neurons for exploring the pathophysiology of GBA1-associated Parkinson disease and for testing new therapies
Author(s): BT McMahon, E Aflaki, EA Sidransky
Baclofen alters subjective response to alcohol: A human laboratory study
Author(s): M Farokhnia, MR Lee, ML Schwandt, L Sewell, T Lionetti, D Spero, L Farinelli, L Leggio
Chronic alcohol exposure disrupts metabotropic glutamate receptor-mediated modulation of neurotransmission in the striatum
Author(s): KA Johnson, DM Lovinger
N-Docosahexaenoylethanolamine ameliorates LPS-induced brain inflammation through suppression of microglia cell activation as well as proinflammatory mediators expression
Author(s): TY Park, H Chen, JW Lee, Karl Kevara, HY Kim
Striatal dopamine transporter availability decreases throughout the day in healthy volunteers
Author(s): CE Wiers, E Shokri-Kojori, C Wong, D Tomasi, GJ Wang, N Volkow
Development and Mechanisms of Gnrhr Transcription in Rodent Pituitary Gonadotrophs
Author(s): MM Janjic, I Bjelobaba, J Tavcar, M Kucka, M Tomic, SS Stojilkovic
Phosphatidylinositol 4-kinase type IIIα (PI4KA) is required for proper myelination of peripheral nerves in mice
Author(s): A Alvarez-Prats, I Bjelobaba, K Yeun Ju, D Abebe, T Balla
Projections from the central nucleus of the amygdala and their role in alcohol dependence
Author(s): EG Lowery-Gionta, J Vendruscolo, H Wang, L Thomas, L Vendruscolo, M Morales, GF Koob
Differential Regulation of Energy Homeostasis by Hypothalamic Bombesin-Like Receptor-3 Populations
Author(s): RA Piñol, SH Zahler, BK Tan, C Xiao, O Gavrilova, A Kravitz, MK Krashes, ML Reitman
ABC transporter expression in drug-resistant epilepsy
Author(s): LD Weidner, P Kannan, MD Hall, RB Innis, WH Theodore, J Mulder
Anxiety enhances right dorsolateral prefrontal cortex activity during retrieval in behavioral pattern separation paradigm
Author(s): A Hsiung, N Balderston, M Ernst, C Grillon
Cortical and Subcortical Brain Structure in Pediatric Anxiety Disorders
Author(s): JF Sachs, ER Steuber, J Pacheco, LK White, E Leibenluft, DS Pine, AL Gold
EEG-based Graph Theoretical Measures as Biomarkers of Clinical Outcome in Electroconvulsive and Magnetic Seizure Therapy
Author(s): Z-D Deng, SM McClintock, SH Lisanby
Impact of anxiety on neural and behavioral responses to incentives
Author(s): B Fuchs, C Grillon, M Ernst, A Gorka
Ketamine differentially influences healthy subjects and depressed patients’ neural responses in the amygdala during emotion processing
Author(s): J Szczepanik, J Ihne, A Nugent, ML Furey, CA Zarate
Neural and physiological associations between 7.5% CO2-evoked panic and anticipatory anxiety in healthy individuals
Author(s): JY Liu, NL Balderston, M Ernst, C Grillon
TMS studies of working memory enhancement and deep brain stimulation
Author(s): B Luber, Z-D Deng, A Peterchev, S Davis, D Murphy, SH Lisanby
Cdk5 dysfunction increases the intrinsic rate of aging
Author(s): JM Spurrier, A Shukla, E Giniger
Defining functional domains of temperature- and capsaicin-activated TRPV1 channels
Author(s): KE Huffer, A Jara-Oseguera, KJ Swartz
Development of a model system for neuronal dysfunction in Fabry Disease
Author(s): CR Kaneski, RO Brady, JA Hanover, UH Schueler Hoffman
Investigating the role of fibrinogen in inflammatory demyelination using combined high-resolution MRI and histopathology in the marmoset experimental autoimmune encephalomyelitis model
Author(s): NJ Lee, SK Ha, NJ Luciano, EC Leibovitch, J Lefeuvre, MK Schindler, P Sati, K Akassoglou, AC Silva, S Jacobson, DS Reich
MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy
Author(s): N Pourshafie, P Lee, K Chen, G Harmison, L Bott, M Katsuno, G Sobue, B Burnett, K Fischbeck, C Rinaldi
Mapping Neurotransmitter Receptors to Active Synaptic Circuits by Fluorescence Complementation
Author(s): P Muthuirulan, CY Ting, CH Lee
Poster Session IV
Friday, September 16, 2016 — 12:00 p.m. – 1:30 p.m. — FAES Terrace
Associations Between Energy, Alcohol, and Macronutrient Intake and Measures of Sleep Quality
Author(s): R Gabauer, D Gitt, S Goff, E Reese, S Bernstein, K Zambell, A Courville, M Skarulis
Predictors of Work Status Change in Cancer Caregivers
Author(s): JJ Thilmany, SD Klagholz, LD Wehrlen, L Yang, LS Wiener, SL Zadeh, AC Ross, MF Bevans
Sleep disturbance is not created equal: latent class analysis in individuals who are alcohol dependent in recovery
Author(s): AT Brooks, J Park, M Krumlauf, VA Ramchandani, GR Wallen
Social adjustment in long-term survivors of allogeneic hematopoietic stem cell transplantation (aHSCT)
Author(s): J Park, L Wehrlen, L Yang, SA Mitchell, MF Bevans
Attitudes and Perceptions in an Authorized Deception Placebo Analgesia Research Study
Author(s): SJ Goo, EA Richards, BL Justement, PJ Korb, B Walitt, MC Bushnell
Research participants’ views about the process to consent to participate in a genome sequencing study
Author(s): E Turbitt, AR Heidlebaugh, PP Chrysostomou, HL Peay, LM Nelson, BB Biesecker
Neuroimaging, omega-3, and reward in adults with ADHD: Preliminary results; Blood levels of omega-3 fatty acids and symptoms of ADHD
Author(s): SE Haven, RV Gow, SF Majchrzak-Hong, JD Loewke, YH Lin, R Momenan, JR Hibbeln
Rate of consumption as a risk factor for alcohol use disorders: Evidence from a laboratory model
Author(s): JL Gowin, ME Sloan, BL Stangl, J Stoddard, V Vatsalya, VA Ramchandani
The effects of sensitivity on hangover symptoms after IV alcohol self-administration in non-dependent drinkers
Author(s): LE Blau, BL Stangl, VA Ramchandani
Differential assessment of anxiety during fear conditioning and extinction in children
Author(s): JS Feldman, DS Pine, NA Fox, KJ Michalska
Distinct psychophysiological reactivity to predictable and unpredictable threat of shock in anxiety pathologies
Author(s): G Alvarez, M Ernst, C Grillon
Radiation-related fatigue and oxidative stress
Author(s): KA Dickinson, LR Feng, C Johnson, W Du, W Lau, LN Saligan
The Relationship Between Impulsivity and Control Over Drinking on IV Alcohol Self-Administration in Non-Dependent Drinkers
Author(s): CL Vaughan, BL Stangl, ME Sloan, VA Ramchandani
Automatic lymph node cluster segmentation using holistically-nested neural networks and structured optimization in CT images (* Early accepted to Medical Image Computing and Computer Assisted Intervention Conference (MICCAI))
Author(s): I Nogues, L Lu, X Wang, H Roth, G Bertasius, N Lay, J Shi, Y Tsehay, RM Summers
Comparison of QSM estimation methods using multiple head orientations
Author(s): W-T Wang, H Ravi, D Pham, JA Butman
Learning to Read Chest X-Rays: Recurrent Neural Cascade Model for Automated Image Annotation
Author(s): H-C Shin, K Roberts, L Lu, D Demner-Fushman, J Yao, RM Summers
Can a 10 minute Bi-Parametric MRI Detect Prostate Cancer in a Relatively Low Risk Patient Population? A Multi-Reader Study
Author(s): FV Mertan, M Greer, J Shih, T Barrett, S Borofsky, YM Law, S Rais-Bahrami, M Taffel, A Westphalen, V Moreno, A George, P Pinto, B Wood, MJ Merino, P Choyke, B Turkbey
The electrochemical transmission of the proton-motive force in mitochondrial reticulum
Author(s): KD Patel, B Glancy, RS Balaban
A new temporal dimension for multisignal sedimentation velocity as a tool to analyze multicomponent interactions
Author(s): SK Chaturvedi, EA Andrade, G Patterson, H Zhao, P Schuck
AFM studies of the structure and physical properties of Microtubules
Author(s): M Raftari, C Garcia, HS Liaol, AJ Jin, D Sackett
Analytical Ultracentrifugation with Fluorescence Detection System Using Photoswitchable GFPs as Time Domain Probes
Author(s): H Zhao, Y Fu, C Glasser, E Andrade, M Mayer, G Patterson, P Schuck
Atomic force microscopy: A tool for high resolution imaging and force spectroscopy in biology
Author(s): EK Dimitriadis
BIO-AFM for evaluation of cancer treatment
Author(s): X Fu, Z Wang, A Bhirde, J Zhu, H Liao, N Carvajal, G Niu, H Eden, X Tang, X Chen, A Jin
Biomedical Engineering and Physical Science (BEPS) Shared Resource
Author(s): HS Eden, EK Dimitriadis, AM Gorbach, HR Kalish, NY Morgan, G Zhang
Microfabricated structures for biology
Author(s): NY Morgan, M Raghavan, D Sun, D Srinivasachar, S Srinvas
Sub-slice resolution in serial block face SEM of biological structures at near isotropic spatial resolution using multiple beam energies and Monte Carlo simulations
Author(s): Q He, G Zhang, RD Leapman
Cerebral Hemodynamics of the prefrontal cortex in Toddlers: A Pilot study using functional Near Infrared Spectroscopy
Author(s): E Smith, F Chowdhry, A Thurm, A Gandjbakhche
Facial plethora: modern technology for quantifying an ancient clinical sign and its use in Cushing syndrome
Author(s): A Afshari, Y Ardeshirpour, MB Lodish, E Gourgari, M Keil, F Chowdhry, E Belyavskaya, C Lyssikatos, V Chernomordik, C Stratakis, AH Gandjbakhche
Short Term Memory/ Decision Making Analysis of Brain Using functional Near Infrared Spectroscopy
Author(s): Hadis Dashtestani, Amir Gandjbakhche
Outer hair cell stereocilia bundle stiffness and mechanical coherence by horizontal top connectors determined using acoustic frequency modulation atomic force microscopy
Author(s): AX Cartagena-Rivera, E Verpy, C Petit, RS Chadwick
Differences in genetic mutations in BCG strains isolated from brain and lung tissue of a patient infected with Mycobacterium bovis, after receiving the Bacillus Calmette-Guérin vaccine
Author(s): H Tettelin, CB Korol, SJ Shallom, AF Freeman, E Sampaio, SM Holland, SD Rosenzweig, AM Zelazny
A Longitudinal Support Vector Regression for Prediction of ALS Score
Author(s): W Du, H Cheung, CA Johnson, I Goldberg, M Thambisetty, K Becker
Identifying genes to predict cancer radiotherapy-related fatigue with machine-learning methods
Author(s): CA Johnson, K Filler, W Du, WW Lau, LN Saligan
Detection of homozygous deletions in tumor suppressor genes ranging from dozens to hundreds nucleotides
Author(s): LC Chang, S Vural, D Sonkin
K-Ras4B-RASSF5 Activation Mechanism: How does K-Ras4B Regulate the Hippo pathway and YAP1 Expression through RASSF5?
Author(s): T Liao, H Jang, D Fushman, R Nussinov
Next Generation Sequencing Analysis Pipelines Offered by CCR Collaborative Bioinformatics Resource
Author(s): D Wheeler, F Elloumi, P Jailwala, B Kim, J Lack, M Cam
Canu: a new PacBio and Nanopore assembler for genomes large and small
Author(s): S Koren, BP Walenz, K Berlin, AM Phillippy
Classifying Orthogroups with Recursive Dynamic Markov Clustering
Author(s): SR Bond, AD Baxevanis
Incorporating variant analysis in microRNA coding genes and microRNA target sites into the standard exome analysis pipeline
Author(s): TS Frisby, CC Lau, CJ Adams, MJ Warburton, NI Balanda, BN Pusey, WA Gahl, DR Adams
The Missing Parent Problem: Attempting Parental reconstruction through sibling analysis
Author(s): BN Pusey, KR Chao, CC Lau, WA Gahl, DR Adams, TC Markello
Global organization of a protein binding site network gives insight into an evolutionary trace and structure-function relationships of binding sites
Author(s): J Lee, J Konc, D Janezic, BR Brooks
Nonlinear Mixed-Effects Modeling of Luminex Bead-Based Multiplex Assays: A Bioinformatics Post-Hoc Approach to Improve Signal-to-Noise Ratios
Author(s): J Candia, A Biancotto, JS Tsang
Markerless Detection and Tracking of Subcellular Structures for Fluorescent Time-Lapse Microscopy
Author(s): HP Patel, MH Sung
A conceptual framework to address challenges in applying standards to metadata collected in microbiome studies
Author(s): M Quiñones, L Kim, D Liou, I Misner, C Shyu, N Weber, D Hurt
Comparative study for classification of radiology images for Tuberculosis patients
Author(s): A Gabrielian, E Engle, O Juarez-Espinosa
Using a data warehouse model based on CDISC SDTM for centralized data and safety reporting for clinical trials
Author(s): KO Newell, J Xiao, M Duvenhage, J Singh, P Gumne, H Kandaswamy, C Whalen, A Rosenthal, M Tartakovsky
A Computational Model of Olivocochlear Neurons to Determine Effects of Synaptic Circuitry on Action Potential Generation
Author(s): JA Drew, CJ Weisz
NLM 3D Anatomy Collection: Development of a Drupal-based open-source library of medical imaging-derived 3D models
Author(s): KM Browne, A Altemus
Recent improvements to the NCBI BLAST service
Author(s): G Boratyn, C Camacho, A Fong, Y Merezhuk, T Rackers, Y Raytselis, J Ye, I Zaretskaya, P Cooper, W Matten, S McGinnis, T Tao, TL Madden
RefSeq: Curation of stop codon recoding in vertebrates
Author(s): B Rajput, TD Murphy, KD Pruitt
SimpleITK: image analysis via a simplified interface to the insight segmentation and registration toolkit
Author(s): B Lowekamp, D Chen, Z Yaniv, T Yoo
Allosteric Control of Antibody-Prion Recognition through Oxidation of a Disulfide Bond between the CH and CL Chains
Author(s): J Zhao, R Nussinov, B Ma
Approach towards immunotherapy for Neurofibromatosis type I
Author(s): S Karmakar, KM Reilly
Cytokine combinations induce human monocytic myeloid-derived suppressor cells to differentiate into M1 macrophages
Author(s): D Bayik, D Tross, DM Klinman
Epigenomic effects of Glucocorticoids on Macrophages
Author(s): K Oh, RA Gottschalk, S Baek, WS Lee, GL Hager, ID Fraser, MH Sung
Cxcr4 haploinsufficiency confers a selective advantage for hematopoietic stem cell engraftment
Author(s): E Yim, J-L Gao, PM Murphy
Long term clinical outcomes of HES subjects treated with mepolizumab (anti-IL5)
Author(s): FL Kuang, MP Fay, JA Ware, P Khoury, AD Klion
Characterization of low-density granulocytes in autoinflammatory disorders
Author(s): PD Mistry, M Purmalek, A Jones, AK Ombrello, I Aksentijevich, DL Kastner, MJ Kaplan
Epithelial DLX3-dependent transcriptome maintains normal skin immune homeostasis
Author(s): S Bhattacharya, JC Kim, G Nakato, Y Ogawa, M Udey, M Morasso
Lipoprotein subfractions and cardiovascular disease in systemic lupus erythematosus
Author(s): SR Sakhardande, MM Purmalek, M Sampson, A Joshi, Y Temesgen-Oyelakin, AM Fike, T Salahuddin, B Natarajan, J Lerman, Z Manna, A Dey, M Davis, M Chen, SA Hasni, NN Mehta, AT Remaley, MJ Kaplan
Watching single molecules at work in living B cells
Author(s): J Xu, M Dose, EM Stevens, Z Liu, H Shroff, D Mazza, D Straveva, GL Hager, R Casellas
Epigenetic modulation of interferon-stimulated gene expression by the histone chaperone HIRA and the variant histone H3.3
Author(s): M Bachu, C Chen, A Narain, A Nishiyama, I Zhu, T Tamura, H Gosh, D Landsman, K Ozato
Role of SLAMF Immunoregulatory Molecules in the MS Disease Processes
Author(s): J Park, R Masvekar, P Kosa, B Bielekova
A novel analytical method for identifying gene clusters predictive of post-radiotherapy chronic fatigue symptoms in prostate cancer patients
Author(s): SA Raheem, RL Feng, LN Saligan
Plasma extracellular vesicles in chronic stress and functional link to epithelial cell migration and wound repair
Author(s): SK Abey, Y Yuana, ND Kenea, PV Joseph, NH Fourie, LB Sherwin, GE Gonye, PA Smyser, ES Stempinski, WA Henderson
The role of TRAIL in cancer-related fatigue following radiation therapy
Author(s): LN Saligan
Fragment-Based Drug Discovery by X-ray Crystallography
Author(s): GT Lountos, WM Hewitt, K Zlotkowski, SD Dahlhauser, LB Saunders, D Needle, JE Tropea, C Zhan, G Wei, B Ma, R Nussinov, JS Schneekloth, Jr, DS Waugh
Probing GPCR conformation in cell by chemical crosslinking and mass spectrometry
Author(s): BX Huang, J-W Lee, H-Y Kim
Design and fabrication of biomolecular models using extrusion 3D printing
Author(s): J Tyrwhitt-Drake, E Da Viega Beltrame, J Suckale, D Pomeranz Krummel, I Roy, P Cruz, DE Hurt
Similarity-ordered heat maps: A new tool for analyzing molecular dynamics simulations
Author(s): P Cruz, R Squires, H Griggs, A Gabrielian, D Hurt
Ultrastructural investigation of mitochondrial networks by serial block face scanning electron microscopy
Author(s): MA Aronova, GN Calco, BC Kuo, JD Hoyne, G Zhang, RD Leapman
Functional characterization of proteins by domain architecture
Author(s): RA Yamashita, L Geer, L Han, C Lanczycki, S Lu, J He, F Chitsaz, M Derbyshire, N Gonzales, M Gwadz, F Lu, G Marchler, J Song, N Thanki, J Wang, C Zheng, S Bryant, A Marchler-Bauer
How the proteasome recognizes its ubiquitinated substrates
Author(s): X Chen, Y Shi, S Elsasser, BB Stocks, SG Tarasov, JR Engen, D Finley, KJ Walters
A novel HIV-1 inhibitor blocks ubiquitin recognition by Tsg101
Author(s): M Strickland, LS Ehrlich, S Watanabe, M Khan, M-P Strub, EJ Seo, MD Powell, J Leis, C Carter, N Tjandra
Evaluation of Zika Virus Inactivation in Whole Blood Via UV Irradiation and Photosensitizers
Author(s): Y He, F Xu, DE Scott, J Vostal, JL Reed
Small molecule inhibitors of Zika virus replication identified from a drug repurposing screen
Author(s): Miao Xu, Jenni Kouznetsova, Ruili Huang, Wenwe Huang, Misha Itkin, Paul Shinn, Samue Michael, Anton Simeonov, Mengh Xia, Wei Zheng
Characterization of pandemic 1918 H1 hemagglutinin on influenza virus-like particles for optimizing vaccine design
Author(s): DM McCraw, JR Gallagher, UM Torian, AK Harris
Functions of HRP2 and capsid in positioning HIV-1 integration
Author(s): PK Singh, SH Hughes, HL Levin
Structural Analysis of Influenza Virus Hemagglutinin-induced Hemifusion by Volta Phase-Plate Cryo-electron Tomography
Author(s): P Chlanda, E Mekhedov, H Waters, CL Schwartz, ER Fischer, RJ Ryham, FS Cohen, PS Blank, J Zimmerberg
Human t-cell lymphocyte virus-1 (HTLV-1) proviral load and viral gene expression in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients
Author(s): A Vellucci, B Caruso, Y Enose-Akahata, J Ohayon, J Billioux, S Azodi, S Jacobson