How to Access Resources at the Center for Human Immunology

Authors

• CHI Consortium

Abstract

The Center for Human Immunology, Autoimmunity and Inflammation (CHI) was established as a trans-NIH Center in 2008. The mission of CHI is based on cooperative research, technologically driven with the goal of understanding human immunology, and addressing pathophysiologically-related human diseases. CHI provides specific technologies often unavailable to individual laboratories because of cost, complexity, and novelty, including multiplexed immune cell assays, and the application of advanced biostatistical and computer modeling methods for mining these diverse data to aid in understanding immune function and pathology. Investigators across NIH, regardless of Institute, are welcome to submit proposals for collaboration to CHI. Collaborative proposals are stringently vetted through multiple rounds of review but if accepted, CHI covers the majority of the cost of studies which typically range from $50,000 to $500,000. A typical project at CHI can last 1 to 5 years from inception to completion. It is not unusual for projects to contain up to several hundred separate samples, which are then analyzed by multiple highly complex multiplex platforms (e.g., Flow Cytometry, Genomics, and Protein Analysis) that produce thousands of data points. These data are first passed through a quality control pipeline and then analyzed by our bioinformatics team according to platform and ultimately in a synthetic manner using the tools of modern systems biology.

Scientific Focus Area: Research Support Services

This page was last updated on Friday, March 26, 2021