NIH Research Festival
Chair: David F. Stroncek, M.D. (CC)
Cell therapies have been used in clinical trials for more than 25 years, but until recently, their effectiveness and clinical application has been limited. The NIH intramural program is well suited to develop and translate novel cell therapies in early phase clinical trials. The results of many of these trials have been promising and some have advanced to later phase clinical trials. This symposium will highlight advances being made by intramural investigators in the fields of cancer immunotherapy, gene therapy, and regenerative medicine and the unique role of the Clinical Center and intramural program in the rapidly emerging field of cell-based therapies.
Chair: Robert S. Adelstein, M.D. (NHLBI)
Developmental biology aims to understand how an organism develops—how a single cell becomes an organized grouping of cells that is then programmed at specific times to become specialized for certain tasks. Genes control much of an organism’s development, but environmental stimuli also play a role, resulting in the complex “nature vs. nurture” paradigm. Intramural Research Program (IRP) investigators seek a deeper understanding of human development and the many disorders and diseases that can occur when normal development is disrupted. The purpose of this symposium is to inform the NIH community of the breadth of research in Developmental Biology being carried at the NIH in different laboratories, using a variety of animal species to model human biology.
Moderator: Brant M. Weinstein, Ph.D. (NICHD)
FAES Classrooms 1-4
Co-chairs: Kenneth H. Fischbeck, M.D. (NINDS) and Sharon A. Savage, M.D. (NCI-DCEG)
The genomics era has led to exciting discoveries in human clinical genetics that have greatly improved our understanding of the etiology of rare and common diseases. This symposium will highlight studies incorporating clinical characterization at the NIH Clinical Center with discovery of their genetic etiology. The topics range of topics discussed this symposium including neuromuscular disease, cancer predisposition syndromes, and immunodeficiency are meant to illustrate the breadth and depth of such studies in the intramural research program and highlight opportunities for collaboration.
FAES Classrooms 6-7
Co-chairs: Veronica A. Alvarez, Ph.D. (NIAAA) and Philip Shaw, Ph.D. (NHGRI)
Co-chairs: Mark R. Cookson, Ph.D. (NIA) and Yong-Chen William Lu, Ph.D. (NCI-CCR)
This symposium will highlight the application of single cell genomics across many different areas of biomedical interest. We will discuss a variety of exciting cellular and genomics techniques used as well as the challenging but informative informatics analyses that can be applied in this area. We hope that the audience will see opportunities to apply single cell techniques to their own research questions.
Chair: Yasmine Belkaid, Ph.D. (NIAID)
Symposia description forthcoming
FAES Classrooms 1-4
Co-chairs: Adrian Ferré-D’Amaré, Ph.D. (NHLBI) and Sandra L. Wolin, M.D., Ph.D. (NCI-CCR)
DNA serves as the repository for genetic information, and proteins are the biochemical machines of the cell. RNA is remarkable, being able to carry out both functions. This biochemical and structural versatility gives rise to diverse cell biological roles ranging from catalysis to the regulation of chromatin structure and gene expression. Because of its many critical functions, RNA has emerged as an important target for therapeutic intervention. In this session, advances in fundamental RNA biology, structure-based engineering, and pharmacological targeting of RNA in the NIH intramural program will be presented.
This page was last updated on Monday, March 15, 2021