Multidisciplinary Extreme Team Approach to Developing Translational Medicine Computer Systems

Authors

• Jim DeLeo

Abstract

A multidisciplinary extreme team (MET) approach to developing translational medicine computer systems is described. The MET approach has evolved from experience gained in the NIH Clinical Center Scientific Computing Section while working on NIH Intramural projects. A MET refers to a team that has all the necessary talent to do the required work. MET members work rapidly, interactively and cooperatively to realize project objectives. “Translational medicine computer systems” (TMCS) refers to computer systems designed for use in real-world settings to improve health. Major aspects of the MET approach include (1) starting with a good idea for a practical and useful TMCS, (2) defining clear objectives in developing the TMCS, (3) forming and managing an appropriate MET, (4) obtaining and wrangling relevant data, (5) developing, training, validating and testing proper computational methodologies, and (6) developing, implementing and monitoring the resulting production system. An important overarching feature of the MET approach is the continuous monitoring for bottlenecks that could impede progress and once identified, taking immediate action to alleviate them.

Scientific Focus Area: Research Support Services

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