The Imaging Probe Development Center (IPDC)makes imaging probes for the NIH intramural community and their collaborators

Authors

• H Wu
• F Bhattacharyya
• B Blackman
• V Coble
• C Hitko
• K Lane
• C Mushti
• A Opina
• N Raju
• D Sail
• Z Shi
• O Vasalatiy
• B Xu
• X Zhang
• R Swenson

Abstract

The Imaging Probe Development Center (IPDC) at NIH was founded as part of the 2003 trans-NIH Roadmap for Medical Research initiative with the aim of providing essential synthetic chemistry support needed to advance molecular imaging technologies in interdisciplinary research at basic through translational to clinical levels at NIH. The IPDC laboratories are located in Rockville, MD and on the Bethesda main campus with state-of-the-art equipment and scientists drawn from diverse backgrounds with expertise in synthetic, radiochemical, nanoparticle and conjugation chemistries. The IPDC has a rolling solicitation system and NIH scientists are welcome at any time to enquire about obtaining a probe in which they are interested. The IPDC has been working with principal investigators from more than a dozen NIH Institutes and Centers to produce a variety of imaging probes that are already known but otherwise unavailable, or are completely novel. Probes can be intended for all types of imaging modalities including MRI, optical fluorescence and PET/SPECT. Examples of molecular imaging probes we have made range from various complexes for MRI studies, fluorogenic enzyme substrates, fluorescent dyes and analogs, caged derivatives, radio- and fluorescent-labeled antibodies and other proteins, radiolabeled low molecular weight compounds, liposomes, dendrimers and nanoparticles. For more information, or to make inquiries about probe availability you may visit our website: http://www.nhlbi.nih.gov/research/intramural/researchers/programs/imaging-probe-development-center.

Scientific Focus Area: Research Support Services

This page was last updated on Friday, March 26, 2021