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NIH Research Festival

September 16 – 18, 2015

SBR-Blood: Systems Biology Repository for Hematopoietic Cells

Thursday, September 17, 2015 – Poster Session II
12:00 – 1:30 p.m.

FAES Terrace

NHGRI

SYSBIO-3

Authors

  • J Lichtenberg
  • EF Heuston
  • T Mishra
  • CA Keller
  • RC Hardison
  • DM Bodine

Abstract

Extensive research into hematopoiesis (the development of blood cells) over several decades has generated large sets of expression and epigenetic profiles in multiple human and mouse blood cell types. However, there is no single location to analyze how gene regulatory processes lead to different mature blood cells. We have developed a new database framework called hematopoietic Systems Biology Repository, or SBR-Blood, that allows user-initiated analyses for cell type correlations or gene-specific behavior during differentiation using publicly available datasets for array- and sequencing-based platforms from hematopoietic cells. SBR-Blood organizes information by both cell identity and by hematopoietic lineage. The validity and usability of SBR-Blood has been established through the reproduction of workflows relevant to expression data, DNA methylation, histone modifications and transcription factor occupancy profiles. SBR-Blood is accessible at http://sbrblood.nhgri.nih.gov.

Scientific Focus Area: Systems Biology

This page was last updated on Friday, March 26, 2021

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Download the 2015 Research Festival Schedule Overview (6 pages)

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Current Research Festival

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  • 2024
    • General Schedule of Events
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    • Special Wednesday Events
    • Vendor Exhibit Information
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  • 2023
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    • NIH Early–Career Investigator Lectures
    • Poster Sessions
    • Concurrent Workshops
    • NIH Resource Information Fair
    • Vendor Exhibit Information
    • Research Festival Committee
  • 2021
  • 2019
    • General Schedule of Events
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    • Poster Session
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    • Technical Sales Association (TSA) Research Festival Exhibit Tent Show
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