Compact video system for automated mouse home cage activity and behavior monitoring

Authors

• G Salem
• M Garmendia-Cedillos
• T Jones
• S Qin
• S Arumugam
• I Farooq
• L Wilson
• S Bradley
• D Kendricks
• Y Chudasama
• J Cushman
• D Coble
• J Dennis
• T Pohida

Abstract

Video monitoring of mice in the home-cage unveils behavior profiles without the restraints associated with specialized test equipment and disruptions caused by human interference. It is also key for behavior that is sensitive to changes in circadian rhythms which require long-term observations in their home environment. We present a system for video monitoring in the home-cage that allows for unrestrained activity and behavior in the mouse over long-time scales. The system is designed for integration with Allentown NexGen ventilated racks but can also be operated out of rack. The system has an easy to duplicate and assemble home-cage design along with a video acquisition solution. The system utilizes a depth video camera, and we demonstrate the robustness of depth video for home-cage mice monitoring. For researchers having no access to Allentown NexGen ventilated racks, we provide designs and assembly instructions for a standalone non-ventilated rack solution that holds three systems for more compact and efficient housing. Algorithms are being developed to automatically quantify activity and behavior for mice.

Scientific Focus Area: Biomedical Engineering and Biophysics

This page was last updated on Tuesday, August 6, 2024