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NIH Research Festival

September 12 – 14, 2018

Microfabricated structures for biology

Thursday, September 13, 2018 – Poster Session IV
3:30 – 5:00 p.m.

FAES Terrace

NIBIB

BIOENG-9

Authors

  • NY Morgan
  • S Kantesaria
  • W Wulftange

Abstract

Microfabricated devices with dimensions ranging from a few microns to a millimeter can now be routinely made out of biocompatible materials including glass, thermoplastics, elastomers, and hydrogels. Such devices can be particularly useful for cellular studies, defining microenvironments at lengthscales that mimic in vivo structures on platforms compatible with high-resolution optical imaging. Using our on-campus microfabrication facility, we have made a number of devices in close collaboration with other intramural groups, using an iterative design process. This poster will discuss a few examples that highlight the potential range of applications, including: a bioreactor system that uses a multiwell plate format, in which an oxygen-transmissive membrane, patterned with arrays of micropillars spaced at typical intercapillary distances, controls gas exchange for 3D cell culture; and the use of microfluidic droplet generators to generate hydrogel beads, and encapsulate cells, with applications ranging from improved culture models to high-throughput single-cell sequencing. In addition, we provide an overview of fabrication techniques and design considerations for researchers interested in using customized microdevices in their own work.

Scientific Focus Area: Biomedical Engineering and Biophysics

This page was last updated on Friday, March 26, 2021

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2018 program

Download the 2018 Research Festival Schedule Overview (6 pages)

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Current Research Festival

  • 2025
  • 2024
    • General Schedule of Events
    • 2024 NIH Distinguished Scholars Program
    • Poster Sessions
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    • NIH Resource Information Fair
    • National Academy of Science Mini-Symposium
    • Special Wednesday Events
    • Vendor Exhibit Information
    • Green Labs Fair
    • Research Festival Committee
  • 2023
    • General Schedule of Events
    • NIH Early–Career Investigator Lectures
    • Poster Sessions
    • Concurrent Workshops
    • NIH Resource Information Fair
    • Vendor Exhibit Information
    • Research Festival Committee
  • 2021
  • 2019
    • General Schedule of Events
    • Plenary Sessions
    • Poster Session
    • Data Blitz
    • FARE Award Ceremony
    • Special Exhibits on Resources for Intramural Research
    • Technical Sales Association (TSA) Research Festival Exhibit Tent Show
    • Research Festival Committee
  • 2018
    • General Schedule of Events
    • Plenary Sessions
    • Concurrent Symposia Sessions
    • Poster Sessions
    • FARE Award Ceremony
    • Special Exhibits on Resources for Intramural Research
    • Technical Sales Association (TSA) Research Festival Exhibit Tent Show
    • Research Festival Committees
  • 2017
    • General Schedule of Events
    • Plenary Sessions
    • Concurrent Symposia Sessions
    • Poster Sessions
    • FARE Award Ceremony
    • Future Research Leaders
    • Special Exhibits on Resources for Intramural Research
    • Technical Sales Association (TSA) Research Festival Exhibit Tent Show
    • Research Festival Committees
  • 2016
    • General Schedule of Events
    • Plenary Sessions
    • Concurrent Symposia Sessions
    • Poster Sessions
    • Browse by Presenter Name
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    • FARE Award Ceremony
    • Future Research Leaders
    • Special Exhibits on Resources for Intramural Research
    • Technical Sales Association (TSA) Research Festival Exhibit Tent Show
    • Tours of the National Library of Medicine and Clinical Center
    • Research Festival Committees
  • 2015
    • General Schedule of Events
    • Plenary Sessions
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    • Browse by Presenter Name
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