Empowering your research with services from the CCR Genomics Core

Authors

  • S Shema
  • Q Wei
  • D Tillo
  • M Wong
  • E Conner

Abstract

CCR Genomics Core under the Office of Science Technology Resource (OSTR) at the National Cancer Institute provides investigators with access to genomic technologies and Next-Generation Sequencing (NGS) with rapid turnaround on smaller-scale projects or projects that are not ready for production. The Core has an open-door policy operating more like a "boutique" and is unique in granting user-accessible instrumentation. Additional resources include training, consultation services, bioinformatics support, and secure data delivery/management. The Core supports 9 different platforms with 20 instruments supporting most of the CCR laboratories at the NIH Bethesda campus and multiple NIH institutes. Core instrumentation and services include Sanger Sequencing (2 ABI 3500xL Genetic Analyzers), Next-Generation Sequencing (Illumina: 1-iSeq, 1-MiSeq, 4- NextSeq2000), Long-Read and Whole Plasmid Sequencing (Oxford Nanopore MinION, GridION & PromethION2), Digital Gene Expression (Nanostring nCounter Analysis System), Digital Droplet PCR (Bio-Rad QX200 Droplet Digital PCR System), DNA/RNA & Library QC (Agilent TapeStation 4150 & 4200, Fragment Analyzer, Qubit), QuantStudio RT-PCR system, Pippin HT and Digital Spatial Profiling (NanoString GeoMx DSP). The DSP platform combines spatial and molecular profiling technologies by generating digital whole transcriptomes and profiling data. This technology is offered in collaboration with the Spatial Imaging Technology Resource (SpITR). In addition, the CCR Genomics Core functions as a support lab, containing instruments for various applications for use by CCR investigators. Analytical software for the various technologies is also made available. To learn more about our services visit us in Bldg. 41/Room D310 or our website at https://ostr.ccr.cancer.gov/resources/ccr-genomics-core/.

Scientific Focus Area: Research Support Services

This page was last updated on Tuesday, August 6, 2024

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