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Poster Sessions

Poster Session I  •  Poster Session II  •  Poster Session III  •  Poster Session IV  

Poster Session I
Monday, September 22, 2014 — 12:00 p.m. – 2:00 p.m. — FAES Academic Center

Attenuation of insula response to alcohol cues by varenicline in heavy drinkers: association with alcohol self-administration
Author(s): JL Gowin, V Vatsalya, ML Schwandt, R Momenan, ME Coe, ML Cooke, S Bartlett, M Heilig, VA Ramchandani

NIAAA

BEHAV-1

A developmental examination of face emotion labeling
Author(s): AH Oakes, JL Wiggins, NE Adleman, P Kim, MA Brotman, E Leibenluft

NIMH

BEHAV-2

Greater Mastery is Associated with Psychological Resistance and Recovery in Assaulted Women and Related to Maintenance of Physical Health
Author(s): HL Rusch, E Shvil, SL Szanton, Y Neria, JM Gill

NINR

BEHAV-3

Preterm birth in the context of increasing income inequality
Author(s): ME Wallace, P Mendola, Z Chen, BS Hwang, KL Grantz

NICHD

BEHAV-4

Latent Class Analysis of Non-Treatment Seeking Social Drinkers Reveal 3 Empirical Classes with Differences in Risk for Alcohol-Related Phenotypes
Author(s): J Yan, ML Schwandt, SB Cho, BL Stangl, LE Kwako, DM Dick, KS Kendler, L Leggio, R Momenan, M Heilig, VA Ramchandani

NIAAA

BEHAV-5

Application of multi-spectral imaging method for assessing the efficacy of treatment in Cushings’ Syndrome
Author(s): A Afshari, Y Ardeshirpour, MB Lodish, E Gourgari, M Keil, F Chowdry, E Belyavskaya, C Lyssikatos, V Chernomordik, CA Chernomordik, AH Gandjbakhche

NICHD

BIOENG-1

Relationship between cerebral hemodynamics and age in the prefrontal cortex: A pilot study using Functional Near Infrared Spectroscopy in children
Author(s): AA Anderson, V Chernomordik, F Chowdry, A Thurm, E Smith, D Black, D Matthews, AH Gandjbakhche

NICHD

BIOENG-2

Monitoring the efficacy of targeted therapy using in vivo time-resolved fluorescence imaging
Author(s): Y Ardeshirpour, V Chernomordik, M Hassan, R Zielinski, J Capala, AH Gandjbakhche

NICHD

BIOENG-3

Biomedical Engineering and Physical Science Shared Resource
Author(s): HS Eden, AJ Balbo, EK Dimitriadis, AM Gorbach, HR Kalish, NY Morgan, G Zhang

NIBIB

BIOENG-4

Cancer cell mRNA localization during metastasis
Author(s): SM Hamilla, S Mili

NCI

BIOENG-5

Relative Brain Signature (RBS): A population-based feature extraction technique to identify functional biomarkers in the brain of alcoholic subjects
Author(s): N Karamzadeh, M Kellman, A Anderson, F Chowdhry, Y Ardeshirpour, D Chorlian, E Wegman, A Gandjbakhche

NICHD

BIOENG-6

Microfabricated structures for biology
Author(s): NY Morgan, DE da Silva, AM Taverner, JS Yoon

NIBIB

BIOENG-7

HIV-Tat protein enhances amyloid beta peptide aggregation and neurotoxicity
Author(s): A Popescu Hategan, J Steiner, E Karnaukhova, E Dimitriadis, A Nath

NINDS

BIOENG-8

Fluorescence Optical Sedimentation Velocity With Photoswitchable Proteins
Author(s): P Schuck, J Ma, G Patterson, H Zhao

NIBIB

BIOENG-9

Automated lymphadenopathy detection by sparse linear fusion of 2D views
Author(s): A Seff, L Lu, K Cherry, H Roth, J Liu, S Wang, E Turkbey, R Summers

CC

BIOENG-10

Tumor growth prediction with hyperelastic biomechanical model, physiological data fusion, and nonlinear optimization
Author(s): K Wong, R Summers, E Kebebew, J Yao

CC

BIOENG-11

Global Analysis of Data from Multiple Biophysical Methods for the Analysis of Protein Complex Stoichiometry and Affinity
Author(s): H Zhao, J Ma, P Schuck

NIBIB

BIOENG-12

SCCPDH regulates early brain development in zebrafish
Author(s): EA Burke, WA Gahl, CF Boerkoel

NHGRI

DEVBIO-1

Sea2, a new regulator of metabolism and autophagy, is required for oogenesis in Drosophila
Author(s): W Cai, MA Lilly

NICHD

DEVBIO-2

VEGFR1: a developmental link between neuronal migration and vasculogenesis
Author(s): EM Flannery, D Donohue, S Wray

NINDS

DEVBIO-3

Differences in genomic epigenetic signatures of coding and long non-coding RNA genes in mouse erythroblasts and megakaryocytes
Author(s): EF Heuston, J Lichtenberg, SM Anderson, M Kirby, CK Capone, V Paralkar, RC Hardison, M Weiss, DM Bodine

NHGRI

DEVBIO-4

How do hypoxia-responsive factors such as CXCL12, VEGF-A and EPO regulate the vascular branching morphogenesis during neuro-vascular wiring formation?
Author(s): W Li, Y Mukouyama

NHLBI

DEVBIO-5

Sox9/β-catenin Double Knockout Mice Uncover a New Paradigm in Testis Differentiation
Author(s): B Nicol, H Yao

NIEHS

DEVBIO-6

TGFß signaling positively regulates lymphatic endothelial cell sprouting in vitro
Author(s): BT Shepherd, JM James, YS Mukouyama

NHLBI

DEVBIO-7

The Drosophila Nprl2/Nprl3 complex controls the response to nutrient stress by modulating TORC1 activity
Author(s): Y Wei, MA Lilly

NICHD

DEVBIO-8

Identifying and isolating thyroid hormone-target cells in tissues
Author(s): XF Wu, H Liu, YL Fu, L Ng, D Forrest

NIDDK

DEVBIO-9

Neuro-vascular wiring in obese mice
Author(s): T Yamazaki, W Li, Y Mukouyama

NHLBI

DEVBIO-10

Alcohol-preferring P rats do not exert higher compulsive drinking despite increased motivation to consume alcohol
Author(s): E Augier, H Sun, M Heilig

NIAAA

NEURO-1

Neuronal DNA-methylation in the medial prefrontal cortex regulates alcohol-induced behavior and plasticity
Author(s): E Barbier, JD Tapocik, N Juergens, C Pitcairn, A Borich, JC Hanson, JR Schank, H Sui, A Thorsell, K Schuebel, Z Zhou, Q Yuan, M Emmert-Buck, D Goldman, M Heilig

NIAAA

NEURO-2

Role of histone modifying enzyme PRDM2 in alcohol-related behaviors
Author(s): E Barbier, C Pitcairn, A Borich, J Tapocik, A Johnstone, J Schank, Z Zhou, Q Yuan, D Goldman, C Wahlestedt, M Heilig

NIAAA

NEURO-3

The Dorsolateral Striatum Competes with Visual Discrimination Learning
Author(s): HC Bergstrom, CL Pickens, CR Pinard, O Bukalo, LR Halladay, A Holmes

NIAAA

NEURO-4

Drug-induced activation of a Gs-coupled designer GPCR in hypothalamic AgRP neurons stimulates chronic food intake and weight gain in mice
Author(s): Z Cui, K Nakajima, C Li, M Krashes, B Lowell, J Wess

NIDDK

NEURO-5

Striatal dopamine D2 receptor expression, physical activity, and weight gain
Author(s): K Devarakonda, DM Friend, KD Hall, AV Kravitz

NIDDK

NEURO-6

D2-dopamine receptors and the development of obesity
Author(s): DM Friend, K Devarakonda, JC Lemos, A Kaplan, VA Alvarez, AV Kravitz

NIDDK

NEURO-7

Antidepressant treatment inhibits fear via brain endocannabinoids
Author(s): O Gunduz-Cinar, S Flynn, R Cinar, T Ramikie, S Patel, G Kunos, A Holmes

NIAAA

NEURO-8

Switching between top-down and bottom-up attention in a patient with right MFG tumor resection
Author(s): KA Holiday, SA Japee, MD Satyshur, I Mukai, LG Ungerleider

NIMH

NEURO-9

The role of glutamatergic synaptic transmission onto midbrain dopamine neurons in reward-related behaviors
Author(s): MA Hutchison, MR Lee, W Lu

NINDS

NEURO-10

Representations of face size, identity, and viewing angle in anterior fundus (AF) face patch
Author(s): AP Jones, LN Vasileva, DBT McMahon, IV Bondar, DA Leopold

NIMH

NEURO-11

Effects of chronic intermittent ethanol vapor exposure in adolescent and female mice
Author(s): NJ Jury, A Holmes

NIAAA

NEURO-12

An shRNA-based in vivo retina screen identifies molecules that regulate presynaptic development of rod photoreceptor
Author(s): SY Kim, C Park, M Brooks, A Klingenhoff, R Villasmill, H Hong, R Farriss, T Cogliati, W Li, A Swaroop

NEI

NEURO-13

Dopamine type 2 receptor in dorsal striatum as a regulator of perceptually guided versus memory guided decision making
Author(s): E Lee, O Dal Monte, BB Averbeck

NIMH

NEURO-14

Fronto-amygdala resting state functional dysconnectivity is associated with age in bipolar disorder
Author(s): S Lever, D Hsu, J Stoddard, MA Brotman, M Ernst, DS Pine, E Leibenluft, D Dicktein

NIMH

NEURO-15

The underlying neural network of proopiomelanocortin (POMC)-mediated regulation in food intake
Author(s): C Li, MJ Krashes

NIDDK

NEURO-16

A new non-invasive method for detecting retinal vasculature using blue reflectance scanning laser ophthalmoscope
Author(s): Y Li, L Zhao, W Wong, H Qian

NEI

NEURO-17

Associations between irritability and neural activity during a frustrating attentional task
Author(s): LS Machlin, W-L Tseng, CM Deveney, K Towbin, DS Pine, MA Brotman, E Leibenluft

NIMH

NEURO-18

Presenilin 1 Mutations impair neuronal Bioenergetics and dietary Energy Restriction ameliorates cognitive Deficits caused by a Presenilin 1 Mutation
Author(s): C Maharana, R Cutler, B Wustman, A Stevens, M P Mattson

NIA

NEURO-19

Effects of age and tissue composition on GABA levels measured with magnetic resonance spectroscopy in the prefrontal cortex in healthy volunteers
Author(s): CT Meyer, S Kuo, JW van der Veen, AS Barnett, DR Weinberger, KF Berman, S Marenco

NIMH

NEURO-20

Differential binding of receptor protein tyrosine phosphatase type IIa family (RPTPσ/RPTPδ/LAR) to glycosaminoglycans
Author(s): AA Morgan, Y Katagiri, P Yu, NJ Banayan, R Junka, HM Geller

NHLBI

NEURO-21

Examining the neural correlates of irritability during frustrating feedback using dimensional and categorical approaches
Author(s): EC Moroney, W-L Tseng, CM Deveney, K Towbin, DS Pine, MA Brotman, E Leibenluft

NIMH

NEURO-22

Behavior bests brain as an Autism Spectrum Disorder biomarker
Author(s): M Plitt, KA Barnes, GL Wallace, IW Eisenberg, B Orionzi, L Kenworthy, SJ Gotts, A Martin

NIMH

NEURO-23

Decreased protein synthesis in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of mTORC1 activation
Author(s): RM Reith, T Huang, M Qin, CB Smith

NIMH

NEURO-25

Development of longitudinal two-photon imaging in awake marmosets: an optical technique for studies of cerebral microcirculation and neuronal activation in primates
Author(s): TP Santisakultarm, JL Ciuchta, S Choi, J Park, LD Notardonato, AC Silva

NINDS

NEURO-26

Neural correlates of implicit face-emotion processing in youth with severe irritability
Author(s): B Sharif-Askary, J Stoddard, P Kim, J Yi, K Hinton, MA Brotman, D Pine, E Leibenluft

NIMH

NEURO-27

Regionally selective decline in hippocampal somatostatin-immunoreactive neuron number in aged rhesus monkeys with memory impairment
Author(s): AM Spiegel, EJ Perez, JM Long, P Park, PR Rapp

NIA

NEURO-28

Varenicline effects on amygdala in response to fearful faces in heavy drinkers
Author(s): JG Westman, JL Gowin, V Vatsalya, M Schwandt, R Momenan, ME Coe, MC Cooke, S Bartlett, M Heilig, VA Ramchandani

NIAAA

NEURO-29

Regulatory Fatigue Syndrome: A Novel Approach to a Weary Condition
Author(s): SM Albert, SL Kopka, TJ Miller, DG Chaitt, JF Pierson

NIAID

RSCHSUPP-1

Laboratory Animal Sciences Program at the Frederick National Laboratory for Cancer Research
Author(s): M Anver, P Awasthi, S Difilippantonio, P Gorelick, W Hsieh, J Kalen, R Sriperumbudur, L Sternberg

NCI

RSCHSUPP-2

Safe science is good science
Author(s): R Augustin, M G Shue

OD

RSCHSUPP-3

The National Cancer Institute Specimen Resource Locator
Author(s): J P Demchok, R Chuaqui, S Marroulis, A Glass, B Fombonne, S Taube, I Lubensky

NCI

RSCHSUPP-4

Education, training, boot camps, lab techniques, leadership and management seminars, conferences and memorial lectures, and mentoring
Author(s): C Farias

OD

RSCHSUPP-5

Supporting scientific reproducibility through effective data management: The NIH Library’s role
Author(s): LM Federer

OD

RSCHSUPP-6

Careers for scientists in technology transfer & business development
Author(s): SM Ferguson

OD

RSCHSUPP-7

NIH and the Federal Laboratory Consortium for Technology Transfer
Author(s): SM Ferguson, GK Jones

OD

RSCHSUPP-8

Student training and fellowship opportunities at the National Cancer Institute at Frederick
Author(s): A Frydl, J Hartman, M Porter

NCI

RSCHSUPP-9

Transitioning from Paper to Electronic Format:Lessons Learned from Regulatory eCTD Submissions
Author(s): LH Giambarresi, SC Garrand, MA Chakrabarti, VS Eccard, AL Gonzalez, ML Baracz, LM Lacuesta, MJ Buehn

NIAID

RSCHSUPP-10

CDR – an IT System Managing Biospecimen Collection
Author(s): P Guan, C Shive, L Qi, P Hariharan, S Wu, K Um, V Santhanam, P Kigonya, J McLean, J Vaught, HM Moore

NCI

RSCHSUPP-11

HPC Web+: An open and shareable application for simplifying scientific computing
Author(s): O Juarez-Espinosa, A Levitsky, J Dommer, R Kaur, N Weber, Y Huyen

NIAID

RSCHSUPP-12

The Biospecimen Research Database: Upgraded
Author(s): JC Keen, K Engel, S Greytak, BP Bass, P Guan, HM Moore

NCI

RSCHSUPP-13

NIH Mouse Imaging Facility - a multi-modal animal imaging facility for the intramural NIH research community
Author(s): BA Klaunberg, ML Lizak, HD Morris, JP Munasnghe, DP DesPres, VM Diaz, DR Donahue

NINDS

RSCHSUPP-14

NCI Policy and Compliance Programs in Support of Research: Risk Management, PRA/OMB Clearance and Records Management
Author(s): L Larson, K Bailey, A Holliday

NCI

RSCHSUPP-15

Bibliometrics at the NIH Library: a portfolio analysis of NHLBI publications (2008-2012)
Author(s): Y Lu

OD

RSCHSUPP-16

Stopping NIAID clinical trials for safety
Author(s): T Mainprize, B Eagel

NIAID

RSCHSUPP-17

Managing Laboratory Chemicals Made Simple
Author(s): E R Reid, CG Campos, J Glass, LV Kibiuk, C Hernandez, D E Wilson

OD

RSCHSUPP-18

Performance comparison of MEDLINE structured abstracts to unstructured abstracts
Author(s): AM Ripple, JG Mork, HJ Thompson, SC Schmidt, LS Knecht

NLM

RSCHSUPP-19

A Systems Approach to Modeling Work Flow Efficiencies in Task Distribution and Response Collection (Towards Promoting Service Quality and Customer Satisfaction)
Author(s): S Weiss, Y Li, L McNay

NIAID

RSCHSUPP-20

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Poster Session II
Monday, September 22, 2014 — 4:00 p.m. – 6:00 p.m. — FAES Academic Center

Selective chromatid segregation mechanism invoked for the human congenital mirror hand movement disorder development by RAD51 mutations: A Hypothesis
Author(s): Amar Klar

NCI

CHROM-1

Comprehensive analysis of the DNA methylation mutant Hells-/- reveals de-repression of repeat elements and redundant pathway for silencing of protein-coding genes
Author(s): W Yu, C McIntosh, R Lister, I Zhu, Y Han, J Ren, D Landsman, E Lee, JR Ecker, K Muegge

NCI

CHROM-2

A Replicator-Specific Binding Protein Essential For Initiation of DNA Replication in Mammalian Cells
Author(s): Y Zhang, L Huang, HQ Fu, CM Lin, OK Smith, K Utani, MI Aladjem

NCI

CHROM-3

Analyzing the 3D Architecture of Pancreatic Islets of Langerhans by Serial Block Face SEM
Author(s): MA Aronova, CR Pfeifer, A Shomorony, G Zhang, RD Leapman

NIBIB

DIR-1

The Systems Biology of the Mitochondrion
Author(s): RS Balaban

NHLBI

DIR-2

NF45 Modulates Induction of Interferon Beta and Interacts with the Dengue Virus Capsid Protein
Author(s): C Balinsky, H Schmeisser, KC Zoon

NIAID

DIR-3

Modeling Evolutionary Conserved Human Insulin Receptor Mutations in the Worm
Author(s): D Bulger, T Fukushige, R Semple, J Hanover, M Krause

NIDDK

DIR-4

Effect of environment on the long-term consequences of chronic pain
Author(s): MC Bushnell, M Ceko, V Cotton, JL Gracely, LA Low, MH Pitcher, C Villemure

NCCAM

DIR-5

Pro-inflammatory state: A hallmark of accelerated aging
Author(s): L Ferrucci

NIA

DIR-6

Direct bioluminescent imaging of ABCG2 function at the blood-brain barrier using the specific substrate D-luciferin
Author(s): M Gottesman, MD Hall, J Bakhsheshian, B Wei, RM Simpson

NCI

DIR-7

Down-modulation of tumor suppressor p53 by T cell receptor signaling is critical for antigen-specific CD4+T cell responses
Author(s): M Watanabe, K Moon, MS Vacchio, KS Hathcock, R J Hodes

NIA

DIR-8

To be determined
Author(s): D Kastner

NHGRI

DIR-9

Advances in defining the factors and mechanisms controlling development and regeneration of periodontal tissues
Author(s): MJ Somerman, B Foster, L Wang, N Aomin, V Thumbigere-Math, H Xe, A Tran, C Willoughby, N KalantariPour, Dr Golberg and team, Dr Sanford-Burnham and team, Dr Millian and team, Dr Nociti and team, Dr Kantovitz and team, Dr Zweifler

NIDCR

DIR-10

Constitutive activation of PRKACA in adrenal Cushing's syndrome
Author(s): C Stratakis, F Beuschleni, M Fassnacht, G Assié, D Calebiro, FR Faucz, A Osswald, CL Ronchi, T Wieland, S Sbiera, K Schaak, A Schmittfull, T Schwarzmayr, O Barreau, D Vezzosi, M Rizk-Rabbin, U Zabel, E Szarek, P Salpea, A Forlino

NICHD

DIR-11

Investigating the roles of splicing factor mutations in lung adenocarcinomas and myeloid neoplasms
Author(s): D Liang Fei, S Prasad, J Yu, H Motowski, H Varmus

NCI

DIR-12

Yeast eIF4B binds the small ribosomal subunit and promotes mRNA recruitment during translation initiation.
Author(s): SE Walker, F Zhou, SF Mitchell, VS Larson, AG Hinnebusch, JR Lorsch

NIGMS

DIR-13

Exposure to Indoor Allergens in Relation to Asthma: Results from the National Health and Nutrition Examination Survey (NHANES)
Author(s): DC Zeldin, R Jaramillo, KM Rose, A Calatroni, HE Mitchell, PJ Gergen, R Cohn, ML Sever, SJ Arbes, PM Salo

NIEHS

DIR-14

Hydroxyurea-inducible SAR1 gene acts through the Giα/JNK/Jun pathway to regulate γ-globin expression
Author(s): J Zhu, K Chin, W Aerbajinai, C Kumkhaek, H Li, GP Rodgers

NIDDK

DIR-15

Hoyeraal Hreidarsson syndrome, a severe variant of dyskeratosis congenita, caused by biallelic mutations in TPP1
Author(s): BJ Ballew, H Kocak, K Bisht, JF Boland, BD Hicks, L Burdett, A Vogt, AA Hutchinson, N Giri, BP Alter, M Yeager, C Keegan, J Nandakumar, SA Savage

NCI

GEN-1

Complex dynamics of meiotic recombination initiation in laboratory mouse strains
Author(s): KM Brick, F Smagulova, G Petukhova, RD Camerini-Otero

NIDDK

GEN-2

RNAi knockdown of RAD51 in mouse testicular cells reveals its role in meiotic homologous recombination in mammals
Author(s): J Dai, S Potapova, O Voloshin, RD Camerini-Otero

NIDDK

GEN-3

Overall clinical impairment associated with rare copy number variants (CNVs) associated with neurodevelopmental disorders
Author(s): LA Friedman, LI Kasoff, K Ahn, JL Rapoport

NIMH

GEN-4

Functional characterization of FBXW7 mutations in endometrial cancer
Author(s): B Hong, ML Rudd, DW Bell

NHGRI

GEN-5

Comprehensive Clinical and Molecular Analysis of Trichothiodystrophy Patients with Mutations in the TTDN1 Gene
Author(s): S G Khan, E R Heller, D Tamura, J J DiGiovanna, K H Kraemer

NCI

GEN-6

Different yeast prions depend differently on functions of yeast Sis1 J-protein Hsp40
Author(s): CP Lin, B Roberts, DC Masison

NIDDK

GEN-7

Adeno-Associated Viral (AAV) Vector-Mediated Gene Therapy for X-linked Retinitis Pigmentosa (XLRP): A Long-Term Efficacy Study in Mouse Models of RPGR or RP2 Deficiency
Author(s): S Mookherjee, P Colosi, S Hiriyanna, K Kaneshiro, H Qian, M Campos, C Gao, R Fariss, H Khanna, T Li, A Swaroop, Z Wu

NEI

GEN-8

The interplay of cognition, culture, and virtual communities in translational research
Author(s): DM Mosbrook-Davis, JM Guzman, M Sincan, CS Marcum, AE Links, EE Lee, DD Draper, DR Adams, EF Macnamara, WA Gahl, CF Boerkoel

NHGRI

GEN-9

Common variation in a putative regulatory region of STAM2 is associated with skeletal muscle expression of STAM2 and increased risk for type 2 diabetes in American Indians
Author(s): AK Nair, RL Hanson, P Piaggi, N Mclean, YL Muller, K Huang, S Kobes, WC Knowler, C Bogardus, LJ Baier

NIDDK

GEN-10

Autosomal recessive Diamond-Blackfan anemia: Identification of mutations in MCM2, SEMA7A, and FLNB
Author(s): KA O'Brien, NE Seidel, JE Farrar, A Vlachos, NIH Intramural Sequencing Center, SM Anderson, X An, E Atsidaftos, HL Malech, RJ Arceci, SR Ellis, JM Lipton, DM Bodine

NHGRI

GEN-11

The yeast ISW1, CHD1 and RSC chromatin remodelers have additive effects on global chromatin structure
Author(s): J Ocampo, RV Chereji, PR Eriksson, DJ Clark

NICHD

GEN-12

Direct mapping of meiotic DSBs in human individuals: novel aspects of recombination initiation
Author(s): F Pratto, K Brick, P Khil, F Smagulova, G Petukhova, RD Camerini-Otero

NIDDK

GEN-13

Genome-wide association analysis identifies susceptibility loci for carotid intima-media thickness among African Americans
Author(s): SM Tajuddin, MA Nalls, MF Keller, AB Zonderman, MK Evans

NIA

GEN-14

High-throughput Targeted Mutagenesis using CRISPR/Cas9 in Zebrafish
Author(s): G K Varshney, W Pei, J Ledin, M LaFave, V Gallardo, J Idol, L Xu, M Jones, U Harper, B Carrington4, K Bishop, M Vemulapalli, M Li, W Chen, J Mullikin, R Sood, S M Burgess

NHGRI

GEN-15

Defining CTCF physiological roles: rules of the "CTCF code"
Author(s): L Vian, H Nakahashi, W Resch, KR Kieffer Kwon, A Oksanen, M Dose, N Pruett, S Nelson, J Qian, W Dubois, RD Phair, R Casellas

NIAMS

GEN-16

Germline variation modulates susceptibility to metastasis in a mouse model of prostate tumorigenesis
Author(s): KA Williams, S Bupp, S Patel, J Andreas, S Zhang, A Molinolo, S Gutkind, N Crawford

NHGRI

GEN-17

A fast and powerful tree-based association test for detecting complex joint effects in case-control studies
Author(s): H Zhang, W Wheeler, Z Wang, PR Taylor, K Yu

NCI

GEN-18

Carbonylated cardiac myosin binding protein C as an indicator of doxorubicin-induced cardiotoxicity
Author(s): B P Aryal, J Jeong, V A Rao

FDA/CBER

MOLBIO-1

Protein glycosylation: a factor in the pathology of PLAN?
Author(s): M Davids, MS Kane, M He, CF Boerkoel, WA Gahl, C Torro

NHGRI

MOLBIO-2

Amyloid triangles, squares, and loops of apolipoprotein C-III
Author(s): M de Messieres, R K Huang, Y He, J C Lee

NHLBI

MOLBIO-3

Follicle Stimulating Hormone (FSH) Induction of Aromatase and Luteinizing Hormone Receptor (LHR) is Dependent, in part, on the Protein Kinase A Regulatory-Rho-Guanine Nucleotide Exchange Factor AKAP13
Author(s): KM Devine, PH Driggers, SC Su, JH Segars

NICHD

MOLBIO-4

Inhibition of RPE65 retinol isomerase activity by inhibitors of lipid metabolism
Author(s): A EROGLU, S Gentleman, E Poliakov, TM Redmond

NEI

MOLBIO-5

In PDE3B KO Mice, White Epididymal Adipose Tissue (WAT) Exhibits Phenotypic Characteristics of "Fat-burning" Brown Adipose Tissue (BAT), with reduced expression of pro-inflammatory markers, including the NLRP3 Inflammasome
Author(s): FA Khan, YW Chung, Y Tang, SC Hockman, K Berger, EM Billings, O Gavrilova, E Guirguis, S Liu, Y Khan, K Huo, DM Schimel, AM Aponte, E Degerman, VC Manganiello

NHLBI

MOLBIO-6

A macro-histone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance
Author(s): S Khurana, M J Kruhlak, J Kim, AD Tran, J Liu, K Nyswaner, L Shi, P Jailwala, M Sung, O Hakim, P Oberdoerffer

NCI

MOLBIO-7

Post-transcriptional Regulation of C-reactive Protein by the RNA-binding Protein HuR
Author(s): Y Kim, N Noren Hooten, MK Evans

NIA

MOLBIO-8

Mechanistic insight to the Hsp90 chaperone by mutational analysis of conserved interaction sites
Author(s): AN Kravats, O Genest, JR Hoskins, S Wickner

NCI

MOLBIO-9

Role of LDB1 in the transition from chromatin looping to transcription activation
Author(s): Ivan Krivega, Ryan Dale, Ann Dean

NIDDK

MOLBIO-10

Nucleosome-binding protein HMGN4 increases oncogenic activity by inhibiting the expression of E2F-target genes
Author(s): JE Kugler, T Furusawa, M Bustin

NCI

MOLBIO-11

Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based reactive oxygen species generation and cell migration
Author(s): J Kwon, DJ Burke, A Wang, HE Boudreau, A Korzeniowska, YS Kim, L Li, S Jaeger, K Palaniappan, SH Jackson, TL Leto

NIAID

MOLBIO-12

Adenovirus-mediated overexpression of SOAT1 attenuates 7-ketocholesterol-induced cytotoxicity and inflammation in ARPE-19 cells
Author(s): JW Lee, IR Rodriguez

NEI

MOLBIO-13

Study of molecular cloning,purification and characterization of C.elegans Phosphodiesterase 3 (CEPDE3)isoforms
Author(s): SG Naik, A Samidurai, DK Rhee, F Ahmad, SC Hochman, N Carter, VC Manganiello

NHLBI

MOLBIO-14

Effects of heterologous expression of human cyclic nucleotide phosphodiesterase 3A (hPDE3A) on redox regulation in Yeast
Author(s): DK Rhee, JC Lim, S Hockman, F Ahmad, YW Chung, S Liu, A Hockman, V Manganiello

NHLBI

MOLBIO-15

Mitigating long-term cardiac adverse effects of radiation exposure: emerging opportunities in protein oxidation and autophagy modulation
Author(s): ET Rosen, Y Gonzalez, B Aryal, L Chehab, J Dickey, AV Rao

FDA/CBER

MOLBIO-16

Novel mouse models to probe the function of hepatic Gi signaling in maintaining glucose homeostasis
Author(s): M Rossi, L Zhu, SM McMillin, Y Cui, O Gavrilova, S Coughlin, MJ Birnbaum, J Wess

NIDDK

MOLBIO-17

Can Single-Molecule Structures be Defined in Vivo?
Author(s): JM Solis, A Nagy, F Buss, JR Sellers

NHLBI

MOLBIO-18

The NIDA/OTTC Plasmid Database: Developing a cost- and time-saving tool for archiving plasmid DNA
Author(s): G Sun, R Domingo, W Lau, C Johnson, C Richie, B Harvey

CIT

MOLBIO-19

A cAMP-specific phosphodiesterase, phosphodiesterase 8B (PDE8B), affects Sertoli cell proliferation in adult mice
Author(s): E Szarek, L Ferro Leal, M Kotula-Balak, B Bilinska, CA Stratakis

NICHD

MOLBIO-20

Methionine as a redox switch regulating biological activities of cofilin
Author(s): H Uehara, E Shacter, S Luo

FDA/CBER

MOLBIO-21

Hfqs and Small RNA Regulation in Bacillus anthracis: Protein Biochemistry and Transcriptomic Perspectives
Author(s): CE Vrentas, S Porcella, Z Hu, R Ghirlando, SH Leppla

NIAID

MOLBIO-22

The IA-2/IA-2β Intronic miRNA, miR-153, is Implicated in Insulin Secretion
Author(s): H Xu, L Abuhatzira, C Gilberto, AL Notkins

NIDCR

MOLBIO-23

Binge alcohol promotes hypoxic liver injury via CYP2E1-HIF-1α-dependent apoptosis pathway in mice and humans
Author(s): JW Yun, MJ Son, MA Abdelmegeed, A Banerjee, TR Morgan, SH Yoo, BJ Song

NIAAA

MOLBIO-24

Beta-arrestin-2 acts as a negative regulator of hepatic hepatic glucose production in vivo
Author(s): L Zhu, M Rossi, Y Cui, W Sakamoto, NM Urs, MG Caron, JH Wess

NIDDK

MOLBIO-25

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Poster Session III
Tuesday, September 23, 2014 — 12:00 p.m. – 2:00 p.m. — FAES Academic Center

Altered Epithelial Tight Junction Indicators in Non-alcoholic Fatty Liver Disease
Author(s): S Abey, P Smyser, N Fourie, L Sherwin, W Henderson

NINR

CLIN-1

Assessing body fatness in obese children and adolescents: alternative methods to dual-energy X-ray absorptiometry
Author(s): D Colley, B Cines, N Current, C Schulman, S Bernstein, AB Courville, KL Zambell, J Yanovski

CC

CLIN-2

Demonstrating the importance of repurposing data by focusing on end-point results
Author(s): J DeLeo

CC

CLIN-3

Self-reported responses to alcohol following oral and intravenous administration in humans: Does route of exposure matter?
Author(s): AM Durrani, S O'Connor, VA Ramchandani

NIAAA

CLIN-4

Responders and nonresponders in addiction treatment: Real-time daily-life stress reactivity differs more than trait coping
Author(s): MA Furnari, ML Jobes, KA Phillips, DH Epstein, KL Preston

NIDA

CLIN-5

Increasing throughput by automation of manual ELISA on robotic liquid handling platform
Author(s): J Govindharajulu, G Barger, A K Srivastava

NCI

CLIN-6

Computer-based training reduces a bias towards angry judgments
Author(s): EA Harkins, B Sharif-Askary, JS Stoddard, MA Brotman, E Leibenluft

NIMH

CLIN-7

Whole transcriptome expression profiles in lymphoblastoid cells from women with PMDD and controls: diagnostic differences and differential response to ovarian steroids
Author(s): JF Hoffman, N Dubey, K Schuebel, C Marietta, Q Yuan, PE Martinez, LK Nieman, DR Rubinow, PJ Schmidt, D Goldman

NIMH

CLIN-8

Clinical Research Informatics: Using CDISC Standards to Create Formal and Computable Representation of Human Clinical Research Protocols
Author(s): V Huser

CC

CLIN-9

Angiotensin Converting Enzyme Inhibitor Use is associated with improved in-hospital Survival among Intensive Care Unit Patients with Blood Borne Infections
Author(s): J Kimbrough, V Huser, J Cimino

NLM

CLIN-10

The Effect of Physical Activity on Headaches in Adolescents
Author(s): D Lameira, T Lateef, JP He, K Merikangas

NIMH

CLIN-11

The relationship between self-reported anxiety and autonomic arousal at fear conditioning & explicit memory at extinction recall
Author(s): AL McGlade, EJ Ivie, KJ Michalska, A Gold, T Shechner, DS Pine

NIMH

CLIN-12

Navigating Barriers to International Clinical Research through a Web-Based Tool
Author(s): Y Moghadam, G Goodman, J Andrews, M Smolskis, J Kagan

NIAID

CLIN-13

Anticipating evaluation from unpredictable peers is associated with differential brain response in socially anxious adolescents
Author(s): LH Russell, EE Nelson, DS Pine, JM Jarcho

NIMH

CLIN-14

Vascular inflammation by FDG PET-CT is associated with aortic wall Properties by MRI
Author(s): AS Sadek, J Dave, J Hasan, P Krishnamoorthy, S Rose, H Naik, E Weiner, MA Ahlman, DA Bluemke, NN Mehta

NHLBI

CLIN-15

Stromal derived factor-1a may help form aortopulmonary collateral vessels in cyanotic congenital heart disease
Author(s): N Sandeep, Y Mukouyama

NHLBI

CLIN-16

Lysozyme, microbial translocation and symptom severity in Irritable Bowel Syndrome
Author(s): LB Sherwin, NH Fourie, SK Abey, PA Smyser, B Rahim-Williams, Z Sun, X Wu, WA Henderson

NINR

CLIN-17

Characterization of operant intravenous alcohol self-administration in humans
Author(s): BL Stangl, J Westman, M Zametkin, VA Ramchandani

NIAAA

CLIN-18

The Evolution of eyeGENE®: The National Opthalmic Disease Genotyping and Phenotyping Network
Author(s): J B Yim, R C Cooper, A V Garafalo, K E Goetz, R S Parrish, M J Reeves, S J Tumminia

NEI

CLIN-19

Nitrate and nitrite ingestion and risk of ovarian cancer among postmenopausal women in Iowa
Author(s): M Inoue-Choi, RR Jones, KE Anderson, KP Cantor, JR Cerhan, S Krasner, K Robien, PJ Weyer, MH Ward

NCI

EPIG-2

Modeling fine particulate matter along the Gulf Coast from the Deepwater Horizon oil spill
Author(s): C M Jelsema, S D Peddada

NIEHS

EPIG-3

Analgesic use and risk of renal cell carcinoma in two US populations
Author(s): S Karami, SE Daughtery, K Schwartz, FG Davis, JJ Ruterbusch, S Wacholder, BI Graubard, MP Purdue, LE Moore, JS Colt

NCI

EPIG-4

Sex and Age-Specific Associations between Gait Efficiency and Daily Activity
Author(s): DC Kauffman, E Simonsick, SA Studenski

NIA

EPIG-5

Coal for cooking and all-cause and cause-specific mortality in a prospective study of women in Shanghai, China
Author(s): C Kim, XO Shu, HD Hosgood, BA Bassig, YB Xiang, WJ Seow, HL Li, BT Ji, W Hu, C Wen, WH Chow, G Yang, YT Gao, W Zheng, N Rothman, Q Lan

NCI

EPIG-6

A novel statistical tool for regression analysis of a skewed biomarker subject to pooling
Author(s): EM Mitchell, RH Lyles, M Danaher, AK Manatunga, EF Schisterman

NICHD

EPIG-7

Comparison of NHANES 2007-2010 methodologies for assessing dietary supplement use
Author(s): HL Nicastro, RL Bailey, KW Dodd

NCI

EPIG-8

Estimating additive interactions from first principles
Author(s): OA Panagiotou, S Wacholder

NCI

EPIG-9

Updated analysis of pregnancy outcomes in the Costa Rica Vaccine Trial (CVT) and the long-term follow-up
Author(s): OA Panagiotou, B Befano, P Gonzalez, C Porras, AC Rodriguez, R Herrero, M Schiffman, AR Kreimer, A Hildesheim, A Wilcox

NCI

EPIG-10

No gender differences in the frequency of common single nucleotide polymorphisms associated with age-related macular degeneration in two independent cohorts
Author(s): NA Popp, J Tuo, EY Chew, CC Chan

NEI

EPIG-11

Oral leukoplakia and oral cavity cancer risk among elderly adults in the United States 2002-2009
Author(s): EL Yanik, EA Engels, HA Katki, AK Chaturvedi

NCI

EPIG-12

Association of Anti-Mullerian Hormone(AMH)and recurrent pregnancy loss
Author(s): SM Zarek, EF Schisterman, EM Mitchell, RM Silver, J,H, Segars, SL Mumford

NICHD

EPIG-13

Differential miRNA expression influenced by race in hypertensive and non-hypertensive women
Author(s): DF Dluzen, N Noren Hooten, Y Zhang, KD Jacob, AB Zonderman, MK Evans

NIA

HEALTH-1

Health disparities and gastrointestinal symptoms in individuals living with the human immunodeficiency virus (LWHIV)
Author(s): B Rahim-Williams, JA Erlen, KA Kim, LB Sherwin, SK Abey, NH Fourie, WA Henderson

NCMHD

HEALTH-2

Activated mast cells produce soluble ST2-a decoy receptor for IL-33
Author(s): G Bandara, MA Beaven, A Olivera, AM Gilfillan, DD Metcalfe

NIAID

IMMUNO-1

Rescue of Vaccine T cell Memory Following Sublethal Gamma Irradiation
Author(s): JD Berkson, HI McFarland, J Lee, A Elkahloun, AS Rosenberg

FDA/CBER

IMMUNO-2

Age-related macular degeneration among uveitis patients
Author(s): AR Fox, CA Cukras, NP Bhatt, WR Tucker, EY Chew, RB Nussenblatt, HN Sen

NEI

IMMUNO-3

Altered Inactivation of commensal LPS due to acyloxyacyl hydrolase deficiency in colonic dendritic cells impairs mucosal Th17 immunity
Author(s): BM Janelsins, M Lu, SK Datta

NIAID

IMMUNO-4

The capture and quantitation of cytokines in clinical samples
Author(s): HR Kalish

NIBIB

IMMUNO-5

Inducible T cell kinase regulates CD8+ T lymphocyte effector function
Author(s): SM Kapnick, PL Schwartzberg

NHGRI

IMMUNO-6

Constitutively activated KIT in mastocytosis patients is associated with decreased levels of the scavenger protein DJ1 and concomitant increases in reactive oxygen species
Author(s): DK Kim, MA Beaven, G Cruse, C Prussin, H Komarov, M Carter, DD Metcalfe, A Olivera

NIAID

IMMUNO-7

Pathogenicity of autoreactive Th17 cells is dependent on T-bet expression in non-T-helper cells in experimental autoimmune encephalomyelitis
Author(s): B Kwong, D McGavern, V Lazarevic

NCI

IMMUNO-8

Analysis of Protein O-fucosyltransferase 1 regulation of Toll-like receptor signaling in macrophages
Author(s): J M Mann, N Li, K Laky, IDC Fraser, A Nita-Lazar

NIAID

IMMUNO-9

Bortezomib reduces preexisting antibodies to recombinant immunotoxins in mice
Author(s): ML Manning, E Mason-Osann, M Onda, I Pastan

NCI

IMMUNO-10

Development of a new immunotoxin with low immunogenicity for Mesothelin expressing cancers by diminishing B and T cell epitopes
Author(s): R Mazor, D Park, R Beers, I Pastan

NCI

IMMUNO-11

Reverse immune surveillance and IL21: lessons from SJL mice and human angioimmunoblastic T cell lymphoma
Author(s): HC Morse, S Jain, J Chen, A Nicolae, H Wang, D Shin, EA Adkins, TJ Sproule, T Sakai, AL Kovalchuk, M Raffeld, JM Ward, TA Waldmann, ES Jaffe, DC Roopenian

NIAID

IMMUNO-12

STAT3 plays a critical role in histamine-induced vascular permeability
Author(s): M O'Connell, V Hox, A Olivera, D Metcalfe, J Milner

NIAID

IMMUNO-13

Increased gc receptor expression does not augment but paradoxically inhibits gc cytokine signaling and ameliorates lethal autoinflammatory disease
Author(s): J Park, AT Waickman, C Hong, H Park

NCI

IMMUNO-14

Antioxidant Treatment Rescues Hematopoietic Phenotypes in Different Models of Adenylate Kinase 2 Deficiency
Author(s): Alber Rissone, Katja Weinacht, Kevin Bishop, Jaya Jagadeesh, Maryp Jones, Setta Chandrasekharappa, Raman Sood, Luigi Notarangelo, Fabio Candotti

NHGRI

IMMUNO-15

Phosphoproteome profiling of toll-like receptor response to different ligand stimulation in macrophages identifies differentially activated pathways and phosphorylation kinetics
Author(s): V Sjoelund, M Smelkinson, A Nita-Lazar

NIAID

IMMUNO-16

Secretion of Polyreactive Antibodies is Profoundly Influenced by the Stimulation of Toll-Like Receptors (TLR)
Author(s): G Sreenivasulu, RJ Messer, C Xu, KJ Hasenkrug, WG Jr Coleman, AL Notkins

NIDCR

IMMUNO-17

Identification of a suppressor of autoimmune disease that affects deoxynucleotide synthesis in T cells
Author(s): T Tarasenko, W Zheng, B Scott, S Bolland

NIAID

IMMUNO-18

A Novel Ghrelin Receptor Antagonist May Serve as a Therapeutic Target for Alcoholism: From Bench to Bedside, a Complete Translational Study
Author(s): AH Pilling, JD Tapocik, A Pincus, C Frable, F Akhlaghi, M Heilig, L Leggio

NIAAA

PHARM-1

Interactive effects of tolcapone and catechol-o-methyltransferase (COMT) on anxiety in healthy volunteers
Author(s): DN Pratt, ND Fogleman, KF Berman, DD Dickinson, JA Apud

NIMH

PHARM-2

A systems approach identifies cooperative targeting of MYC by combined mTOR/HDAC inhibition for cancer treatment
Author(s): JK Simmons, AM Michalowski, BJ Gamache, W DuBois, JM Gary, J Patel, K Zhang, S Zhang, J Huang, BA Mock

NCI

PHARM-3

The role of WNT singling activation and its blockage in the focal retinal lesion of Ccl2-/-/Cx3cr1-/- mice with and without rd8 background
Author(s): J Tuo, Y Wang, R Chen, Y Li, M mei, H Qian, D Shen, R Pelnalva, M Abu-Asab, H Xu, J Ma, CC Chan

NEI

PHARM-4

Location matters: functional analysis of monoclonal antibodies to various regions in glypican-3
Author(s): YF Zhang, M Feng, Z Tang, M Ho

NCI

PHARM-5

Quantitative profiling of environmental chemicals and drugs for farnesoid X receptor activity
Author(s): CW Hsu, J Zhao, R Huang, JH Hsieh, JT Hamm, X Chang, KA Houck, M Xia

NCATS

SYSBIO-1

Automated image analysis for quantifying individual transcript molecules inside morphologically-diverse macrophage cells
Author(s): WW Lau, A Martins, M Narayanan, JS Tsang

CIT

SYSBIO-2

Simulation of the macrophage chemotaxis pathway facilitated by targeted proteomics
Author(s): NP Manes, M Koppenol-Raab, E An, VH Sjoelund, J Sun, BR Angermann, M Ishii, M Meier-Schellersheim, RN Germain, A Nita-Lazar

NIAID

SYSBIO-3

Identification of a virion-associated B cell entry determinant for Kaposi’s sarcoma associated herpes virus
Author(s): S J Dollery, R J Santiago-Crespo, D Chatterjee, E A Berger

NIAID

VIROL-1

Mapping of an H5N1 influenza MAb epitope on hemagglutinin and the conformational dependence of binding
Author(s): JR Gallagher, AK Harris

NIAID

VIROL-2

Developing soluble co-receptor mimetics for the study of HIV Env/receptor interactions
Author(s): A Hajduczki, VG Bundoc, JE Seedorff, EA Berger

NIAID

VIROL-3

In vitro anti-influenza A activity of interferon (IFN)-λ1 combined with IFN-β or oseltamivir carboxylate
Author(s): NA Ilyushina, RP Donnelly

FDA/CBER

VIROL-4

Ebola virus VP35 phosphorylation and its role in the viral lifecycle
Author(s): MR Kumar, L Diaz, S Altmann, B Ork, J Kindrachuk, RF Johnson, PB Jahrling

NIAID

VIROL-5

Functional genomic screen for identification and characterization of host factors required for retrovirus-like element Tf1 integration in Schizosaccharomyces pombe genome
Author(s): Henry Levin

NICHD

VIROL-6

Characterization of Antibody Interactions to Influenza Hemagglutinin
Author(s): DM McCraw, AK Harris

NIAID

VIROL-7

Evaluation of Murine Immune Responses to Improved Bivalent Vaccines against Rabies Virus and Ebola Viruses
Author(s): AB Papaneri, M Willet, C Wirblich, RF Johnson, MJ Schnell, PB Jahrling

NIAID

VIROL-8

Characterization of novel mutations in the HIV-1 Env glycoprotein that enhance cell-to-cell viral transfer
Author(s): R Van Duyne, L Kuo, K Fujii, EO Freed

NCI

VIROL-9

GRL-0519, a novel HIV-1 protease inhibitor, has potent activity against a highly darunavir-resistant strain of HIV-1
Author(s): R S Yedidi, K Maeda, V R Kalapala, D A Davis, D Das, A K Ghosh, H Mitsuya

NCI

VIROL-10

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Poster Session IV
Wednesday, September 24, 2014 — 10:00 a.m. –12:00 p.m. — FAES Academic Center

Inhibition of collagen receptor discoidin domain receptor-1 (DDR1) tyrosine kinase enhances cytotoxicity of anti-mesothelin immunotoxin for cancer therapy
Author(s): F Ali-Rahmani, D Fitzgerald, S Martin, P Patel, C Thomas, I Pastan

NCI

CANCER-1

Migration of Bone Marrow Cells Visualized by SPECT and PET
Author(s): KO Asiedu, G Griffith, PL Choyke, N Sato

NCI

CANCER-2

C/EBPdelta Links Hypoxia And Inflammation To The Promotion Of Cancer Stem Cell Characteristics And Is a Target For HDAC Inhibitors
Author(s): B Balamurugan Kuppusamy, G Glenn Summers, S Sharan, E Sterneck

NCI

CANCER-3

MicroRNA levels in the peripheral blood of myeloma, smoldering myeloma, and MGUS
Author(s): EA Barber, W Wang, M Corrigan-Cummins, L Saleh, R Kurlander, O Landgren, KR Calvo

CC

CANCER-4

Identification of a Pro-and Anti-apoptotic controlling sequence in Human Prostate-distributed DHT-metabolizing UGT-2B15 and UGT-2B17 respectively
Author(s): NK BASU, M Basu, IS Owens

NICHD

CANCER-5

Powering proteomic research with automated capillary immunoassays - quantitative profiling of signaling pathways in limited samples with precision and accuracy
Author(s): J-Q Chen, MA Herrmann

NCI

CANCER-6

HTS of IDH1 R132H leads to identification of a potent inhibitor of IDH1 R132H capable of reducing 2-hydroxyglutarate production in U87-MG glioblastoma cells
Author(s): MI Davis, R Pragani, S Gross, J Popovici-Muller, K Straley, W Lea, Z Li, L Dang, M Shen, MB Boxer, A Simeonov

NCATS

CANCER-7

Glowing Head Mice: A Genetic Tool Enabling Reliable Preclinical Image‐Based Evaluation of Cancers in Immunocompetent Mice
Author(s): CP Day, J Carter, ZW Ohler, C Bonomi, R El Meskini, P Martin, C Graff-Cherry, L Feigenbaum, T Tüting, T Van Dyke, M Hollingshead, G Merlino

NCI

CANCER-8

PARP1 is a novel genetic interactor of BRCA2
Author(s): Xia Ding, Shyam Sharan

NCI

CANCER-9

PET Imaging of Tenascin-C with a ssDNA Aptamer
Author(s): O Jacobson, X Yan, N Gang, Y Ma, LP Szajek, DO Kiesewetter, X Chen

NIBIB

CANCER-10

The National Cancer Institute's Office of Cancer Genomics – Advancing Precision Medicine through Cutting-Edge Cancer Genomics and Functional Biology Research
Author(s): S Jagu, JN Mazerik, SL Behrman, JM Guidry Auvil, NB Griner, M Ferguson, T Calder, DS Gerhard

NCI

CANCER-11

Mass spectrometry studies of Wip1 phosphatase complex formation and post-translational modification
Author(s): LM Jenkins, SJ Mazur, E Appella

NCI

CANCER-12

The novel interactions between microRNA expression, intercellular signaling and bone differentiation in osteosarcoma
Author(s): Y Jiang, Y Gindin, P Prancis, SY Moon, S Bilke, S Davis, OD, Abaan, RL Walker, M Pineda, XL Li, M Subramanian, YJ Zhu, J Knight, J Turner, A Lal, P Meltzer

NCI

CANCER-13

CDCA7L functions as a male-specific oncogene in astrocytoma
Author(s): MH Lee, KM Reilly

NCI

CANCER-14

C/EBPdelta is a candidate tumor suppressor whose protein expression is induced by the estrogen receptor
Author(s): D Mendoza-Villanueva, S Kim, H Raza Ali, S Sharan, T Sarkar, C Caldas, G Landberg, E Sterneck

NCI

CANCER-15

Inhibitory effect of LiCl treatment on pancreatic islet β-cell tumorigenesis in the mouse model of multiple endocrine neoplasia type 1
Author(s): VI Parekh, SS Desai, SD Modali, SK Agarwal

NIDDK

CANCER-18

Hyperpolarized 13C-pyruvate magnetic resonance imaging of prostate cancer tumor xenografts
Author(s): BT Scroggins, M Matsuo, AO White, S Matsumoto, JB Mitchell, MC Krishna, DE Citrin

NCI

CANCER-20

The DNA damage response gene SLFN11 is a transcriptional target of ETS transcription factors in Ewing’s sarcoma and other cancers
Author(s): SW Tang, S Bilke, L Cao, FG Sousa, M Yamade, J Murai, V Rajapakse, LJ Helmam, PS Melzer, Y Pommier

NCI

CANCER-21

BRCA2∆105 (deletion of exons 4-7) splice variant of the Fanconi Anemia (FA) related BRCA2 IVS7+2T>G mutation – effect on bone marrow compartment of BRCA2∆105 knock-in mouse, and cell cycle response to IR induced DNA damage in vitro
Author(s): E Thirthagiri, KD Klarmann, JR Keller, SK Sharan

NCI

CANCER-22

Identification of a potential chemotherapeutic agent to treat lynch syndrome tumors
Author(s): Y Zhang, J Fox, G Elliot, G Rai, S Sakamuru, R Huang, M Xia, J Ortega, H Park, D Maloney, G Li, K Myung

NHGRI

CANCER-23

Glycolytic Remodeling Enzyme PCK2 Regulates Tumor Initiation of Prostate Cancer Cells
Author(s): JS Zhao, SX Hou

NCI

CANCER-24

KRAS and thyroid hormone receptor β mutants induce undifferentiated thyroid cancer in mice via MYC upregulation
Author(s): X Zhu

NCI

CANCER-25

Dynamic palmitoylation of H+-transporting V-ATPase subunit a1 regulates lysosomal acidification and is disrupted in Ppt1-/- mice
Author(s): MB Bagh, G Chandra, Z Zhang, S Peng, AB Mukherjee

NICHD

CELLBIO-1

Nonmuscle Myosin II Isoforms Coassemble in Living Cells
Author(s): J R Beach, L Shao, K Remmert, D Li, E Betzig, J A Hammer 3rd

NHLBI

CELLBIO-2

Screening for radiation protectors using small intestinal organoids
Author(s): S I Chung, DE Citrin

NCI

CELLBIO-3

Endotoxin Contamination of Apolipoprotein A1: Effect on Macrophage Proliferation – A Cautionary Tale
Author(s): XT Jin, Q Xu, K Champion, HS Kruth

NHLBI

CELLBIO-4

Characterization of Endocytosis in T cells
Author(s): DL Johnson, JM Wilson, JG Donaldson

NHLBI

CELLBIO-5

NF-kB in cellular senescence
Author(s): Jaimy Joy, Ranja Sen

NIA

CELLBIO-6

Integration of Glycomics, Genomics and Cell Biology in a study of Joubert Syndrome with OFD1 mutation
Author(s): MS Kane, M Davids, C Adams, M He, DA Doherty, WA Gahl, CF Boerkoel

NHGRI

CELLBIO-7

Transcriptional regulation of lysosomal and autophagosomal biogenesis in muscle cells: implications for Pompe disease
Author(s): L Li, G Gutierrez-Cruz, H Zare, N Raben

NIAMS

CELLBIO-8

Exosome secretion as an effective mechanism of LTB4 mediated signal relay in migrating neutrophils
Author(s): R Majumdar, AT Tameh, PW Kriebel, CA Parent

NCI

CELLBIO-9

The role of lysososmal biogenesis and the microphthalmia family of transcription factors in Parkin-mediated mitophagy
Author(s): CL Nezich, A Fogel, C Wang, RJ Youle

NINDS

CELLBIO-10

Molecular regulatory mechanism and function of mitochondrial lncRNAs
Author(s): JH Noh, M Gorospe

NIA

CELLBIO-11

Functional distinctions of yeast Hsp40 (J-protein) chaperones in thermotolerance, prion propagation and prion elimination
Author(s): M REidy, R Sharma, S Shastry, B-L Roberts, I Albino-Flores, S Wickner, DC Masison

NIDDK

CELLBIO-12

Analysis of micronuclei during C.elegans gametogenesis and embryogenesis
Author(s): S Rosu, O Cohen-Fix

NIDDK

CELLBIO-13

Cell Fusion Stage in Osteoclast Formation
Author(s): SK Verma, E Leikina, K Melikov, LV Chernomordik

NICHD

CELLBIO-14

Dual-targeting peripheral CB1 receptors (CB1R) and iNOS by novel hybrid compound improves anti-fibrotic efficacy and safety in liver fibrosis
Author(s): R Cinar, M Iyer, Z Liu, Z Cao, T Jourdan, G Szanda, G Godlewski, J Liu, P Pacher, K Rice, G Kunos

NIAAA

CHEMBIO-1

Discovery of a near-IR photorelease technique for targeted drug delivery
Author(s): AP Gorka, RR Nani, MJ Schnermann

NCI

CHEMBIO-2

N- to O- Rearrangement of Cyanines: Synthesis of a Robust Near-IR Fluorophore
Author(s): R R Nani, J B Shaum, A P Gorka, M J Schnermann

NCI

CHEMBIO-3

New antimalarial agents and drug targets identified from a screen against plasmodium falciparum gametocytes
Author(s): W Sun, TQ Tanaka, CT Magle, W Huang, N Southall, R Huang, SJ Dehdashti, JC McKew, KC Williamson, W Zheng

NCATS

CHEMBIO-4

MOLE-BLAST a new tool to search and classify multiple sequences
Author(s): G M Boratyn, T L Madden, S Federhen, C Schoch

NLM

COMPBIO-1

BLAST on the Cloud
Author(s): CE Camacho, M Lesko, C Cope, TL Madden

NLM

COMPBIO-2

An efficient computational method for prediction of protein binding modes in multiprotein systems
Author(s): A Cardone, SA Hassan, M Brady, RD Sriram, HC Pant

NINDS

COMPBIO-3

Bioinformatics Resource Discovery by Social Media Scanning
Author(s): T Chatterjee, L Young, M Bhagwat

OD

COMPBIO-4

Escherichia coli sigma38 promoters use two UP elements instead of a -35
Author(s): KS Franco, CNL Cagliero, YN Zhou, DJ Jin, TD Schneider

NCI

COMPBIO-5

Octopus Explorer: Visualizing GEO-based ChIP-seq data on mobile devices enables their exploration
Author(s): K Kang, L Hennighausen

NIDDK

COMPBIO-6

Identifying Bacterial Pathogens and Viruses in the Human Intestinal Tract
Author(s): DM Kristensen, EV Koonin

NLM

COMPBIO-7

GeIST: a command-line pipeline for DNA integration mapping
Author(s): MC LaFave, GK Varshney, TG Wolfsberg, AD Baxevanis, SM Burgess

NHGRI

COMPBIO-8

SigSeeker: An Ensemble for Analysis of ChIPSeq, MethylSeq and HistoneSeq data
Author(s): J Lichtenberg, EF Heuston, DM Bodine

NHGRI

COMPBIO-9

Surveying the NIH Biomedical Informatics and Computational Biology (BICB) Portfolio through Supervised Machine Learning
Author(s): PM Lyster, KA Smith, WW Lau, CA Johnson

NIGMS

COMPBIO-10

A pipeline for viral population analysis using the Primer ID method
Author(s): AJ Oler, WL Ince, JR Bennink, JW Yewdell, DE Hurt

NIAID

COMPBIO-11

Teaching EHRs to understand natural language questions about patients
Author(s): K Roberts, D Demner-Fushman

NLM

COMPBIO-12

A New 2.5D Representation for Lymph Node Detection using Random Sets of Deep Convolutional Neural Network Observations
Author(s): HR Roth, L Lu, A Seff, KM Cherry, J Hoffman, S Wang, J Liu, E Turkbey, RM Summers

CC

COMPBIO-13

Text Mining Summary Statements for Evidence of Innovation
Author(s): DE Russ, CA Johnson, L Roberts

CIT

COMPBIO-14

Model-based analysis for DNA hydroxymethylation
Author(s): K Shen, D Hurt

NIAID

COMPBIO-15

GSVseq - Detection Genomic Structural Variation Using Multi-features of Next Generation Sequencing
Author(s): Kai Ying, ZD Wang, Nancy Hansen, Jim Mullikin

NHGRI

COMPBIO-16

Granulibacter spp. isolates obtained from different chronic granulomatous disease patients are heterogeneous in responses to innate immune defenses
Author(s): J Chu, AM Pettinato, SM Holland, KA Zarember, JI Gallin

NIAID

MICROBIO-1

Title: Drug repurposing screen to identify new therapeutics for the Carbapenem-resistant Klebsiella pneumonia
Author(s): S Dai, W Sun, R A Weingarten, P Shinn, J C McKew, K M Frank, W Zheng

NCATS

MICROBIO-2

Differences in the Oral Mucosa-Adherent Microbiome in Persons with Irritable Bowel Syndrome and Healthy Controls
Author(s): NH Fourie, D Wang, PA Smyser, SK Abey, LB Sherwin, B Rahim-Williams, WA Henderson

NINR

MICROBIO-3

Exploitation of the host cell lipidation machinery by the Legionella pneumophilla U-box E3 ligase GobX
Author(s): Y Lin, TR Evans, MP Machner

NICHD

MICROBIO-4

ABC-BAC : A bacterial ATP-binding cassette importers database and classification system
Author(s): D Liou, V Nagarajan, L Xiong, D Hurt, H Pinkett, Y Huyen

NIAID

MICROBIO-5

Analysis of Composition of Microbiomes (ANCOM): A novel method for studying microbial composition
Author(s): S Mandal, W van Treuren, RA White, M Eggesbo, R Knight, SD Peddada

NIEHS

MICROBIO-6

The Escherichia coli Hsp90 homolog plays a role during bacterial cell division
Author(s): M Markovski, S Wickner

NCI

MICROBIO-7

Insights into the molecular mechanisms of immune priming in An. gambiae mosquitoes
Author(s): JL Ramirez, G de Almeida Oliveira, E Calvo, AB Barletta Ferreira, CN Serhan, JM Ribeiro, C Barillas-Mury

NIAID

MICROBIO-8

Genetic and immunologic analysis of experimental interspecies hybrids between visceral and cutaneous strains of Leishmania
Author(s): A Romano, E Inbar, A Debrabant, M Charmoy, P Lawyer, F Ribeiro-Gomes, M Barhoumi, M Grigg, J Shaik, D Dobson, S Beverley, D Sacks

NIAID

MICROBIO-9

CBFβ and RUNX1 are required at two different steps during the development of hematopoietic stem cells in zebrafish
Author(s): E Bresciani, B Carrington, S Wincovitch, MP Jones, AV Gore, BM Weinstein, R Sood, PP Liu

NHGRI

STEMCELL-1

Evaluation of drug efficacy in a cell based Niemann Pick type C disease model using cells derived from patient iPS cells
Author(s): Y Long, R Li, M Wang, S Dai, M Swaroop, JC McKew, W Zheng

NCATS

STEMCELL-2

Dynamics of histone modifications at the cytokine-inducible promoters for IDO1 and TSG-6 in human bone-marrow derived MSCs
Author(s): PJ Lynch, YI Rovira Gonzalez, HA Hursh

FDA/CBER

STEMCELL-3

Detection of genetic alteration events caused by ionizing radiation in human embryonic stem cells using next-generation sequencing
Author(s): VT Nguyen, IV Panyutin, IG Panyutin, RD Neumann

CC

STEMCELL-4

The putative tumor suppressor Madm (Mlf1-adaptor molecule) regulates stem cell competition in Drosophila adult testis
Author(s): SR Singh, Y Liu, SX Hou

NCI

STEMCELL-5

Comparative analysis of whole genome gene expression changes in cultured human embryonic stem cells in response to low, clinical diagnostic relevant, and high doses of ionizing radiation exposures
Author(s): MV Sokolov, V Nguyen, RD Neumann

CC

STEMCELL-6

Identification of novel small molecule CXCR4 inhibitors as anti-HIV agents
Author(s): D Das, K Maeda, Y Hayashi, N Gavande, D V Desai, SB Chang, AK Ghosh, H Mitsuya

NCI

STRUCTBIO-1

Exploring alternative domain architectures as a way to improve annotation consistency within the Conserved Domain Database (CDD)
Author(s): MK Derbyshire, NR Gonzales, S Lu, J He, Z Wang, SH Bryant, A Marchler-Bauer

NLM

STRUCTBIO-2

Annotation of structural motifs in the Conserved Domain Database (CDD)
Author(s): NR Gonzales, F Chitsaz, MK Derbyshire, M Gwadz, F Lu, GH Marchler, JS Song, N Thanki, J Wang, RA Yamashita, C Zheng, SH Bryant, A Marchler-Bauer

NLM

STRUCTBIO-3

A novel ubiquitin-binding domain in myosin VI with specificity for Lys63 linked ubiquitin chains
Author(s): F He, H Wollscheild, A Ehlinger, S Polo, KJ Walters

NCI

STRUCTBIO-4

The NIH 3D Print Exchange: Web-based, automated generation of biomedical 3D structure files
Author(s): D Hurt, A Vsevelod, M Coakley, M Mtingwa, M Gizaw, A Yun, E Fincher, J Swan, D Chen, N Weber, C Sastry, T Yoo, J Croghan, Y Huyen

NIAID

STRUCTBIO-5

Cryo-electron microscopy at atomic resolution
Author(s): D Matthies, A Bartesaghi, S Banerjee, A Merk, S Subramaniam

NCI

STRUCTBIO-6

The 2-start helical assembly of dynamin dictates the organization of the plasma membrane fission machinery
Author(s): AC Sundborger, S Fang, JE Heymann, P Ray, JS Chappie, JE Hinshaw

NIDDK

STRUCTBIO-7

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