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MOLE-BLAST a new tool to search and classify multiple sequences

Wednesday, September 24, 2014 — Poster Session IV

10:00 a.m. –12:00 p.m.

FAES Academic Center

NLM

COMPBIO-1

Authors

  • G. M. Boratyn
  • T. L. Madden
  • S. Federhen
  • C. Schoch

Abstract

MOLE-BLAST is a new tool to classify multiple query sequences and discover their relationship to each other. This tool provides a taxonomic context for the queries. First, MOLE-BLAST groups the query sequences by locus. Second, it performs a BLAST database search to identify each query's nearest neighbors. Third, it computes a multiple alignment for each locus, including query sequences and their nearest neighbors. Finally, MOLE-BLAST presents the result of its analysis as phylogenetic tree for each locus.

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