New biological targets for drug discovery/development

Monday, September 22, 2014 — Concurrent Symposia Session I
2:00 p.m. – 4:00 p.m.	Lipsett Auditorium

Chair

• John Williamson, NCCAM

Program

Target identification plays a crucial role in drug discovery. Over the years biological and technological advances have resulted in the increasing use of assays to discover new biologically active small molecules. Target identification can be approached by a variety of mechanisms including direct biochemical methods, genetic interactions, computational inferences, as well as combinations of approaches. This symposium has been designed to evoke thought into the use and potential of several New Drug Targets.

Anti-infectives from nature
Carole Bewley, NIDDK

Designing glycopeptides as oligomannoside mimics
Sabrina Lusvarghi, NIDDK

Targeting protein sumoylation with natural products
Jay Schneekloth, NCI

Mice, snakes, and somatosensation: How natural products and genetics help us to understand pain
Alex Chesler, NCCAM

Leveraging the NF-kappaB pathway in ovarian cancer
Christina Annunziata, NCI

Designing glycopeptides as oligomannoside mimics: Exploring the structural basis of glycan recognition by the potent antiviral lectin griffithsin; FARE Award winner
Sabrina Lusvarghi, NIDDK

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