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Simple microfabrication techniques for biomedical applications

Wednesday, October 26, 2011 — Poster Session III

10:00 a.m. – Noon

Natcher Conference Center

NIBIB

TECH-6

Authors

  • N Morgan
  • J Romantseva
  • J Yoon
  • M Chandrangsu

Abstract

Microfabricated structures have been used in a wide variety of biomedical applications over recent years, from cell confinement in simple well structures to lab-on-a-chip microfluidic devices for molecular analysis. Our group has developed an on-campus facility for microdevice fabrication, enabling us to pattern features using optical lithography with resolution down to ten microns with rapid turnaround. This poster will provide an overview of capabilities and techniques for microfluidic device and microstructure fabrication in glass, plastic, polydimethylsiloxane (PDMS), and hydrogels. It will also discuss options available to intramural researchers interested in designing, making, or using microfabricated or microfluidic devices. Examples of ongoing collaborations include microwells for trapping and positioning cells, gradient formation for measurements of chemotaxis in 3D culture, immunoassay miniaturization, and fabrication of gratings for phase-contrast X-ray imaging.

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