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Patient-Reported Outcomes Measurement Information System® (PROMIS): the science of patient-reported outcomes

Wednesday, October 26, 2011 — Poster Session III

10:00 a.m. – Noon

Natcher Conference Center




  • P Tonkins
  • S Wearins
  • J Witter
  • S Serrate-Sztein


The Patient-Reported Outcomes Measurement Information System® (PROMIS) demonstrates a cooperative collaboration between the federal government and academic institutions to improve public health through innovative and effective information technology and informatics applications. As a National Institutes of Health (NIH) Roadmap initiative, PROMIS® is an innovative tool assessing health outcomes from the patient perspective. PROMIS® combines the use of Item Response Theory (IRT) and Computer Adaptive Testing (CAT) to administer a flexible, automated tool measuring health outcomes. PROMIS® objectives are to: 1) develop, test, and validate large banks of items measuring patient-reported outcomes, 2) create a computerized adaptive testing system that provides efficient, psychometrically robust assessment of clinical patient-reported outcomes in various chronic diseases, and 3) create a publicly available system that could be added to and modified periodically to allow clinical researchers access to a common repository of items and the CAT system. The PROMIS® initiative has exceeded its goals of developing PRO domains and making them available as short forms and CAT through the web-based PROMIS® Assessment Center ( The PROMIS® consists of 15 domains measuring global health, physical function, fatigue, pain, emotional distress, and social health. PROMIS® has expanded domains to include Pediatrics, Women, Minorities, and Persons with disabilities.

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