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Quantification of accuracy and precision of cardiac magnetic resonance T1 mapping: a phantom study

Wednesday, October 26, 2011 — Poster Session III

10:00 a.m. – Noon

Natcher Conference Center




  • K Nadine
  • J Lee
  • C Sibley
  • M Nacif
  • N Gai
  • P Kellman
  • D Bluemke


Purpose: Myocardium T1 mapping is a promising technique for noninvasive quantification of diffuse myocardial fibrosis. The purpose of this study is to determine whether and to what degree absolute T1 values vary between different imagers, vendors, and intra-imager condition using modified look-locker with inversion recovery (MOLLI) sequence. Materials and Methods: Multiple MOLLI scans of an identical phantom were acquired using different MRI imagers provided by two vendors at both 1.5T and 3.0T. Similar acquisition parameters were maintained across the experiment. Results: There is little inter-scanner variation within the same vendor and substantial inter-vendor variation. Conclusion: There is significant variability in T1 values depending on the imagers, vendors and field strength. The relative extracellular volume fraction may be more suitable than T1 values for evaluating myocardial diffuse fibrosis.

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