Functional near infrared spectroscopy with anatomical registration

Wednesday, October 26, 2011 — Poster Session III
10:00 a.m. – Noon	Natcher Conference Center	NICHD	IMAG-2

Authors

• F Amyot
• TR Zimmermann
• J Riley
• JM Kainerstorfer
• V Chernomordik
• L Najafizadeh
• F Krueger
• E Wassermann
• AH Gandjbakhche

Abstract

Functional near infrared spectroscopy (fNIRS) is a reliable technique for noninvasive measurement of local changes in hemodynamic in areas of the brain near the head surface. It is an alternative of fMRI but it is limited with the absence of registration with anatomical data. The combination of fNIRS device and stereotactic camera allow us to register the functional image issued with fNIRS and any anatomical image previously acquired. Image reconstruction of level of oxyhemoglobin and deoxyhemoglobin is made by combining data from multiple subjects. With fNIRS, we reinvestigating the patterns of brain activation while healthy volunteers were engaged in the task of evaluating the complexity (i.e. numbers of events) of daily life activities selected on the basis of normative data. Our results show activation in the medial frontopolar cortex. In the region of interest, the fNIRS image reconstructed has a spatial resolution of ~3pt/mm

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