Body mass index does not impact number of oocytes retrieved or oocyte maturation in women undergoing ART

Wednesday, October 26, 2011 — Poster Session III
10:00 a.m. – Noon	Natcher Conference Center	NICHD	ENDOC-2

Authors

• SA Beall
• G Levy
• M Maguire
• M Payson
• B Steggman
• J Segars

Abstract

Objective: To evaluate the effect of body mass index (BMI) on the number of oocytes retrieved and percentage of mature oocytes. Materials and Methods: One thousand six hundred twenty five cycles performed between January 2002 and July 2009 were reviewed retrospectively. Outcomes included: age, BMI, FSH, estradiol levels, days of stimulation, ampoules of gonadotropin, cycle type, oocytes retrieved, oocyte maturity and pregnancy. Patients were divided based on their BMI into the following groups: underweight (BMI < 18.6), normal weight (BMI 18.6-24.9), overweight (BMI 25-29.9), obese (BMI 30-39.9), morbidly obese (BMI > 40). All women underwent controlled ovarian stimulation using either luteal lupron or microdose lupron (MDF) protocols. Results: Patient characteristics did not vary between the BMI groups. There was no significant difference in the number of oocytes retrieved or the percentage of MII (mature) oocytes between the BMI groups analyzed. There was no statistical difference in the pregnancy between the BMI groups. Conclusions: In this cohort, BMI did not negatively impact the number of oocytes retrieved, rate of oocyte maturation, or pregnancy outcome of ART. Underweight and morbidy obese women were often stimulated using the MDF protocol and required a higher dose of gonadotropins, although the differences were not significant.

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