Phenotyping metabolic disease in mice

Thursday, October 27, 2011 — Core Poster Session
10:00 a.m. – Noon	South Lobby of Building 10	NIDDK	CORE-25

Authors

• W Jou
• T Chanturiya
• O Gavrilova

Abstract

Diabetes and obesity are very common in Western society. In spite of their prevalence, our understanding of their molecular basis is rudimentary. Mouse models of obesity and diabetes contribute greatly to a better understanding of how the environmental and genetic causes affect metabolism, however performing well-controlled metabolism experiments in mice is difficult due to their small size. The NIDDK Mouse Metabolism Core Laboratory provides metabolic and physiologic phenotyping services for mouse models of diabetes, obesity and related disorders. A variety of in vivo and in vitro techniques is available for measuring energy balance, glucose fluxes and other metabolic alterations in transgenic mice.

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