Racial/ethnic disparities in assisted reproductive technology (ART) outcomes: an analysis of 10,413 patients from a single fertility practice

Wednesday, October 26, 2011 — Poster Session III
10:00 a.m. – Noon	Natcher Conference Center	NICHD	CLIN/CULT/AGING/DISPREV-18

Authors

• K Moon
• K Richter
• J Segars
• E Wolff
• E Widra

Abstract

Objective: There is increasing evidence supporting racial/ethnic disparities in ART outcomes, but most studies are limited by small sample size. We analyzed differences in ART outcomes in a large fertility practice amongst Caucasian (CA), Hispanic (HI), Asian (AS), and African-American (AA) women. Materials and Methods: Patients undergoing initial autologous ART cycles from 2004-2009 were compared by racial/ethnic subgroups. Results: 10,413 cycles were analyzed (CA n=6978, HI n=431, AS n=1384, AA n=1620). AA had higher rates of tubal and uterine factor infertility. AA and AS had significantly higher estradiol levels (2270 and 2247 pg/mL) than HI and CA (2011 and 2043 pg/mL). AA and CA had a similar number of oocytes retrieved (14.2 and 14.2), but AA had significantly lower fertilization than CA (6.7 vs 7.2 2PN embryos). AA also had significantly lower pregnancy rates than CA and AS and lower live birth rates than all other groups. AA had significantly higher SAb rates at a significantly later gestational age than CA and AS. Conclusions: In this large single-site cohort, AA had lower live birth rates and a higher rate of reproductive loss at the most advanced gestational age when compared to all other subgroups (HI, CA and AS).

back to top