Biophysical methods for intramural scientists

Monday, October 24, 2011 — Poster Session I
Noon – 2:00 p.m.	Natcher Conference Center	NIBIB	BIOPHY-1

Authors

• PH Brown
• A Balbo

Abstract

Biophysical studies offer insight into how protein structure affects biological function. Unfortunately, these studies typically require purchasing and maintaining sophisticated, costly instrumentation. An additional barrier to owning these instruments is the level of expertise required to operate them and to interpret acquired data. In the Quantitative Methods for Macromolecular Interactions Unit (QMMI) of the Biomedical Engineering and Physical Science Shared Resource), NIBIB, a large variety of biophysical instrumentation is available to intramural researchers; including: analytical ultracentrifugation, isothermal titration and differential scanning calorimetry, dynamic light scattering, surface plasmon resonance biosensors, and circular dichroism spectroscopy. The resource is staffed with experts to advise in experimental design and to interpret results. The purpose of this poster is to outline the types of instrumentation available to intramural researchers within the QMMI, and to provide an overview of how the techniques work and what kind of information they can provide.

back to top