Research Festival 2002, October 15-18
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General Schedule of Events
NIH Job Fair for Postdocoral Fellows
Special Exhibits on NIH Intramural Resources
TSA Research Festival Exhibit Show
Plenary Sessions
Poster Sessions
Festival Food and Music Fair
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Mini-Symposia Session IV Thursday, October 17
Proteomics 2:00 p.m. to 3:30 p.m.
Natcher Conference Center
Main Auditorium
Chaired by Amina Woods, NIDA

The mini-symposium goals are to highlight the latest analytical advances in proteomics, and give practical examples of the role proteomics play in the study of proteins and their potential use as disease markers.

Alfred Yergey, NICHD The Role of Complete De Novo Peptide Sequencingin Protein Characterization with the MALDI Tandem TOF
Jeff Kowalak, NIMH Multidimensional LC/MS Strategies for Proteomics
Donita Garland, NEI The Lens Proteome: Development, Pathology and Down’s Syndrome
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Chipping Away at Cancer: 2:00 p.m. to 3:30 p.m.
Natcher Conference Center
Conference Room E1/E2

Applications of Gene Expression Profiling for Human Cancers and Mouse Models
Chaired by Jeffrey E. Green, NCI

The explosion of microarray data related to cancer has opened enormous opportunities to explore the genetic complexity of oncogenesis and to utilize this information to make more precise diagnoses, predictions of prognosis and to further individualize patient therapy. These themes will be explored in this symposium where microarray approaches for studying various types of human malignancies will be presented. Gene expression profiling of mouse models of human breast cancer will be discussed in terms of understanding molecular pathways of oncogenesis, model validation and integration of models into pre-clinical studies. Exciting new approaches to drug discovery are being developed using array technologies and the impact of these methods on pharmacology and clinical trials will be considered.

Lou Staudt, NCI Molecular Diagnosis and Molecular Targets in Lymphoid Malignancies
Paul Meltzer, NHGRI Using Microarrays to Study Signaling in Breast Cancer
Kartiki Desai, NCI Insights into Mouse Models of Breast Cancer Using Gene Expression Profiling and BAC Arrays
Kim Bussey, NCI Moving From Gene Expression Profiles to Pharmacology in Cancer
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Neural, Endocrine and Immune Factors in Infectious Diseases 2:00 p.m. to 3:30 p.m.
Natcher Conference Center
Balcony B
Co-chaired by Esther Sternberg, NIMH and Adriana Marques, NIAID

This mini-symposium focuses on the role of the immune system in the pathogenesis of central nervous system infections as well as the role of neural factors, neurotransmitters and neurohormones in susceptibility, course and severity of systemic infections.

Adriana Marques, NIAID The Cellular Response to B. burgdorferi
Eugene O. Major, NINDS Importance of Lymphocytes and Glial Cells in the Molecular Pathogenesis of Viral Infections in the Human Brain
Esther M. Sternberg, NIMH Neuroendocrine and Neural Factors in Peripheral Infection and Septic Shock
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