Friday, November 08, 2013 — Poster Session IV | |||
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2:00 p.m. – 4:00 p.m. |
FAES Academic Center (Upper-Level Terrace) |
NIAID |
VIROL-7 |
Characterization of Human Betacoronavirus 2c EMC/2012 Linked to Acute Respiratory Distress Syndrome in Humans Human betacoronavirus 2c EMC/2012 was isolated from a subject with acute pneumonia in June 2012. This poster will characterize the genome sequence, arrangement, and phylogenetic relation with known coronaviruses sampled from around the world including the Middle East respiratory symptom coronavirus (MERS-CoV). The genome contains 30,119 nucleotides and contains at least 10 predicted open reading frames, 9 of which are predicted to be expressed from a nested set of seven subgenomic mRNAs. Phylogenetic analysis of virulence factors of sequenced genomes indicated that HCoV-EMC/2012 is most closely related to species within the genus Betacoronavirus.