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Translating biospecimen science research results to improved biospecimen practices

Thursday, November 07, 2013 — Poster Session II

12:00 p.m. – 2:00 p.m.

FAES Academic Center (Upper-Level Terrace)




  • HM Moore
  • KB Engel
  • SR Greytak
  • BP Bass
  • J Vaught


Cancer tissues and blood are collected, processed and stored in many different ways across the world. The NCI Biospecimen Research Network (BRN) program sponsors, conducts, and collaborates on Biospecimen Science research to better understand how different biospecimen practices influence the molecular integrity of biospecimens, and in turn, how such variation affects the reproducibility of research results. Results from BRN program-sponsored research on the systematic perturbation of blood and tissue collection and processing procedures will be summarized. Meta-analyses of the Biospecimen Science literature, using the NCI Biospecimen Research Database (, are being performed in order to provide citable evidence for biospecimen best practices. We will also describe current progress on the development of Biospecimen Evidence-based Practices based on BRN research results, literature evidence, and expert input. Such analysis reveals the significant gaps in Biospecimen Science knowledge and points to the continuing need for new research in Biospecimen Science. Nevertheless, we are now poised to translate Biospecimen Science research findings to improved biospecimen practices that will benefit the large community of stakeholders that utilizes human biospecimens for research.

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