The Imaging Probe Development Center is a synthetic chemistry core facility

Wednesday, November 06, 2013 — Poster Session I
4:00 p.m. – 6:00 p.m.	FAES Academic Center (Upper-Level Terrace)	NHLBI	MOLBIO-5

Authors

F. Bhattacharyya
A. Opina
D. Sail
N. Shenoy
Z.-D. Shi
A. Sulima
H. Wu
B. Xu
V. Coble
K. Lane
C. Li
K. Lincoln
M. Cherukuri
J. Mitchell
O. Vasalatiy

Abstract

The Imaging Probe Development Center (IPDC) was founded with the goal of providing fundamental synthetic chemistry support needed to advance molecular imaging technologies for interdisciplinary NIH research community. The IPDC laboratories are located in Rockville, MD with state-of-the-art equipment and the new PET facility is scheduled to open in November 2013 at NIH main campus. The IPDC has a rolling solicitation system and NIH scientists are welcome to contact and submit a proposal with the request for synthesis of a particular probe in which they are interested. Probes can be intended for all types of imaging modalities, such as optical fluorescence, PET/SPECT and MRI. IPDC scientists can synthesize requested probes that are published in literature but commercially unavailable, or are completely novel. Examples of molecular imaging probes we have produced range from low molecular weight entities to high molecular weights conjugates and include fluorescent dyes and their analogs, lanthanide complexes, fluorogenic enzyme substrates, caged dyes which become fluorescent upon irradiation, radio and fluorescent labeled peptides, proteins and antibodies, gold and iron oxide nanoparticles, dendrimers and liposomes. For more information please visit our website: http://www.nhlbi.nih.gov/research/intramural/researchers/programs/imaging-probe-development-center/index.html