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Characterization of Autism Spectrum Disorders (ASD) using near infrared spectroscopy (NIRS) to study cognitive brain function

Thursday, November 07, 2013 — Poster Session II

12:00 p.m. – 2:00 p.m.

FAES Academic Center (Upper-Level Terrace)

NICHD

BIOENG-3

Authors

  • AA Anderson
  • V Chernomordik
  • F Amyot
  • F Chowdhry
  • AH Gandjbakhche

Abstract

Autism Spectrum Disorders (ASD) refers to group of developmental disabilities that result in difficulties in social interactions, communication behaviors, and activities. Early detection of ASD during childhood is therefore critical for therapy and early intervention treatment to manage further development. Functional near infrared spectroscopy (fNIRS) is a non-invasive imaging method that can be used to assess cognitive brain function. In this clinical study, using fNIRS, our aim is to correlate the impairment in ASD population with their brain functionality and cerebral autoregulation and to detect the biomarkers for differentiation of ASD from typical subjects. Set of functional tasks that have the potential for being used as biomarker in ASD groups are selected. For pilot study, we recruited typical and ASD children from age 5 to 7 and used fNIRS device to detect brain activation in prefrontal cortex during performance of functional task. Initial results from this study along with methodology and future directions will be presented.

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