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PET Quantification in the Presence of Attenuation Correction Errors Caused by MR Coils

Thursday, November 07, 2013 — Poster Session II

12:00 p.m. – 2:00 p.m.

FAES Academic Center (Upper-Level Terrace)




  • MA Ahlman
  • R Maass-Moreno
  • S Liu
  • DA Bluemke


MR-PET attenuation correction (AC) is problematic due to overlying MR coils, and we validate a procedure for quantitative accuracy in this setting. Cylindrical phantoms 12cm and 21cm in diameter containing 18FDG solution and a 68Ge solid mix (each 10 kBq/ml) were scanned on a PET-CT without coils (control); then with a mMR Body A-Tim, low attenuating coil (LAC); and a carotid coil (CC) of unknown attenuation. Image reconstruction used the µ-map from the control. ROIs were placed on PET artifacts (PA) and at the anatomic depth of the carotid jugular to create carotid/jugular ratios (CJ). Compared to control, average% differences(±SD) in PA were obtained for LAC and CC. Compared to the ideal ratio of 1.0, %errors in the CJ were described (mean±SD). For the Large phantom, VAD %errors in the LAC and CC compared to control were 14.0%(2.0) and 6.5%(4.9). By contrast, the CJ ratios for the LAC and CC for the large phantom compared to control were 2.6%(0.35) and 2.4%(0.75). With no significant PA for the small phantom, CJ for LAC and CC had 1.0%(0.7) and 1.1%(0.9) error. All commonly used MR-PET coils cause significant AC errors which can be corrected for by CJ.

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