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Personality and expectancy measures predict rates of intravenous (IV) alcohol self-administration in social drinkers

Friday, November 08, 2013 — Poster Session III

10:00 a.m. – 12:00 p.m.

FAES Academic Center (Upper-Level Terrace)




  • B.L. Stangl
  • M. Zametkin
  • V. Vatsalya
  • V.A. Ramchandani


Computer-Assisted Self-Infusion of Ethanol (CASE) is a method of IV alcohol administration that provides individuals with access to ad-lib self-infusions of alcohol. The objective was to examine the effects of impulsivity and expectancy on IV alcohol self-administration behavior. Social drinkers (N=102) underwent a self-administration session that consisted of a 25-minute priming phase where subjects were prompted to push a button to receive individually standardized alcohol infusions, followed by a 2-hour “open-bar” phase with ad-lib access to the same infusions. Participants were grouped based on the number of infusions they administered during the first 30 minutes of the session: non-, low, and high responders (0, 1-5, or 6-12 infusions, respectively). Results indicated significant differences between non-, low and high responders for personality and expectancy measures. High responders had lower expectancy scores for power and aggression as well as cognitive and physical impairment. High responders also had greater measures of impulsivity (all p values <0.05). Results indicate that higher rates of self-administration were associated with higher impulsivity, and lower expectancy of cognitive and physical impairment and aggression following alcohol. These findings suggest that the rate of IV alcohol self-administration is sensitive to the expected behavioral effects of alcohol in social drinkers.

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