Co-Chaired by:
Beverly Mock, NCI/CCR and Alan Kimmel, NIDDK

Natcher Conference Center - Balcony A

The target of rapamycin (TOR) is central to cell growth and nutrient sensing pathways. The ability of TOR to phosphorylate substrates such as p70S6 kinase, 4E-BP1, Akt and p53, place it as a key signaling node involved in many pathways which have the potential to modulate both developmental and disease-related processes as diverse as stem cell fate, diabetes, aging and cancer. This symposium will highlight the TOR research of NIH investigators from different institutes and disciplines.

Program:

The Antagonistic Actions of TOR Complexes 1 & 2
Alan Kimmel, NIDDK

TOR Complex 2 Integrates Chemotaxis and Signal Relay in Dictyostelium
Carole Parent, NCI/CCR

mTOR Activity Regulates Stem Cell Fate
Toren Finkel, NHLBI

The Role of mTOR in Pediatric Cancers
Lee Helman, NCI/CCR

mTOR acts as a Tumor Suppressor in Plasma Cell Tumor Development
Beverly Mock, NCI/CCR