Co-Chair:
Bruce A. Shapiro, NCI

Natcher Conference Center - Conference Room F1/F2

Understanding the relationships that exist between RNA structure and function has become a significant area of interest and importance over the last several years. This session will discuss some of the recent developments in determining and understanding these relationships both from an experimental and computational point of view. This symposium will focus on the structural and functional relationships associated with small RNAs in retroviruses and bacteria, a new approach that combines NMR and scattering methodologies for determining the structure of large RNAs, and computational developments associated with the emerging field of RNA nanobiology.

Program:

Small RNAs and Human Retroviruses --- What are We Learning?
Kuan-Teh Jeang, NIAID

Structure Requirements for Small RNA Regulation of mRNA Translation in Bacteria
Susan Gottesman, NCI

Large Pictures with Small Details: Combined use of NMR and Scattering Data for RNA Structure Determination
Yun-Xing Wang, NCI

Computational Approaches to RNA Nanodesign
Bruce A. Shapiro, NCI