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NIH Research Festival 2005
2005 NIH Research Festival

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October 18 - October 21
General Schedule of Events
Poster Sessions
Plenary Session
Concurrent Symposia
Job Fair for NIH Postdoctoral, Research, and Clinical Fellows
Special Exhibits on Resources for Intramural Research
TSA Research Festival Exhibit Show
Festival Food and Music Fair
Research Festival Committees
Past Research Festivals
Symposia Session III - 7 concurrent symposia
  Wednesday, October 19, 2005
Natcher Auditorium

The X Chromosome and Sex-based Differences in Normal and Pathophysiology

2:30 p.m. - 4:30 p.m.

David Schlessinger, NIA, Chair

Conference Room E1/E2, Natcher Conference Center

There are many important differences between men and women in normal physiology as well as disease susceptibility that may be due to differential X linked gene dosage effects. Asymmetry in X gene dosage may occur through escape from inactivation by many X linked genes that do not have Y alleles, and through genomic imprinting, since men have only Xmat while normal women have both Xmat and Xpat. The recent elucidation of X chromosome genomics should promote rapid progress in illuminating X gene dosage effects contributing to differences in physiology, cognitive function and disease susceptibility between normal men and women.


Evolution of Primate X Chromosome
James C. Mullikin, NHGRI

Escape from X Inactivation
Laura Carrel, Pennsylvania State University College of Medicine

X Chromosome Gene Dosage and the Serum Proteome
Keith Killian, NCI

X Chromosome Gene Dosage and Gender Differences in Longevity
Carolyn Bondy, NICHD

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