Co-chaired by David Segal, NCI and Felix Yarovinsky, NIAID

Balcony C, Natcher Conference Center

A decade ago, antibodies, T cells, and immunological memory, all features of the adaptive response to antigens, were considered the principal components of immunity; the phrase “innate immunity” barely registered. However, new studies on the mechanisms of the innate recognition of pathogens are rapidly revealing the extraordinary complexity and importance of innate immunity to the host defense against infectious agents. This session will focus on the most recent advances on this front by NIH and FDA scientists

Program:

Dendritic Cells as a Bridge between Innate Resistance and Adaptive Immunity
Giorgio Trinchieri, NIAID

The Molecular Structure of the Ligand-binding Domain of TLR3
Jessica Bell, NIDDK

Innate Immunity to Protozoan Parasites
Felix Yarovinsky, NIAID

Innate Immunity to Intestinal Infection with Type-1 Reovirus
Brian Kelsall, NIAID

TLR-9: Targeting the Innate Immune System for Immunoprotection
Daniela Verthelyi, DTP/CDER