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NIH Research Festival 2005
2005 NIH Research Festival

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October 18 - October 21
General Schedule of Events
Poster Sessions
Plenary Session
Concurrent Symposia
Job Fair for NIH Postdoctoral, Research, and Clinical Fellows
Special Exhibits on Resources for Intramural Research
TSA Research Festival Exhibit Show
Festival Food and Music Fair
Research Festival Committees
Past Research Festivals
Symposia Session I - 7 concurrent symposia
  Tuesday, October 18, 2005
Natcher Auditorium
B Cells in Health and Disease: From Biomarkers to Treatment Options 2:00 pm - 4:00 pm

Chaired by Peter E. Lipsky, NIAMS

Sponsored by the NIH B Cell Workshop (meets Mondays, 12:30 pm, Clinical Research Center, 4E-5121/3121)

Balcony A, Natcher Conference Center

The interdisciplinary theme is the examination of mouse and human B cell biology in relationship to B cell mediated disorders (i.e., immunodeficiency, autoimmune disease, cancer) and brings together basic as well as clinical/translational research. Presentations will highlight cutting edge techniques (i.e., proteomics and gene profiling of human B cells, confocal and video imaging of mature B cells from genetically manipulated mice,

11-parameter flow cytometry of human B cells, transfection and biochemical signaling analysis of primary human B cells and intravital microscopy of migrating mouse B cells during an immune response). Speakers are diverse, including women and minorities, and represent work in the three major disease groups affecting B cells (immunodeficiency, autoimmune disease, cancer) as well as mouse models.


B Cell Biomarkers of Autoimmune Disease: Genomic and Proteomic
Identification to Clinical Implementation
Peter E. Lipsky, NIAMS

Malignant B Cells: Gene Profiling Leads to Survival Prediction and Treatment Options
Vu Ngo, NCI

RAGs and AID: Roles in Switching and Somatic Hypermutation of Ig
Rafael Casellas, NIAMS

The Puzzle of Differentiation of Memory and Plasma Cells: Contrasting Immunodeficient and Autoimmune B Cells
Amrie C. Grammer, NIAMS

Control of B Cell Migration by RGS Proteins that Regulate Chemokine Receptor Signaling: Examination by Intravital Microscopy
John Kehrl, NIAID

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