2003 NIH Research Festival
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Mini-symposia Session I
Wednesday, October 15, 2003
Natcher Conference Center
Interconnection of Hormones, Bone and Brain 10:30 a.m. - 12:00 p.m.
Co-chaired by:
Janine A. Smith, M.D.
Deputy Clinical Director, NEI

Sponsored by the NIH Women's Health Special Interest Group
Conference Room F1/F2, Natcher Conference Center
This symposium will explore the relationships and interconnections between
hormones, depression and osteoporosis by describing the effects of sex steroid
hormones on the non-reproductive targets of bone and brain. The biology of bone
formation and maintenance of peak bone mass and the role of sex hormones in the
pathophysiology of osteoporosis will be discussed. Data suggesting that depression
is a risk factor for developing osteoporosis will be reviewed and the potential
role of sex hormones in the pathophysiology of depression will also be explored.
Results from ongoing clinical studies which characterize these relationships will
also be presented and the public health import of these disease processes illustrated.
Future directions for research and a perspective on relevant aspects of
women's health will be provided at the conclusion of the symposium.
Midlife Depression and Hormone Therapy
Peter Schmidt, M.D.
Chief, Unit on Reproductive Endocrinology, Behavioral Endocrinology Branch,
Bone Development and Maintenance of Bone Mass
Pamela Robey, Ph.D.
Chief, Craniofacial and Skeletal Diseases Branch, NIDCR
Osteoporosis and Depression
Giovanni Cizza, M.D., Ph.D.
Staff Physician, Clinical Neuroendocrinology Branch, Mood and Anxiety Disorders
Program, NIMH
What Does It All Mean and Where Do We Go from Here?
David Rubinow, M.D.
Clinical Director, Division of Intramural Research Programs, NIMH
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