2003 NIH Research Festival
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Mini-symposia Session II
Wednesday, October 15, 2003
Natcher Conference Center
Frontiers of Structural Biology: Macromolecular Complexes and Assemblies 2:00 p.m. - 3:30 p.m.
Co-chaired by:
James H. Hurley, Ph.D.
Senior Investigator, Laboratory of Molecular Biology, NIDDK
Sanford P. Markey, Ph.D.
Chief, Laboratory of Neurotoxicology, NIMH

Sponsored by the NIH Structural Biology Interest Group
Balcony C, Natcher Conference Center
The structural analysis of macromolecular complexes and assemblies is one of the
major frontiers of structural biology, and an area where NIH intramural scientists
are making important contributions. The talks represent the two most prominent
technologies for understanding these complexes, x-ray crystallography and cryo
electron microscopy. The topics will cover regulatory protein:protein and
protein:RNA complexes that are formed transiently, as well as large, stable
multiprotein assemblies.
Mechanism of Monoubiquitin Recognition from the Structure of a Targeting Domain

James H. Hurley, Ph.D.
Senior Investigator, Laboratory of Molecular Biology, NIDDK
Crystal Structure and Binding Specificity of an RNA Silencing Suppressor
Traci M. T. Hall, Ph.D.
Investigator, Laboratory of Structural Biology, DIR, NIEHS
Effects of Steric Blocking and Quasiequivalence on a Viral Antigen
Alasdair Steven, Ph.D.
Chief, Laboratory of Structural Biology Research, NIAMS
Architecture and Mechanism of an Icosahedral Pyruvate Dehydrogenase Complex
Jacqueline Milne, Ph.D.
Principal Investigator, Laboratory of Cell Biology, CCR, NCI
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