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Imaging traumatic brain injury: Challenges and solutions

Wednesday, October 10, 2012 — Concurrent Symposia Session III

2:00 p.m. – 4:00 p.m.

Conf. Room E1/E2


  • Amir H. Gandjbakhche, NICHD
  • Paul Smith, NIBIB


Approximately 1.7 million people sustain a traumatic brain injury annually. 300,000 veterans in Iraq/Afghanistan wars experienced TBI, mostly mild. Injuries range from severe structural damages detected in (MRI/CT) imaging, to those injuries which exhibit normal structural imaging but manifest different levels of cognitive deficits such as memory problems, reduced attention, inability to concentrate on a single task. The poor quality of life associated with TBI, create severe morbidities in all aspects of patient life (family, work, and society), and cost billions of dollars. Accurate diagnosis and classification of TBI are becoming a critical need for personalized therapy. However, phenotyping TBI is still a huge challenge. Imaging methods, both structural and functional, could play an important role for phenotype classification. In this symposium we will address the role of imaging techniques for TBI diagnosis and therapy.

Imaging TBI: Known knowns and unknown unknowns
James Smirniotopoulos, USUHS

Endophenotypes of traumatic brain injury: Implications for the next generation of clinical trials
Ramon Diaz-Arrastia, USUHS

The CNRM traumatic head injury neuroimaging classification (THINC) study: Steps toward the objective diagnosis and classification of TBI
Lawrence Latour, NINDS

Imaging cognitive function with near infrared spectroscopy for TBI diagnosis
Amir Gandjbakhche, NICHD

Detecting axonal degeneration in multiple sclerosis with diffusion weighted spectroscopy FARE Award Winner
Emily Wood, NINDS

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