Health disparities: Advances in translational, clinical, and population sciences

Wednesday, October 10, 2012 — Concurrent Symposia Session II
10:00 a.m. – Noon	Conf. Room F

Co-chairs

• Anil Wali, NCI
• Jeffrey Kopp, NIDDK

Program

Health Disparities are differences in health outcomes among population groups that reflect socio-economical, geographical and racial/ethnic inequalities. Biological, environmental and behavioral factors can lead to unequal disease burden in prevalence, incidence and mortality rates seen among medically underserved and vulnerable populations. This symposium is timely to take stock of implications of these factors on various disease manifestations and outcomes, and provide insights on the latest advances in combating them with high-throughput medical technologies. The symposium topic is of broad interest to NIH intramural investigators who are engaged in various aspects of trans-disciplinary efforts to understand the molecular basis of linkages between obesity, metabolomics, epigentics in population based studies. This symposium will serve as a scientific platform to exchange state-of-the-art information on racial/ethnic differences encountered in the translational setup from bench to bedside, and how these experimental approaches could improve the early detection, prevention and therapeutic strategies applicable to the communities.

Identification of APOL1 genetic variation explains much of the increased chronic kidney disease characteristic of African Americans
Cheryl Winkler, NCI

A prognostic metabolome signature in breast tumors is linked to a distinct DNA methylation pattern in African-American and European-American patients
Stefan Ambs, NCI

Molecular Linkages between race, obesity and triple-negative breast cancer
Kevin Gardner, NCI

Ethnic differences in lipid distribution: Implications for disease risk and response to treatment
Charles Rotimi, NHGRI

Health disparities in cardiovascular disease: A global health perspective
Cristina Rabadan-Diehl, NHLBI

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