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Biomedical Engineering and Physical Science

Thursday, October 11, 2012 — Poster Session III

10:00 a.m. – Noon

Natcher Conference Center, Building 45

NIBIB

TECH-3

Authors

  • HS Eden
  • PH Brown
  • EK Dimitriadis
  • AM Gorbach
  • HR Kalish
  • NY Morgan
  • GF Zhang

Abstract

The Biomedical Engineering and Physical Science (BEPS) Shared Resource develops and applies innovative technologies in support of intramural scientists throughout the NIH. Its unique expertise spans technologies ranging in scale from near-atomic resolution to intact organisms. Examples of its capabilities include: 1) biophysical methods (e.g., analytical ultracentrifugation; circular dichroism; dynamic light scattering; microcalorimetry; force spectroscopy for single molecule recognition, protein unfolding and high resolution material characterization; surface plasmon resonance sensors; and mathematical modeling), 2) imaging techniques (e.g., atomic force microscopy; transmission and scanning electron microscopy, including preparative techniques; electron tomography; and infrared/multispectral imaging of tissues and organs, including clinical imaging), 3) micro analytical chemistry (e.g., preparative immunochemical techniques, affinity and immunoaffinity analysis of sub-microliter samples; capillary electrophoresis with fluorescence detection; detection of analytes at femtogram and attogram levels; 4) microfabrication for biomedical applications (e.g., design, fabrication, and implementation of microfluidic devices, including rapid turnaround of templates down to ~2 ┬Ám dimensions; thin film fabrication, including spin coating polymers; surface modification of PDMS and other polymers, hydrogel patterning, and characterization of surfaces and devices). Please contact us for more information or to discuss potential projects: http://www.nibib.nih.gov/Research/Intramural/SharedResource

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