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Informatics Research to Support Clinical Research – the NIH Biomedical Translational Research Information System (BTRIS)

Thursday, October 11, 2012 — Poster Session IV

2:00 p.m. – 4:00 p.m.

Natcher Conference Center, Building 45




  • JJ Cimino


Clinical research today often demands data that range from genetic sequences to complete health records. The Biomedical Translational Research Information System (BTRIS) is an NIH resource that is being created to support researchers needing this range of data for their investigations. The development, though, requires solving new challenges with respect to data representation, coding, querying and analysis. Development of BTRIS itself requires research - specifically, clinical research informatics – in order better understand the information needs of researchers and the ways those needs can be met. Research topics include data modeling to integrate genetic and clinical information from current and archived resources across the 27 NIH institutes and centers, unifying the controlled terminologies that are used to code these myriad data, user interface design to anticipate and resolve the information needs of researchers, and data visualization techniques. Currently, BTRIS includes data from 23 different data sources, a clinical research ontology (the Research Entities Dictionary, or RED) with over 100,000 concepts and a user interface that provides 20 different customizable report. Data are available to NIH investigators in either identified form, for active research protocols, and de-identified form for trans-protocol queries.

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