Microfabrication and Microfluidics Unit, BEPS/NIBIB

Thursday, October 11, 2012 — NIH Core Poster Session
10:00 a.m. – Noon	Building 10 South Lobby	NIBIB	CORE-7

Authors

• N.Y. Morgan
• J. Yoon
• M. Chandrangsu
• K. Mora

Abstract

Microfabricated structures are being employed in biomedical research with increasing frequency, in applications ranging from cell-confinement in simple well structures to complex lab-on-a-chip microfluidic devices for molecular analysis. The Microfabrication and Microfluidics Unit of the Biomedical Engineering and Physical Science Shared Resource has an on-campus facility for microdevice fabrication with rapid turnaround, in which it is possible to pattern single or multilayer structures using optical lithography with resolution down to a few microns. Depending on the choice of material, these structures can be used directly for fluid confinement, or as templates for molding materials such as polydimethylsiloxane (PDMS), agarose, or other hydrogels. This poster will provide an overview of the facility capabilities, and discuss the options available to intramural researchers interested in designing, making, or using microfabricated or microfluidic devices. Some examples of current and recently completed projects include microwells for trapping and positioning cells, gradient formation for measurements of chemotaxis in 3D culture, and immunoassay miniaturization.

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