October 9 - 12, 2012
Building 10 & Natcher Conference Center
- General Schedule of Events
- Opening Plenary Session
- Concurrent Symposia Sessions
- National Graduate Student Research Conference
- FARE Award Ceremony
- Poster Sessions
- Special Exhibits on Resources for Intramural Research
- TSA Research Festival Exhibit Show
- Research Festival Committees
- Past Research Festivals
2011 program
Download the 2011 Research Festival Program Book
PDF documents require the free Adobe Reader
Genome-Wide RNAi screening at the NIH through the Trans-NIH RNAi Screening Facility
| Thursday, October 11, 2012 — NIH Core Poster Session | |||
|---|---|---|---|
10:00 a.m. – Noon |
Building 10 South Lobby |
NCATS |
CORE-6 |
Authors
- S.E. Martin
- E. Buehler
- Y. Chen
- R. Guha
- C. Klummp
- P. Tuzmen
- N.J. Caplen
- C.P. Austin
Abstract
Gene silencing through RNAi has quickly emerged as a powerful tool for genetic loss of function studies. We have established a state-of-the-art RNAi screening facility, housed at NCGC, to serve the greater NIH research community. This facility has been fully operational since 2011 and dozens of projects underway from a variety of Institutes. Studies range from identifying genes that modulate the activity of cancer drugs to those that affect virus infectivity and replication. A major part of the RNAi Facility’s mission is to advance the science of RNAi screening. Towards this end we continue to develop and improve methods that identify and interpret off-target effects in RNAi screens, which represent the major obstacle in using this technology.
