BRIDG Model – A semantic foundation for supporting interoperability in Protocol-driven Research

Wednesday, October 10, 2012 — Poster Session II
Noon – 2:00 p.m	Natcher Conference Center, Building 45	NCI	CLIN/TRANS-9

Authors

• S. Hastak
• W. Ver Hoef
• J. Evans
• R. Angeles
• L. Mckenzie
• C. Mead
• J. Speakman
• D. Patton

Abstract

The BRIDG (Biomedical Research Integrated Domain Group) Model is a collaborative effort of stakeholders from the Clinical Data Interchange Standards Consortium (CDISC), the HL7 Regulated Clinical Research Technical Committee (RCRIM TC), the National Cancer Institute (NCI), and the Food and Drug Administration (FDA) to produce a shared view of the concepts in clinical research. It provides the foundation for a common understanding of the domain of clinical trials research, thus enabling data sharing and interoperability across the larger community. The BRIDG model is an analysis model for clinical research that covers the entire protocol life cycle from drug development to data analysis. This UML class diagram is a domain friendly conceptual model that also has the technical rigor to be leveraged for building design artifacts like the logical and physical data models, services, data interchange messages, etc. The BRIDG model is being adopted in the industry and academic institutions for developing meta-data repositories & clinical trials databases. It is going through ISO standardization process and has become a de-facto standard for representing the concepts of clinical research. This standard shared understanding of the domain across the various stakeholders is providing the platform to support data sharing and enable meaning-based interoperability.

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