Skip to main content

Ultrasensitive electrochemical detection for matrix metalloproteinase-14 activity using gold nanoparticles amplification

Wednesday, October 10, 2012 — Poster Session II

Noon – 2:00 p.m

Natcher Conference Center, Building 45




  • Z.H. Wang
  • S.H. Chen
  • X.Y. Chen


An ultrasensitive electrochemical sensor for detecting matrixmetalloproteinase-14(MMP14) activity is developed by peptide cleavage with gold nanoparticles as signal amplification. Herein, we prepare peptide-ferrocene (Fc) layer attached to AuNPs film on gold electrodes by lay-by-lay method. Fc is used as an electroactive reporter and peptide as recognition and sensing cleavage site.

back to top