October 9 - 12, 2012
Building 10 & Natcher Conference Center
- General Schedule of Events
- Opening Plenary Session
- Concurrent Symposia Sessions
- National Graduate Student Research Conference
- FARE Award Ceremony
- Poster Sessions
- Special Exhibits on Resources for Intramural Research
- TSA Research Festival Exhibit Show
- Research Festival Committees
- Past Research Festivals
2011 program
Download the 2011 Research Festival Program Book
PDF documents require the free Adobe Reader
Ultrasensitive electrochemical detection for matrix metalloproteinase-14 activity using gold nanoparticles amplification
| Wednesday, October 10, 2012 — Poster Session II | |||
|---|---|---|---|
Noon – 2:00 p.m |
Natcher Conference Center, Building 45 |
NIBIB |
CHEM-16 |
Authors
- Z.H. Wang
- S.H. Chen
- X.Y. Chen
Abstract
An ultrasensitive electrochemical sensor for detecting matrixmetalloproteinase-14(MMP14) activity is developed by peptide cleavage with gold nanoparticles as signal amplification. Herein, we prepare peptide-ferrocene (Fc) layer attached to AuNPs film on gold electrodes by lay-by-lay method. Fc is used as an electroactive reporter and peptide as recognition and sensing cleavage site.
