The Office of Cancer Genomics – Promoting pathways to progress

Wednesday, October 10, 2012 — Poster Session II
Noon – 2:00 p.m	Natcher Conference Center, Building 45	OD	CANCER-3

Authors

• R.S. Broughton
• J.G. Auvil
• S. Behrman
• M. Ferguson
• E.J. Gillespie
• J.C. Zenklusen
• D.S. Gerhard

Abstract

The Office of Cancer Genomics (OCG), within the National Cancer Institute, seeks to advance the understanding of cancer at the molecular level with the ultimate goal of improving clinical outcomes. Through various collaborative and innovative multidisciplinary programs, OCG offers investigators a platform for systematic tumor characterization. The Cancer Genome Anatomy Project (CGAP) is an online resource designed for the research community to access biological tissue characterization data. An outgrowth of CGAP, the Cancer Genome Characterization Initiative (CGCI) utilizes advanced genomic sequencing technologies to provide the scientific community superior genomic data on selected cancer types, including HIV-associated cancers. The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative utilizes state-of the-art genomics tools to identify candidate therapeutic targets in prevalent childhood cancers so that new, more effective treatments can be rapidly developed. Large-scale genomics projects, such as TARGET, generate large volume of data on the molecular changes that underlie the different cancers studied. Finally, the Cancer Target Discovery and Development (CTD2) Network member Centers aim to accelerate the translation of these genomic discoveries into new patient-informed cancer treatments. Data and resources generated by the OCG programs are made publicly available on the OCG website, ocg.cancer.gov.

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