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NIH Research Festival 2006
2006 NIH Research Festival

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October 17 - October 20
General Schedule of Events
Poster Sessions
Plenary Session
Concurrent Symposia
Job Fair for NIH Postdoctoral, Research, and Clinical Fellows
Special Exhibits on Resources for Intramural Research
TSA Research Festival Exhibit Show
Festival Food and Music Fair
Research Festival Committees
Past Research Festivals
Concurrent Symposia
  Wednesday, October 18, 2006
Natcher Auditorium

Predictive Medicine

10:30 am to 12:30 pm

Chaired by Abner Notkins, NIDCR

Main Auditorium, Natcher Conference Center

Medicine is undergoing a paradigm shift from diagnosis and treatment to prediction and prevention.   In the area of prediction several approaches are making it possible not only to predict the likelihood of developing certain diseases, but also the associated complications and response to treatment.  The presentations will describe: (1) how the human genome has opened up a broad spectrum of predictive approaches for both simple and complex genetic diseases by the analysis of individual genes, SNPs and haplotypes;  (2) how protein and RNA microarrays are providing new insight into the nature, course and prognosis of certain ongoing diseases (e.g., cancer); and (3) how autoantibodies which now are know to be present years before the clinical onset of a number of autoimmune diseases (e.g., type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosus) are being used as predictive markers to enter high-risk subjects into therapeutic intervention trials.  The symposium will conclude with a discussion of the cost-effectiveness and ethical pros and cons of predicative medicine.


Genes as Predictors
Francis Collins, NHGRI
RNA as Predictors
Francesco Marincola, CC

Proteins as Predictors
Lance Liotta, NCI         
Autoantibodies as Predictors
Abner Notkins, NIDCR                        
Ethical Issues
Ezekiel Emanuel, CC

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