Co-chaired by Esther Sternberg, NIMH, and Pal Pacher, NIAAA
Joint NIMH Integrative Neural Immune Program/NIAAA Symposium

Conference Room F1/F2, Natcher Conference Center

Neural and neuroendocrine factors play an important role in modulating inflammation and vascular leakiness, and as such play an important role in shock and inflammatory tissue damage.  This symposium will explore several neural and neuroendocrine factors including endocannabinoids, corticotropin releasing hormone (CRH), PACAP, progesterone and the glucocorticoid receptor and other nuclear hormone receptors.  Understanding these interactions will shed light on new treatment strategies for shock and tissue damage. 

Program:

Role of Endocannabinoid System in Hypotensive States
Sandor Batkai, NIAAA

Endocannabinoid System: Emerging Target against Ischemic-reperfusion Injury
Pal Pacher, NIAAA     

Modulatory Role of Bacterial Toxins on Endothelial Barrier Function
Felice D'Agnillo, FDA
 
PACAP and TNF: Multitasking Molecules in Inflammation, Neuroprotection and Neurotransmission
Lee Eiden, NIMH

Effects of Progesterone on Dendritic Cell Maturation and Activation
Cherie Butts, NIMH

Bacterial Toxin Repression of Glucocorticoid and other Nuclear Hormone Receptors: Role in Shock and Inflammation
Alexandra Tait, NIMH, and Esther Sternberg, NIMH