Chaired by:
Eric Green, NHGRI

Balcony A , Natcher Conference Center

The Human Genome Project's recent completion of a high-quality sequence of the human genome represents a landmark scientific accomplishment of historic significance. It also signifies a critical transition for the field of genomics, as the focus shifts from elucidating the human genome sequence to determining its functional code and developing strategies for using the ever-increasing wealth of information to investigate important problems in mammalian biology. This symposium will highlight a few of the most exciting new frontiers in mammalian genomics, in each case involving extensive participation by NIH Intramural scientists. It will include presentations describing: (1) how comparisons of sequences generated from different mammalian species are being used to identify functionally important genomic elements; (2) how sequence-based exploration of the dog genome (in particular) is creating important new opportunities for biomedical research; (3) how the detailed study of variation across the human genome will greatly catalyze future human genetics-based studies, especially those investigating complex genetic diseases; and (4) how computational methods are being developed for comparing genes and genomes and viewing the relationships among them. Together, these presentations should illustrate how the field of genomics continues to mature beyond the human genome sequence.

Program

Decoding the Human Genome by Comparative Sequence Analysis
Elliott Margulies, NHGRI

The Dog Genome: Sequence, Phylogenetics, and Trait Mapping
Elaine Ostrander, NHGRI

The Human HapMap: Construction and Utility
Jim Mullikin, NHGRI

Online Resources for the Comparative Analysis of Genes and Genomes
Greg Schuler, NCBI