A point-of-care multimodal biosensor for screening and monitoring patients with respiratory infectious diseases

Authors

• M Carrasco
• J Zhang
• S Kundu
• E Lee
• M Ferrer

Abstract

The worldwide COVID-19 pandemic has challenged the health care community to develop multimodal biosensors to identify patients with critical signs of a respiratory infection. As a result, we have developed and tested an integrated device consisting of a near-infrared spectroscopy (NIRS) sensor, along with an accelerometer and temperature sensor, capable of monitoring skin temperature, tissue oxygenation and significant respiratory and cardiac parameters. Respiratory and cardiac signals collected from the NIRS device was evaluated using physiological data collected from a commercial system during a pilot study in healthy subjects. During experiment, subjects experienced different breathing exercises including breath holding, paced breathing, and hypercapnia. Preliminary data showed a consistent agreement between measurements from our device with signals measured from the commercial system. In addition, tissue oxygenation measured with our device is better than blood oxygenation measured with a pulsed oximeter in detecting breathing pattern change. In future work, we will use our device to collect data from patients with respiratory infectious diseases and apply a deep learning algorithm to classify signals between healthy volunteers and infected patients using our measured parameters.

Scientific Focus Area: Biomedical Engineering and Biophysics

This page was last updated on Monday, September 25, 2023