NIH Research Festival
We show here that NAPQI, a metabolite of acetaminophen, inhibits the SARS-CoV-2 papain-like protease (PL-Pro). Previous reports show that PL-Pro inhibitors prevent viral spread in model organisms. We hypothesize that OTC medications containing acetaminophen taken early in infection may prevent viral spread. Further study may be warranted.
Scientific Focus Area: Virology
This page was last updated on Monday, September 25, 2023